Category: Herbal Remedies

Efficacy Of Dostarlimab In Treating Cancer And Its Effects And How Ayurveda Helps In It?

Abstract

Normally in our body cells grow and divide and later on die and get replaced but in cancer these cells grow abnormally and spread to whole tissues of the cell wall and grow as a tumor (a growth or lump). Tumors can be benign or malignant. Benign tumors are not cancerous but malignant growth are cancerous. They can be solid tumors or the cancer of the blood called leukemias. Benign tumors do not spread to other parts and remain localized to one part of the organ and after removal it doesn’t grow back. But sometimes benign tumors are dangerous as in the brain. So in this article, we are going to discuss an anticancer drug named Dostarlimab and see what are the alternatives of Dostarlimab in ayurveda!

Dostarlimab

Introduction

Dostarlimab is a drug which is used to treat cancer, is a IgG4 monoclonal antibody which is targeted against Pd-1. The cancer which is invaded into the tissues grows uncontrollably and spreads to the whole parts of the body. In normal body structure the cells grow only when they receive the signal. Cancer is a genetic disease, and is inherited from the parents and many other environmental factors affect the growth of cells. The genetic changes which are affecting are: proto – oncogenes (they are involving normal cell growth and that cells start working more actively and causes cancer causing genes in the body), tumor suppressor genes (they are controlling the normal growth) Dna repair genes (they are helping in fixing the damaged Dna where they causes mutations and this mutation leads to duplication and at end lead to cancer growth).

Spread Of Cancer

Cancer spread from site of origin to another place is called metastatic cancer, and this process is called metastasis. We can examine this metastatic cancer under a microscope which appears the same as the original cancer.

Types Of Cancer

There are many types of cancer which start from the name of the organ such as lung cancer starts from lung, brain cancer starts from brain, and many cancers formed from cells that are epithelial cells, squamous cells.

  1. CARCINOMA – Formed by epithelial cells and the most common type of cancer. Are present in different cells – such as adenocarcinomas that produce fluids called glandular tissues.
  2. SARCOMA – Forms in the bone (osteosarcoma), in the lymph vessels, and in the fibrous tissues (tendons and ligaments).
  3. LEUKEMIA – Cancer which begins in the blood and causes leukemia. Forms large numbers of white blood cells are built in the bone marrow.
  4. MELANOMA – It is the cancer of the pigment known as melanin. Can also be seen in the eyes.
  5. TUMORS –
    1. Germ cell tumor can be found at any part of the body but generally arises from the cells giving rise to sperms and eggs.
    2. Carcinoid tumors are a type of neuroendocrine tumor. Are mostly found in the gastrointestinal system and spread to the liver and many other parts of the body.

Causes Of Cancer

  • Family History – Can be due to some genetic mutations, or can be exposure to certain medicines.
  • Lifestyle Changes – Main factor that causes cancer is sedentary lifestyle and high fat diet, smoking.
  • High Dosage Of Chemicals – Infants are more prone to cancer due to exposure to insecticides, fertilizers, and pesticides.

Efficacy Of Dostarlimab In Treating Cancer

Dostarlimab is used in patients who are suffering from recurrent endometrial cancer. It is a monoclonal antibody which binds to the Pd-1 receptor and it blocks the action of proteins in cancer cells. Pd -1 is a bound to protein Pd-L1 which kills the cells, and Pd-1 manages the immune system of the body. When Pd-1 acts it facilitates the antitumor activity and treats many cancers. Dostarlimab is given for 30 minutes via iv infusion every 3-6 weeks. Dostarlimab is a life threatening medication which can cause many symptoms in patients so it should be given strict guidance of nurses and doctors.

Indications

Given in patients who are not treated with chemotherapy, endocrinopathies, hepatitis with tumor involvement of the liver. And with patients who have been treated but there is recurrence of cancer causing cells. This drug slows down the growth of tumors or slows down its speed. Dostarlimab is blocking certain channels of the protein pathway.

Special Precaution Before Taking Dostarlimab

  • Patient must inform the doctor about his / her allergies.
  • Patient must tell him about his medicines he / she is taking such as – multivitamins, nutritional supplements, so that the doctor may take more care of the patients.
  • If patient is suffering from any disease such as ulcerative colitis – which causes sores in the lining of the colon), Guillain barre syndrome (which is caused due to nerve damage), any liver disease, thyroid disease hypothyroidism, hyperthyroidism, myasthenia gravis (rapid weakness of the muscles).
  • If a patient is breastfeeding then this drug is not advised.

Side Effects Of Dostarlimab

  • He / She may feel weakness in joints
  • Increased sweating
  • Increase in appetite
  • He / She may listen to voices that don’t exist.
  • He / She may feel fever, nausea, vomitings, sometimes this medication causes seizures, eye pain, stomach pain.

Ayurveda Aspect on Dostarlimab

Cancer is a disease which is common in many countries worldwide , and the main cause of it is an imbalanced diet or more use of dirturbed food habits of every person. According to acharya, sushrut (father of surgery) said that cancer is caused due to accumulation of aggravated doshas in any part of the body – as in excess growth which is caused in mammals called mamsa arbuda. According to doshas there are many types of cancer –

  1. Vataj arbuda
  2. Pittaja arbuda
  3. Kaphaja arbuda
  4. Rakta arbuda – This condition gives rise to anemia because these doshas take their place in vessels (sira).
  5. Medo arbud – This is the metastatic growth.

Drugs used in Treatment of Cancer

  1. Devadaru (Cedrus deodara): It is known as himalayan cedar which is very useful in neurological disorders. There are two varieties of devadaru – devadaru (cedrus deodara) and sarala devadaru( pinus longifolia). Devadaru is tikta (bitter) katu (pungent) kashaya (astringent) in taste. It has rookshan (dry) guna. Its vipaka is katu and has ushana veerya. It balances kapha and vata dosha. The parts used are bark, leaves, resins. It is very useful in indigestion and altered metabolism. Treated in obesity.
  2. Aragwadha (Cassia fistula): It is mainly used in constipation and in many skin diseases. It has mrudu (soft), guru (heavy), and snigdha (oily) gunas. Its vipaka is converted after digestion. It has sheeta veerya. Balances kapha and pitta dosha. It has cardioprotective properties and blood purifiers too.
  3. Langali (Gloriosa superba): Used in treatment of wound healing, during labor if one feels difficulty, or worm infestation. Langali has katu (pungent) tikta (bitter) rasa. Has ushana veerya, its main action is to abortifacient, and is kapha and vata shamaka.
  4. Kshara – It has alkali property and is used to relieve the tridosha. Kshara is pungent and has ushna veerya , it heals the wound and has stambana property.

Crab Care Pack By Planet Ayurveda

Crab Care Pack is manufactured by planet Ayurveda under all the ayurveda guidelines. Planet Ayurveda prepares all formulations which are made of natural herbs which are beneficial for our health. Planet Ayurveda is providing various preparations such as ashwagandha capsules, curcumin capsules, tulsi capsules, chandraprabha vati, guggul capsules. All these products made are natural herbal preparation without any animal extract and are free from any preservatives. These products are hundred percent natural under guidance of MD doctors. These formulations are prepared according to procedure described in the samhitas, therefore are much effective in promoting health of the patient.

This pack consists of herbal medications such as

  1. Ashwagandha Capsules
  2. Curcumin Capsules
  3. Kanchnaar Guggul
  4. Tulsi Capsules
  5. Guggul Capsules
  6. Chandraprabha Vati

Herbal Remedies

Products Description

1. Ashwagandha Capsules

Ashwagandha capsule is one of the herbal formulations of planet ayurveda which contains ashwagandha (Withania somnifera)- used in treatment of depression, antioxidants, and leucoderma. This drug is a stress reliever drug and it improves the quality of sleep. It works as a rasyan and has rejuvenate properties. Helpful in reproductive organs and give more support to joints and give healthy muscle. Ashwangandha balances vata and kapha.

Dosage: 1-2 capsules twice daily with plain water after meals.

2. Curcumin Capsules

Curcumin capsule is herbal formulation of planet ayurveda which contains curcumin (Curcuma longa) Turmeric powder when mixed with ark and made a paste can be easily applied on pile mass. It has antioxidant properties as it has ushna veerya and has katu tikta rasa, haridra cleanses the rasa and it is helpful in removing the blocked channels which are contaminated by doshas. It has immune modulation action as it regains strength and brings immunity. Haridra is helpful in diabetes patients.

Dosage: 1-2 capsules twice daily with plain water.

3. Kanchnaar Guggul

Kanchnaar guggul is herbal formulation of planet ayurveda which consists of kachnar bark, amalaki, haritaki, bibhitaki, trikatu (ginger, black pepper, pippali) varuna bark, cardamom, cinnamon, tejapatra, guggul. It is very useful in treatment of goiter and in many wound healing sinuses. It is helpful in the treatment of obesity as it contains triphala and trikatu. It is useful in PCOD, polyps, and lipoma.

Dosage: 1-2 tablets twice daily with plain water after meals.

4. Tulsi Capsules

Tulsi capsule is herbal formulation of planet ayurveda which contains tulsi (Ocimum sanctum)- is holy basil. Used in reducing the ill effect of radiotherapy. It has good taste and is mainly used in all households, has a good scent and is a beautiful inflorescence. It has katu and tikta rasa, laghu and rooksha teekshna guna. Has ushna potency. It balances vata and kapha dosha (as it decreases excessive sputum) but increases pitta dosha. The parts used are leaf root and seed. Useful in skin disease and relieve difficulty in urination.

Dosage: 1-2 capsules twice daily with plain water after meals.

5. Guggul Capsules

Guggul capsule is herbal formulation of planet ayurveda which contains guggul. It has binding properties, helpful in decreasing the level of cholesterol and useful in joint problems. Guggul has many effects on musculoskeletal parts as it provides strength to ligaments, bones, muscles. So lakshadi guggul is mainly used in dislocations. Main property of guggul is to rejuvenate and provide strength and is a good anti-inflammatory drug. Has tikta and katu rasa, ushana veerya , it brings clarity and clears the channels.

Dosage: 1-2 capsules twice daily with plain water after meals.

6. Chandrprabha Vati

Chandraprabha vati is one of herbal formulation of planet ayurveda which consists of asphaltum (shilajit), commiphora mukul (guggul), sugar, cinnamomum camphora (karpoor), acorus calamus (vacha), cyperus rotundus (mustak), piper chaba (chavya), embelia ribes (vidanga), tinospora cordifolia (guduchi), piper longum (pippali). This formulation is Used in thyroid disease, kidney pancreas and it brings glow to face and body and it provides strength and increases immunity. It is Very useful in ashmari, vibandha (constipation), mutraghata (urinary obstruction) pandu (anemia). Chandraprabha vati is very useful in reducing the sugar content in urine, and it decreases pain and cramps and plays an important role in menstruation and provides strength to muscles of the uterus.

Dosage: 1-2 tablets twice or thrice daily with lukewarm water.

Conclusion

Dostarlimab is a drug used for treating endometrial cancer. This drug is a monoclonal antibody. Cancer is a disease where the cells of the body grow uncontrollably and later spread to the whole part of the body. Normal cells grow, break and die but in cancer they form a tumor, tumor can be benign or malignant. Dostarlimab is a medicine used in treatment of endometrial cancer or where cancer is grown back .We came to know about the spread of cancer, dostarlimab efficacy, and we came to know about the types of cancer which can cause harmful effects on the body. And then read about the ayurvedic aspect of how doshas and many other agents grow cancer, and herbal medications are discussed

Herbal Supplements Available to Fulfil the need of Multivitamins to our Body

ABSTRACT

Multivitamins are key ingredients that are essential for maintaining our health. And functioning of our bodily activities and mental stability as well. At present, Food is contaminated with chemicals and adulterated and devoid of essential vitamins that leads to nutrient deficiency disorders. In order to get proper nutrition, health supplements that contain multivitamins become important. Let’s discuss it in detail!

Multivitamins

INTRODUCTION

In India and all around the globe, people have shifted from their traditional diet to junk food and other preservatives containing edibles. This has added to many deficiency disorders and further obesity. Junk foods do not provide any benefit but diseases. These foods don’t provide what our body needs to accomplish its functions. Thus it directly links to nutritional deficiency disorders. In order to overcome this, we need to get our diet in order or there is another way with multivitamin supplements.

NEED OF MULTIVITAMINS TO OUR BODY

Multivitamins come with essential nutrients that our body needs in order to function properly and remain disease free. So it becomes mandatory to follow a diet that is enriched in multivitamins and other minerals. In case if a person is not getting proper nutrition, he becomes prone to certain nutritional deficiency disorders and general weakness becomes a primary symptom.

What Ayurveda has to serve

According to ayurveda, immunity which is correlated to oja, is essential to fight various diseases. Oja is the most purified form that is formed after the assimilation of food through various dhatu poshan krama. So Oja is an abstract of food that a person consumes. Considering this fact it is really important if a person is taking nutritious food in order to achieve this abstract that helps in keeping body disease free. So it is essential to eat nutritious food to promote well being. In ayurveda, where herbs provide basic nutrition, side by side it is also helpful in various diseased conditions.

Following are some vitamins with their function and what their deficiency can cause.

1. Vitamin A

  • Function : Involved in  cell communication, vision, cell growth and immune function.
  • Deficiency causes : Night blindness and xerophthalmia.

2. Vitamin B1

  • Function : Helps in changing carbohydrates into energy.
  • Deficiency causes : Beriberi

3. Vitamin B2

  • Function : Produces energy by converting carbohydrates into glucose.
  • Deficiency causes : Glossitis.

4. Vitamin B6

  • Function : Involved in more than 100 enzyme reactions in the body and involved in protein metabolism.
  • Deficiency causes : Microcytic anaemia, swollen tongue, scaling of the lips and cracks in the corners of the mouth, confusion and depression.

5. Vitamin B12

  • Functions : Involved in red blood cell formation, neurological function, and DNA synthesis.
  • Deficiency causes : Megaloblastic anaemia, weakness,fatigue, loss of appetite, constipation and weight loss.

6. Vitamin C

  • Functions :  Involvement in the formation of certain neurotransmitters, protein synthesis and collagen.
  • Deficiency causes :  Scurvy, fatigue, inflammation of the gums and connective tissue weakness.

7. Vitamin D

  • Functions : Enhances calcium absorption, bone formation and is involved in  immune function, cell growth,, and reduces inflammation.
  • Deficiency causes : Rickets in children or osteomalacia in adults, fatigue.

8. Vitamin E

  • Functions : Maintains sexual health.
  • Deficiency causes : sterility in males and abortions in females.

9. Vitamin K

  • Functions : Helps in blood clotting, bone health.
  • Deficiency causes : Excessive bleeding.

Conditions when Nutrition is needed in Abundance

  • In pregnancy, a woman needs as much nutrition as her body demands. Thus health supplements become important.
  • In toddlers, as the body grows, nutrition is required for growth and immunity build up.
  • In elderly, calcium and vit d is required to combat deficiency and wear off  calcium.
  • In general, nutrition is required to do daily activities.

Home Remedies to Help with Multivitamin Deficiency

  • Nuts  (Almonds and walnuts) are rich in VitB1,B2,B6, Vit E, calcium, iron, copper,  selenium and other minerals. Thus 5-10 nuts can be taken in the morning after soaking overnight.
  • Mushrooms can be taken after properly cooking it in soups, sandwiches etc. Mushrooms are rich in Vit B2,B3,B5 Vit D thus overcomes nutritional deficiencies.
  • Green peas can be consumed after cooking. It contains Vit A, B1, E, Beta carotene, zinc. It boosts immunity. And also helps in various disorders.
  • Milk (the complete food) can be taken. Milk is rich in calcium, Vit D3, potassium, zinc etc. Cow milk is one of the best milks available. Milk nourishes every cell of the body. A glass of milk is a must every day. It provides all nutrients. Lactose intolerants must avoid consuming milk.
  • Basil leaves, tulsi, sacred basil, holy basil can be put in tea. It is rich in iron, Vit A, C, proteins. With many benefits from eliminating toxins to provide overall nutrition, Basil is amazingly helpful in various disorders as well including upper and lower respiratory tract disorders..
  • Bay leaves can be used in soups and stews. It is rich in potassium, Vit A, iron, calcium, phosphorus. It is commonly used in the kitchen in dried form. Thus consuming regularly never causes deficiencies.
  • Fenugreek seeds can be taken after soaking overnight. It is rich in phosphorus, potassium and has aphrodisiac action. It helps in digestive problems, improving cholesterol levels.
  • Turmeric can be taken as powder at night to combat inflammation and is a natural antiseptic and varnya (enhances skin lustre). It can be taken as turmeric tea or smoothie. It is rich in Vit B1, B2, C. Thus provides many nutrients which helps in many health issues.
  • Cinnamon powder can be sprinkled on food or tea can be prepared. It has Vit A, potassium and iron. It is rich in antioxidants, thus slows the ageing process and has  anti-inflammatory action. It also provides soothing action. It is helpful in tubercular ulcers. It has impeccable results in digestive disorders.
  • Ginger water or tea can be made or juice can be prepared. It contains potassium, iron, phosphorus, Vit A. It helps in inflammatory conditions, acts as a blood purifier, further aids anorexia and other digestion related issues.

AVAILABLE HEALTH SUPPLEMENTS

1. Herbal Supplements

These are easy to digest because they are natural, without preservatives and additives. They are pure. Thus they are maximally absorbed by the body because the body recognizes natural products.

2. Synthetic Supplements

Synthetic supplements are prepared in the laboratory. Because of this much of the dose is excreted without being completely absorbed. Most importantly, these may cause allergies in sensitive people.

HERBAL REMEDIES FOR NUTRITIONAL DEFICIENCY BY PLANET AYURVEDA

Planet Ayurveda is an Ayurvedic manufacturing company that makes its products purely from the plants. It has various branches overseas. Planet Ayurveda is GMP certified, USA-FDA registered and ISO 9001:2015 certified ayurvedic company. Products are made according to the ancient ayurveda texts. Products contain no additives and preservatives. Ingredients are pure without adulteration of any kind. Products do not have any side effects but may provide some side benefits.

  1. Vikramprash
  2. Immune Booster
  3. Daily Essentials
  4. Green Essentials
  5. Energo Plan Syrup

ayurveda multivitamin pack

PRODUCTS DESCRIPTION

1. Vikramprash

It is available in jam form. Ingredients are Bilva (Aegle marmelos), Agnimantha (Premna mucronata), Syonak (Oroxylum indicum), Patla (Stereospermum suaveolens), Pippali (Piper longum), Gokshura (Tribulus terrestris), Jivanti (Leptadenia reticulata), Utpal (Nymphaea alba), Musta (Cyperus rotundus) and other herbs. Drugs that are present in the formulation aids the well-being of the heart because it maintains cholesterol levels within normal limits. Antioxidants present in the medicine slow down the ageing process because it is rich in nutrients that rejuvenate body cells. Every day consumption enhances sexual behavior. It maintains digestive fire that leads to better absorption of nutrients/vitamins. It has anti-inflammatory action and acts as a tonic because it contains various herbs which are rich in multivitamins and other minerals. It acts as an immunity booster. Moreover it is helpful in various disorders.

Dosage: 1 teaspoonful twice daily after meals.

2. Immune Booster

Immune booster is a polyherbal capsule preparation with ingredients like Amalaki (Emblica officinalis), Bhumi amla (Phyllanthus niruri), Grape seed (Vitis vinifera) and some other herbs. Bhumli amla is best recommended for digestive issues which further helps in better assimilation of nutrients. It is beneficial in recurrent  urinary tract infection. Immune booster simply acts against diseases like cancer, asthma, infections etc. Ingredients themselves contain essential multivitamins. Multivitamins enhance immunity. Amalaki is a rasayana as per ayurveda texts that assists the overall well-being of a person.

Dosage: 1 capsule twice daily after meals.

3. Daily Essentials

Daily essential is a capsule preparation prepared using Ingredients like Green tea (Camellia sinensis), Bhumi Amla(Phyllanthus niruri), Grape seed (Vitis vinifera), Cow Colostrum (Bovine colostrums) and some other herbs. It has antioxidant properties that rejuvenates body cells. It boosts the immune system because it contains Cow colostrums. It is used in liver diseases because it has detoxifying properties. Ingredients themselves have multivitamins like vit A,E,K etc which also act as a multivitamin supplement. Moreover it is recommended for general weakness.

Dosage: 1 capsule twice daily after meals.

4. Green Essentials

The ingredients used in preparing green essential capsules are Wheat Grass powder (Triticum aestivum), spirulina (Spirulina Platensis) etc. It detoxifies the liver and also relieves stress. It aids digestion and balances all the doshas of the body i.e Vata, Pitta, and Kapha. It provides complete nourishment because of its enrichment in powerful nutrients. It boosts metabolism. It helps in diabetes and arthritis. It has anti bacterial, anti inflammatory, antioxidant properties. Excellent source of Vit A,C,B, K, E, iron, chlorophyll, 17 amino acids, phytonutrients, calcium.

Dosage: 1 capsule twice daily after meals.

5. Energo Plan Syrup

Ingredients of energoplan syrup includes Shatavari (Asparagus racemosus), Jeevanti (Leptadenia reticulata), Ashwagandha (Withania somnifera), Amalaki (Emblica officinalis),  and some other herbs. They contain Vit C, iron, calcium and other nutritious components. All the ingredients are Rasayana thus helps in overall promoting wellness. It fills a person with all basic nutrients. It keeps the mind, body, and soul peaceful and healthy.

Dosage: 2 teaspoons twice daily after meals.

CONCLUSION

It becomes important that in order to stay physically and mentally healthy, one must have access to nutritious food that must have proper essential vitamins and minerals. Herbal and natural supplements can help to combat nutritional and vitamin deficiencies and are way better because of their organic nature and origin providing all the essential requirements of nutrition. Moreover they boost immunity and overall well being. Planet Ayurveda is strictly adhered to the objective to provide pure herbal medicines and supplements. In case of any query kindly visit www.PlanetAyurveda.com. For more queries, you can send your queries to our email id herbalremedies123@yahoo.com.