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Severe Combined Immunodeficiency (SCID) Treatment in Ayurveda

Severe combined immunodeficiency

Abstract

Severe combined immunodeficiency is a rare genetic disorder due to disturbed functional development of B cells and T cells caused by genetic mutations that leads to alteration in clinical presentation. It is also known as bubble boy disease or bubble baby disease and swiss-type agammaglobulinemia. Severe combined immunodeficiency is a fatal condition without gene therapy or transplant of stem cells. There are approximately 13 kinds of genetic defects that may lead to SCID. These defects further cause extreme prone to serious infections. Infants with 80% SCID have no family-related history of this disease. So, today we will read about severe combined immunodeficiency in brief in this article.

Severe Combined Immunodeficiency (SCID)

Introduction

It is a rare condition caused by genetic mutations that leads to alteration in function and development of immune cells. Newborns with severe combined immunodeficiency look healthy at the time of birth but are extremely susceptible to serious infections. This is a fatal condition until or unless newborns receive treatment for immune restoration like gene therapy, enzyme therapy, or hematopoietic stem cells.

Cause

Severe combined immunodeficiency caused by

  • Genetic mutations
  • Adenosine deaminase deficiency
  • Purine nucleoside phosphorylase deficiency
  • Reticular dysgenesis
  • Omenn syndrome
  • Bare lymphocyte syndrome
  • CD3 chains deficiency
  • Janus Kinase 3 deficiency

Symptoms

  • Recurrent infections
  • Weakness
  • Rashes
  • Delayed growth
  • Difficulty in weight gain
  • Diarrhea
  • Pneumonia
  • Respiratory infections
  • Failure to thrive
  • Oral thrush
  • Sinus infections
  • Ear infections

Diagnosis

  • A full blood lymphocyte count
  • DNA test for genetic mutation
  • Newborn screening test

Treatment

  • Bone marrow transplant
  • Chemotherapy
  • Gene therapy

Prevention

You can decrease the risk of infection to your baby by

  • Avoiding public places
  • Prevent baby from infection or cold
  • Limiting visitors
  • Wash the hands properly before touching the infant.

Ayurvedic overview

In Ayurveda, we can correlate this disease with anuvanshik vyadhi (inherited disease) and other is oja kshaya (immune deficiency). Anuvanshik vyadhi is developed in a person by birth due to deformity in beej dosha (sperm and ovum deformity). Oja means resistance to diseases or immunity against diseases is of two kinds: one which attenuates the manifested disease and other variety prevents the manifestation of diseases. Factors which contributes for oja (immunity) are normal doshas (vata, pitta and kapha), equilibrium state of dhatu, normal agni, patency of srotas etc are the factors which supports the equilibrium state of all physiological parameters. Ojas is the essence of rasadhi dhatus and it is also called bala (strength).

Ojas Kshaya Etiological Factors

According to S.Su 15/23 sholaka

Ojas undergoes decrease due to injury, Tissue depletion, anger, grief, worry, exertion, hunger etc are resulting into the flowing out from the dhatus and getting associated with tejas and instigated by vata, which gives various discomfort to the body.

Clinical Features of Oja Kshaya

मूर्छा मांस क्षयो मोह: प्रलापो मरण मिति च क्षये। (S. Su 15/24)

According to the above mentioned shloka

  • Fainting
  • Wasting of muscles
  • Unconsciousness
  • Delirium
  • Death

Oja kshaya and anuvanshik vyadhi is an incurable entity because it produces due to improper understanding. We can only give supportive treatment of herbal medicines to inhibit the progression of the disease.

Herbal remedies for SCID by planet ayurveda

Planet Ayurveda is a manufacturing unit of different kinds of ayurvedic medicines for various kinds of diseases which shows effective results in the human body. They strictly follow all the principles of ayurveda which are described in ancient textbooks of ayurveda. All these herbal medicines are GMP certified and pure vegetarian. These are safe to use for the human body. There are no additives, preservatives, chemicals, yeast etc.

In this disease, no specific treatment is available till now. Only supportive treatment will be given which can delay the progression of the disease and provide some immunity to fight against other infections. The planet ayurveda provides herbal remedies for severe combined immunodeficiency which are following

Product List

  1. Telomere Boostup
  2. Immune Booster
  3. Amalaki Rasayan
  4. Ashwagandha Capsules
  5. Shilajit Capsules
  6. Gandhak Rasayan

Severe Combined Immunodeficiency (SCID)Buy Now: Herbal Remedies for SCID

Product Description

1. Telomere Boostup

It is a polyherbal capsule containing grape seed (vitis vinifera), amalaki (Emblica officinalis), ashwagandha (withania somnifera), etc. It is sweet, astringent, and bitter in taste. It is light, dry and hot in effect. It contains alkaloids, glycosides, flavonoids, amarin, gernanin, etc. It has a tonic effect on the brain and the nervous system. It acts as an anti-inflammatory, analgesic, aphrodisiac, diuretic and mildly sedative. It is an immune-modulator, antioxidant and hormone precursor which tends to regulate important physiological functions. It improves general alertness, prevents all types of weakness and increases strength and stamina. It also allays the stubborn and recurring infections of the urinary tract. It keeps the heart healthy and prevents free radical damage. It induces sound sleep and reduces inflammation.

DOSE:- 1 Capsule twice daily with plain water, after meals

2. Immune Booster

It is a polyherbal capsule containing grape seed (vitis vinifera), bhumi amla (Phyllanthus niruri), amalaki (Emblica officinalis), etc. It is sweet, astringent, bitter and pungent. It is light, dry and cold in effect. It contains alkaloids, glycosides, flavonoids, etc. It raises immunity and helps in fight day to day wear and tear of the body. It is used in fever, anemia, and disease of the urinary and genital tract. It also acts as a booster for all physiological systems of the body. It acts as hepato-protective and helps to manage liver diseases. It contains antioxidants which clear all the channels of the body and expel the toxins from the body and prevent ulcer by decreasing the amount of gastric acid. It is indicated in various diseases like cough, sore throat, indigestion, vomiting, hyperacidity, peptic ulcer, anemia, etc. it also allays the stubborn and recurring infections of the urinary tract. It keeps the heart healthy and prevents free radical damage.

DOSE:- 2 Capsules twice daily with plain water, after meals

3. Amalaki Rasayan

It is a single herbal capsule made from amalaki (emblica officinalis). It is at the same time sweet, astringent, bitter and pungent. It is dry, light and cold in effect. It is rich in protein, minerals, carbohydrates and fibre. The mineral and vitamin contents include calcium, phosphorus, iron, carotene and also vitamin b complex. It acts as an antipyretic, antioxidant, astringent, laxative, diuretic, aphrodisiac, antacid, and haemostatic. It is indicated in epistaxis, dysfunctional uterine bleeding, leucorrhoea, menopausal syndrome, general emaciation, hair and eye problems, jaundice, edema, cough and asthma. It also helps in healing the ulcers. It acts as a good antioxidant and also an adjunct in many chronic and wasting diseases.

DOSE:- 1 Capsule twice daily with plain water, after meals

4. Ashwagandha Capsules

It is a single herbal capsule made from ashwagandha (withania somnifera). It is sweet, bitter and astringent in taste and unctuous, light and hot in effect. It is tonic, rejuvenating and potent spermatogenic. It has a tonic effect on the brain and the nervous system. It acts as an anti-stress and adaptogenic medicine. It has anti inflammatory, analgesic, aphrodisiac, diuretic, and mildly sedative properties. It is also an immune-modulator, antioxidant and hormone precursor which tends to regulate important physiological functions. It is indicated in nervous and psychiatric disorders, arthritis, low backache, emaciation, impotency, hypertension and insomnia. It improves general alertness, prevents all types of weakness and increases body strength.

DOSE:- 2 Capsules twice daily with plain water, after meals

5. Shilajit Capsules

It is a single herbal capsule made from shilajit (asphaltum). It consists of rock humus, organic substances and rock minerals and components are resins, fatty acids, sterols, coumarins, gums, latex, albumins, triterpenes, phenolic lipids, aromatic carboxylic acids and amino acids. It has an anti inflammatory, anti tumor activity, antioxidant, anti-alzheimer, anti-asthmatic properties. It improves digestion related problems and enhances memory power. It controls the blood sugar in the body. It is beneficial in kidney, heart and liver diseases. It increases the hemoglobin in the body.

DOSE:- 1 Capsule twice daily with plain water or milk after meals

6. Gandhak Rasayan

It is a herbal tablet made from shuddha gandhak (purified sulfur). It is an antimicrobial, antibacterial, antipyretic, anti-allergic, anti-inflammatory antiviral and a broad spectrum antibiotic. It kills intestinal worms and is a good blood purifier. It contains various antioxidants. It is an immunity booster and indicated in infertility, debility, indigestion, breathlessness, abdominal pain. It detoxifies the blood, impurities, clears dirt and prevents secondary infection. It is very useful in urinary tract infection along with expelling the harmful pathogen from the body system.

DOSE:- 2 Tablets twice daily with lukewarm water

Contact Planet Ayurveda Support Team to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or Call at 0172-521-4030 (India), +91-172-521-4030 (Outside India) or Whatsapp at (+91) 9915-593-604

Conclusion

Severe combined immunodeficiency is the rare genetic condition in which genetic mutations occur which leads to alteration in function and development of immune cells. In ayurveda, we can correlate this disease with anuvanshik vyadhi (inherited disease) and other is oja kshaya (immune deficiency). There is no specific treatment for this disease but we can give supportive treatment to delay the progression of disease. We can use various kinds of herbs like shuddh gandhak, ashwagandha, amalaki, shilajit, bhumi amla, grape seed, etc which are very effective in this disease and provide immunity to the body. Herbal medicines like gandhak rasayan, telomere boostup, amalaki rasayan, ashwagandha capsules, etc.

Physical Activity Level (PAL) Test and Ayurveda for Crab Allergies

Physical Activity Level (PAL) Test

Introduction to the Pal Test

The PAL test is also known as the Physical Activity Level test. This is a measure of individual physical activity level; testing. The test is performed on the person to evaluate his total energy expenditure daily. The daily energy expenditure can also be defined as the amount of energy that the body needs for daily functions.

Physical Activity Level (PAL) Test

The PAL test is typically done to evaluate the daily energy of the person (that includes- diet and weight management. The calculation involves dividing the basal metabolic rate by the total energy expenditure of the particular person, (that is BMR/energy expenditure per day is equal to the PAL score). Talking about the value or levels of PAL scores can vary from

  • Less than one for people who follow a sedentary lifestyle.
  • PAL score of two for people performing high energy-consuming daily activities.
  • PAL score above two

The above two is found rarely but is an alarming condition that indicates the usage of excess energy by the person daily that can be harmful if the person is not taking adequate amounts of calories, minerals, and other essential nutrients to match the levels of high energy expenditure. We will be discussing its alarming results further in this article. Thus, a proper evaluation can be done and estimated to maintain adequate energy and maintain the proper general health of the particular person.

Significance of the PAL test

The PAL test provides essential information regarding the daily energy expenditure of the person to meet the daily energy requirement by him. The detailed significance of the PAL test provides information regarding various health-related purposes such as

Appropriate Dietary Plans

Knowing the person’s PAL score, assure their professionals about the requirement of diet and dietary contents that can help in planning the exact dietary content addition and avoidance to meet the recommended needs for that particular person.

Achieving Fitness

The physical activity and exercise hours can be managed through PAL score evaluation. The person can be suggested or recommended to do certain necessary physical activities to burn excess calories to achieve fitness goals.

Managing Weight

The PAL score can help you to estimate the factors and needs for weight management. According to the score, the professional can suggest adding calories to gain weight or avoid certain food items that have excess calories, that are putting weight on.

Prevention and Management of Diseases and Disorders

Evaluating and understanding the PAL score of a patient suffering from disorders such as obesity, heart disease, diabetes, and other disorders can help the health professional to manage the adverse symptoms by managing energy requirements and expenditure daily.

Thus the PAL score can be used to help with appropriate diet plans, managing weight, achieving fitness planning, and prevention of diseases and disorders.

The High Levels of PAL Test Are Alarming

The high levels of PAL score refer to a score of two and most probably above two. These High levels of the PAL test as explained earlier could be alarming and can show negative results.

These high levels (of the PAL test) show that the person is engaged in high physical activities throughout the day, which can show outcomes of high energy expenditure, and if this high energy expenditure (through physical activities) is not accompanied by appropriate and adequate calories, essential nutrients, and minerals intake, it could show alarming results such as energy imbalance in the body and disturbed weigh management. These alarming signs can prove to be fatal in managing many disorders and achieving fitness.

Also, daily excessive physical activity can cause injury in the body areas along with muscular problems. Plus, a certain amount of nutrients are required to perform daily physical activities, which must be taken every day. Lacking in intake of the required calories and diet could lead to many malnutritional disorders.

But, we must also know that a high PAL score not only indicates high energy expenditure in each individual but can also occur as a result of certain medical conditions such as- hyperthyroidism (a common abnormality of the thyroid gland that can show a high PAL score, lead to nutrients deficiency, weight loss, increased metabolism).

Thus, high levels of PAL tests can be alarming due to various reasons mentioned above and should be carefully evaluated to correct the exact cause of the high score.

What Ayurveda Can Offer

Crab Care Pack by Planet Ayurveda

Planet Ayurveda is a leading Ayurvedic medicine manufacturing company that offers a wide range of natural medicine worldwide. The health supplements are herbal and used efficiently for managing various disorders. The Crab Care Pack is one of their patent products that are potent to manage conditions and disorders related to high PAL score.

The Crab Care Pack contains the following Ayurvedic herbal supplements

Product List

  1. Aller-G Care Capsules
  2. Curcumin Capsules
  3. Praanrakshak Churna
  4. Tulsi Capsules

Crab Care PackBuy Now: Crab Care Pack

Product Description

1. Aller-G Care Capsules

These classical polyherbal capsules of Planet Ayurveda contain a blend of natural herbs, including Haridra (Turmeric), Ashwagandha (Withania somnifera), Neem (Azadirachta indica), and Shirish (Albizia lebbeck). This combination of herbs helps to support the immune system and reduce inflammation, which can help to alleviate the symptoms of crab allergies.

Dosage- Take 1 capsule twice daily.

2. Curcumin Capsules

Curcumin capsules of Planet Ayurveda are pure Ayurvedic capsules. These capsules contain a standardized extract of Curcumin, which helps to reduce inflammation and relieve allergic symptoms due to its anti-inflammatory and antioxidant properties.

Dosage- Take 1 capsule twice daily.

3. Praanrakshak Churna

This potent ayurvedic herbal powder contains a blend of natural herbs, including Vasa (Adhatoda vasica), Shirish (Albizia lebbeck), Anantmool (Hemidesmus indicus), and Dalchini (Cinnamomum zeylanicum). These herbs help to support respiratory health and relieve respiratory allergies.

Dosage- Take 1 teaspoon twice daily.

4. Tulsi Capsules

Tulsi (Holy Basil) is a natural herb that is well known for its immune-supporting properties. These capsules contain a standardized extract of Tulsi, which helps to support the immune system and relieve allergic symptoms.

Dosage- Take 1 capsule twice daily.

Contact Planet Ayurveda Support Team to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or Call at 0172-521-4030 (India), +91-172-521-4030 (Outside India) or Whatsapp at (+91) 9915-593-604

All these above-mentioned Ayurvedic medicines are formulated using organic herbal ingredients that are free from harmful chemicals. Thus are safe and effective for long-term usage in many disorders (associated with PAL score) and can be taken by people of all ages under the guidance of a professional Ayurvedic doctor. For more queries please visit us at www.planetayurveda.com