Mesalamine Its Use In Ulcerative Colitis And Treatment With Ayurveda
Abstract
Ulcerative colitis is an inflammation of the colon. Bacterias such as E.Coli, Campylobacter, Shigella, Yersinia, and salmonella affect the innermost layer of the colon. Anti-inflammatory drugs are the first line of drugs for the treatment of ulcerative colitis. Due to various side effects associated with the drugs Ayurveda plays a vital role in managing and preventing ulcerative colitis without any side effects. Let’s have a look!!!
Introduction
Ulcerative colitis (UC) is an inflammatory bowel disease that causes inflammation and ulcers in your digestive tract. UC affects the innermost lining of the large intestine, also called the colon and rectum. Bacteria that cause colitis include E. Coli, Salmonella, Campylobacter, Yersinia, and Shigella. Other body organs may be impacted by the toxins that the bacteria can create or by the illness itself. Our digestive system, often known as “Agni,” performs a number of tasks including digestion, nutritional absorption, and assimilation of food particles. When this Agni isn’t functioning properly, food particles are improperly or insufficiently digested, which frequently results in an accumulation of AMA (toxins), which the body absorbs and stores. The release of different digestive juices is impacted by the accumulated AMA, which results in a compromised digestive metabolism. It mainly targets people in the 15-30 age group and then again at 50-70. It can be detected by medical tests which include blood tests, stool tests, and endoscopy of the large intestine.
There are four types of ulcerative colitis i.e.
- Ulcerative Proctitis
- Proctosigmoiditis
- Left-sided Colitis
- Pan-ulcerative colitis
Symptoms of ulcerative colitis
- Abdominal pain and cramping
- Blood and pus in stools
- Loss of appetite
- Diarrhea
- Tenesmus
- Anaemia
The first-line treatment for ulcerative colitis is anti-inflammatory drugs. Mesacol/ Mesalamine belongs to the class of aminosalicylate and is used to treat ulcerative colitis. The other treatment options for UC are immunosuppressants, biologics, surgery, and others (Anti-diarrheal, pain relievers, antispasmodics, and iron supplements). Mesacol functions by reducing the generation of chemical messengers (prostaglandins) that lead to intestinal inflammation and edema. It reduces stomach pain, bleeding, and ulcers. It is used for mildly to moderately severe diseases. It is taken by mouth and rectally. It comes in a delayed-release and extended-release dosage forms.
Salt composition and synonyms of mescal: Mesalazine and mesalamine
Use of mescal: Ulcerative colitis, Crohn’s disease
Side effects of mescal: Diarrhea, headache, itching, nausea, flatulence, dizziness, muscle pain, vomiting, joint pain
Marketed formulations (Brand names):
- Tablet- 5A, Asacol, Mesacol, Pentasa-500, Tidocol, Walasa
- Suppository- MesacolSuppos
- Enema- Mesacol Enema
Storage: Store in a cool and dry place away from sunlight
But according to Ayurvedic philosophy, an unbalanced dosha can cause the interruption of the life energy (prana), which can cause digestive issues and build-up waste. Pitta pradhan Vata doshas, an imbalance between pitta and vata in which vata is heightened by pungent and bitter flavors, are regarded to be the disease-causing factor in ulcerative colitis.
According to Ayurveda, this digestive problem is primarily brought on by a regular intake of imprudent food (spicy, oily, frozen food), an unsupportable lifestyle (lack of exercise, sleep, etc.), Roga (infections), and Vyadhikshamatva (low immunity). These factors together weaken the Pachak Pitta (digestive fire), which in turn leads to this problem.
Factors that cause ulcerative colitis include
- Excessive sun exposure or heat
- Alcohol intake and excessive smoking
- Stress
- Eating infected, stale, and rancid food
- Improper eating habits
Agni Deepana (improving appetite), Ama Pachana (measure to digest the Ama), and strengthening graham (gastrointestinal system) are the basic treatment lines followed by Ayurveda.
Herbs and foods that manage ulcerative colitis disorder
- Green grass also known as Durva grass stops bleeding and helps in healing ulcers.
- Vegetables such as gourds, long gourds, round gourds, bitter gourds, and pumpkins are good for managing colitis disorders.
- Coconut water and marigold flower petals are also good for ulcerative colitis.
Home remedies for ulcerative colitis
- Specific Asanas, Meditation, Pranayama, and deep relaxation of the body
- Change in lifestyle may help to treat ulcerative colitis
- Turmeric, cumin, coriander, and celery in a diet plan can help in preventing ulcerative colitis as they are rich in antioxidants and vitamins.
Herbal remedies for ulcerative colitis by Planet Ayurveda
Planet Ayurveda is a GMP-certified company that manufactures numerous products for various diseases. All the products are prepared by following ancient Ayurveda principles under the guidance of MD Ayurveda experts. For UC, Planet AYurveda has a UC care pack along with numerous other formulations. Let’s have a look!
Product List
1. Arjuna Capsules
2. Vatsakadi Churna
3. Pitta Balance
4. Kutajghan Vati
Product Description
1. Arjuna Capsules
Arjuna capsules are prepared using a standardized extract of Arjuna (Terminalia Arjuna) and to have wound healing properties, it targets the inner lining of the intestine. It helps to stop bleeding, and ulcers, controls diarrhea, and prevents inflammation. It also improves the hemoglobin level and strength of the person.
Dosage: 2 capsules twice daily with plain water after a meal.
2. Vatsakadi Churna
Vatsakadi churna- It is a mixture of Kutaz (Holarrhena antidysenterica), Saunf (Foeniculum vulgare), and Bilva (Aegle marmelos) and helps to heal the ulcers and get rid of the disease. It is also very good for mucus control and restricting diarrhea.
Dosage: 1 teaspoon twice daily with plain water after a meal.
3. Pitta Balance
Pitta balance is a combination of various calcium compounds which helps to control the bleeding and has a cooling effect on the body.
Dosage: 1 capsule twice daily with plain water after a meal.
4. Kutajghan Vati
Kutajghan vati- It is prepared using Kutaj also called antidysenterica and it is nature’s wonder which has the power to stop all sorts of diarrhea. It helps to burn “ama or endotoxins”, stops inflammation, stops fermentation going on inside the intestines, and heals ulcers.
Dosage: 2 tablets twice daily with plain water after a meal.
Prevention for ulcerative colitis
- Water intake should be high
- Include fibrous food and fiber supplements in your diet
- Avoid carbonated drinks and have smaller meals in a day
CONTACT PLANET AYURVEDA TO PROVIDE YOU WITH THE COSTING / ORDERING AND DELIVERY INFORMATION AT – COSTING.PLANETAYURVEDA@GMAIL.COM OR CALL AT +91-172-5214040
Conclusion
In the end, it is concluded that Ayurveda plays a vital role in treating disorders without any side effects. There are various Ayurvedic medicines that are available in the market and can treat ulcerative colitis without any side effects, some of which are discussed in the above article. In case of any query, kindly visit www.PlanetAyurveda.com. A complete product description is available on-site.
