Category: Cancer

Herbal Remedies for Progessive Supranuclear Palsy Treatment

ABSTRACT

Progessive supranuclear palsy is a uncommon brain disorder that causes difficulty in walking, eye movement, and balance. The brain is an organ made up of a large number of nerve tissues that is protected within a hard structure known as the skull. It mainly includes functions such as it helps in regulating blood pressure and breathing, releases hormones and processes sensory information. Brain health is an emerging and growing concept that provides plasticity, functioning across life.

Numerous interconnected social and biological genetics play an important role in normal functioning of the brain. The cerebrum is the largest part of the brain and divides into 2 hemispheres. Each hemisphere is divided into regions called lobes. There are 4 lobes- Frontal lobes, parietal lobe, temporal lobe, occipital lobe. There are many conditions affecting the brain such as Cerebrovascular injury such as strokes, Neurodegenerative disorders such as Parkinson’s disease, dementia, and many more. It includes symptoms like headache, dizziness, speech problems, seizures, dilation of one or more pupils. We will study about its causes, symptoms, and its ayurvedic aspect further in this topic.

INTRODUCTION

Progessive supranuclear palsy is a degenerative disease which involves the deterioration of the brain cells which further causes loss of balance, slowing of movements, difficulty in moving eyes. The cause of this disease is unknown but there is accumulation of a protein called Tau within the brain. Sometimes it can be misdiagnosed with Parkinson’s disease. This condition keeps on worsening over time. Neurodegenerative refers to the collapse of the nervous system where there is death of numerous cells. Supranuclear refers to damage to localized nuclei in the brain. It is also known as Steele Richardson Olszewski syndrome. It worsens over time and leads to life threatening conditions such as pneumonia, swallowing problems. Supranuclear refers to the region of the brain above 2 small areas called nuclei. It is more commonly seen in men than women and it affects the middle aged or older people.

Progessive Supranuclear Palsy

CAUSES

  • Progessive supranuclear palsy occurs mainly when brain cells are damaged resulting in buildup of protein known as Tau.
  • Tau occurs in the brain and usually breaks down before it reaches a high level.
  • In people who are suffering from Progessive supranuclear palsy the build up protein doesn’t break down and forms harmful clumps in the brain.
  • Clumps of tau are progressively seen in neurodegenerative disorders such as in Alzheimer’s disease.
  • Mitochondrial dysfunction can also cause progessive supranuclear palsy.
  • Substantia nigra is the most affected part of the brain where palsy symptoms are visible.
  • Clumps formed in the brain cells damages the neurons

SIGNS AND SYMPTOMS

  • Change in behavior such as irritability
  • Slurred speech
  • Difficulty in swallowing
  • Muscle stiffness
  • Loss of balance while walking- Tendency to fall back is an early symptom of this disease.
  • Depression
  • Dizziness
  • Rigid facial muscle
  • Urine incontinence
  • Sleep disruption
  • Constipation
  • Poor eyelid function
  • Contracture of the facial muscles.
  • Dementia

COMPLICATION

  • Falling which could lead to fractures, brain injury.
  • Difficulty focusing your eyes
  • Problems during inhaling food or liquid into the airway (aspiration).
  • Pneumonia which is the most common cause of death in progessive supranuclear palsy.
  • Impulsive behavior

TYPES

It is divided into following categories

  1. Classical Richardson syndrome
  2. Progessive parkinsonism and Progessive supranuclear palsy -pure akinesia with gait freezing
  3. Progessive supranuclear palsy – C
  4. Progessive supranuclear palsy induced by Annonanceae (known as custard apple)

DIAGNOSIS

  • Progessive supranuclear palsy diagnosis is difficult as it has signs and symptoms similar to Parkison disease. So doctor suspect following:
  • Don’t have tremors
  • Unexplained falls
  • Response to parkinson medication
  • MRI (magnetic resonance imaging)

TREATMENT

  • Parkisnson’s disease medications- It increases the level of brain chemical which controls the muscle movements, the effectiveness of this medication is temporary lasting for 2-3 years. Medications include- Levodopa, Levodopa with anticholinergic agents. 
  • Onabotulinumtoxin A- Is injected in small doses into muscle of your eyes as botox helps muscles to contract which improves spasms of eyelid.
  • Prism lenses- These lenses are very helpful as they ease the problems with looking downwards. These lenses allow people to look downwards without rolling their eyes downwards.
  • Physical therapy- It helps to improve balance, facial exercise, Gait balance and training helps to relieve symptoms of progessive supranuclear palsy.
  • Mental health- It is counseling with a therapist who improves the copying technique.
  • Antidepressant medications- The most commonly antidepressant medications are- Fluoxetine, Amitriptyline (Elavil).
  • As progessive supranuclear palsy worsens, the patient can’t swallow which prevents him/her from eating and drinking so surgery is recommended (GASTROTOMY).  

AYURVEDIC MANAGEMENT

Progessive supranuclear palsy is caused due to vitiated vata dosha. Vata dosha is responsible for control of all the nervous functions in the body. Vata dosha is a tantra which runs the machine of our body. When vata dosha gets disturbed it drives the body crazy, disturbs the events in the body and causes diseases. Vatavyadhi is divided into 2 parts- Dhatukshayajanya avastha pain is reduced by touching. But in Margavrodhajanya pain is aggravated after touching. Due to intake of vata aahara and vihaar, vata dosha gets vitiated which gets stuck in the rikta strotasa and loses their qualities like smoothness and stickiness. On occupying the srotas this vitiated vata will produce Ekanga and Sarvanga diseases. Two pathology plays an important role in vatavyadhi there is decrease in dhatu and srotas become empty, but in margavarodhjanya vatavyadhi there is obstruction due to dhatu, maal and vata dosha gets stagnated which leads to dysfunction in organs. 

CAUSATIVE FACTORS OF VATA VYADHI

  • Intake of dry food, cold food.
  • Improper administration of vamana, virechana.
  • Fear
  • Irritation
  • Excessive consumption of spicy foods.

PREMONITORY SYMPTOMS

  • Stiffness of joints
  • Horripilations
  • Lameness
  • Sleeplessness
  • Numbness in body parts
  • Convulsions
  • Pricking type of pain.

TREATMENT

  • Snehan
  • Swedan
  • Mridu shodhana (virechana)
  • Deepan and Pachana sneha
  • Massage with medicated oils
  • Hot and fresh foods
  • Pouring of medicated oil in the form of seka
  • Consume sour, sweet food

HERBS USEFUL FOR PROGESSIVE SUPRANUCLEAR PALSY

  • Turmeric- Turmeric (Curcuma longa) rectifies the metabolic fire due to its ushna veerya which further cleanses and detoxifies the ras, enables free circulation to each part of the body and restores the normal functioning of the body. Haridra removes the blocked channels and enables the free movement of vata and makes dhatu nourished and replenished.
  • Shilajit- Shilajit plays an important role in treating urinary disorders, skin disease, worms infestation, mental disorders. Shilajit plays an important role as it has fulvic acid which is preventing Tau protein from aggregating so it is useful in Alzheimer’ disease and is reducing anorexia. It helps to maintain blood pressure, strengthens the skeletal system, brings energy and stamina.
  • Amalaki- Amalaki is the best anti-aging herb which balances all the three doshas in the body, useful in bleeding disorders, fever, and has a rejuvenative property.  It is rich in vitamin C and antioxidants which nourish the tissues. Amalaki promotes healthy circulation, tonify the muscles, enhances memory and brings a sense of calm to mind. It clears and detoxifies the system known as Rasayana herb.

HERBAL REMEDIES BY PLANET AYURVEDA FOR PROGESSIVE SUPRANUCLEAR PALSY

Ayurvedic medicines treat the disease as the root cause for maintaining a healthy life. Planet ayurveda is a brand which has been serving pure extract in the form of tablets, capsules, powder which are prepared under guidelines of Ayurvedic board. The medicines prepared are free from any chemicals and preservatives, are 100% pure and vegetarian. Ayurvedic medicine reduces the risk of recurrence of disease and causes no side effects of the treatment as it is pure plant based extracts.

PRODUCTS LIST

  1. VRIHAT VATCHINTAMANI RAS
  2. MUSLI STRENGTH
  3. YOGRAJ GUGGUL
  4. ASHWAGANDHA CAPSULE
  5. NOURISH MAXX
  6. BRAHMI CAPSULE
Herbal Remedies for Progressive Supranuclear Palsy
Progressive Supranuclear Palsy

PRODUCTS DESCRIPTION

1. Vrihat Vatchintamani Ras

Vrihat vatchintamani ras is one of the classical formulations which is effective in balancing vata dosha. It is prepared in the form of tablets by planet Ayurveda using ingredients like- Swarna bhasma (Calx of Gold), Rasa Sindoor (Red sulphide of mercury), Praval bhasma (Calx of coral) and many more. These tablets are helpful in maintaining cardiac health by strengthening the muscles, used in a variety of diseases like diabetes, splenomegaly, hypertension. This tablet has rajata bhasma  which is an excellent drug for mental health disorders and has antidepressant property. 

Dosage– 1 tablet twice daily to be chewed with plain water after meals.

2. Musli Strength

Musli strength is a great formulation prepared by planet ayurveda in the form of capsules using ingredients like- Safed Musli (Chlorophytum borivilianum) Gokshura (Tribulus terrestris). It helps in strengthening of the body and bone, uplifts the power of the reproductive system as it increases the quality and quantity of sperms. It has gokshura which is a diuretic and has cleansing properties on the urinary system and on lithotriptic activity. Tribulus has wound healing properties and balances tridosha.

Dosage– 1 capsule twice daily with plain water after meal

3. Yograj Guggul

Yograj guggul are herbal tablets formulated by planet ayurveda using ingredients like- Guggul (Commiphora mukul), Amalaki (Emblica officinalis),Cardamomum (Elettaria cardamomum), Rasna (Pluchea lanceolata), Chitraka (Plumbago zeylanica) and many more. It is a useful preparation used in the treatment of splenomegaly, abdominal tumours, bone marrow, and increases digestion power. Yograj guggul is widely used in treatment of rheumatoid arthritis and gout.

Dosage– 2tablets twice daily with lukewarm water.

4. Ashwagandha Capsules

These are single herbals capsules formulated by planet ayurveda using standardised extract of Ashwagandha (Withania somnifera). Ashwagandha has rejuvenating that helps to maintain proper nourishment of the tissues. These capsules are useful in back stiffness, muscle fatigue, and have the property of balancing vata dosha in the body as vata dosha governs all the movement in the body. Ashwagandha has antioxidant, immunting enhancing, anti stress, rejuvenating properties. It inhibits inflammation and improves memory.

Dosage– 1 capsule twice daily with plain water after meals.

5. Nourish Maxx

Nourish maxx is a herbal powder preparation formulated by planet ayurveda using various ingredients like- Shatavari (Asparagus racemosus), Ashwagandha (Withania somnifera), Gokshura (Tribulus terrestris), Safed musli (Chlorophytum borivilianum). It helps to nourish the entire body, useful for both males and females, natural protein supplement for weight gain, bodybuilder, short height. Helps to maintain proper functioning of the organs. This powder has ashwagandha which helps to maintain and help the body to adapt to various types of stress.

Dosage– 1 tsp twice daily with normal water.

6. Brahmi Capsule

Brahmi capsules are single herbal preparation which is formulated by planet ayurveda using standardised extract of Brahmi (Bacopa monnieri). Brahmi is the best brain tonic which wonderfully works on brain health, promotes the regeneration of cells of the brain , so very helpful in Progessive supranuclear palsy, Alzheimer’s disease. It shows a miraculous effect on the liver as it removes the toxins from the body and promotes the functioning of the liver. Brahmi is useful in irregular menstruation, impotence, premature ejaculations, helps to relieve and prevent stress.

Dosage– 1 capsule twice daily with plain water.

CONCLUSION

Progessive supranuclear palsy is a uncommon brain disorder that causes difficulty in walking, eye movement, and balance.  The cause of this disease is unknown but there is accumulation of a protein called Tau within the brain.Vata dosha is responsible for control of all the nervous functions in the body. Further we studied its purva roop and many herbal remedies to cure this vata vyadhi. Planet Ayurveda also prepared many formulations which are useful in this disease without any side effects and maintained a healthy lifestyle for future needs. 

Efficacy of Dostarlimab in Treating Cancer & How Ayurveda Helps in the Management of Cancer

Abstract

Cancer is a life threatening disease in which the body cells of a particular part of the body grow uncontrollably and if remain untreatable, starts spreading to the other parts of the body. It can start anywhere in the body and is formed up of trillions of cells. In normal division the body cells grow and multiply to form new cells for further growth and when the cells become old they get degenerated and the new cells replace their place. But when the old degenerated cells do not vanish properly they remain in the site and start accumulating then they convert into tumors that may be benign or cancerous. The cancerous one invades into other cells and metastasis occurs with which they start spreading in the whole body. The benign growths do not get invaded and they don’t spread. Throughout the years for this cancerous growth there is not such evident cure but now there is a drug named Dostarlimab which comes with this efficacy. Let’s discuss dostarlimab in detail and how Ayurveda helps in promoting the management of cancer.

Dostarlimab

Introduction

Dostarlimab is a drug basically used for endometrial cancer that is considered as a mismatch repair deficient in those patients whose cancer is returned and the spread is not removed with surgery. This is given to those patients who already received the anticancer medications that had not worked well. Dostarlimab is considered a monoclonal antibody which changes the immune system to assist in controlling the growth of cancer cells. This drug is available in solution form and can be given only by the supervision of the doctor. Let’s discuss this drug in detail.

How Dostarlimab Works

Dostarlimab is also known as TSR-042 , a type of immunotherapy known as monoclonal antibody. These antibodies work by attaching to the protein known as PD-1 that is on the surface of the cancer cells. By attaching to this protein it assists the immune system evaluating, recognizing and then attacking the cancer cells.

Precautions to be Taken Before Usage

Before using this drug it is must to weigh the risk of the drug usage against the good this drug will do. The following points is to considered before the usage of this drug

  • Certain Allergies: It is must to tell the doctor if you ever had any kind of allergy previously to any medication. Must tell about your other allergies such as food allergy, allergy from preservatives, dyes, animal products, etc.
  • Pediatric and geriatric: It is must to evaluate the age of the patient before using dostarlimab as there is not any evidence of this drug in pediatric and geriatric age groups.
  • Breast feeding: The studies revealed that in breastfeeding mothers the administration of Dostarlimab shows harmful effects in infants. So if you are going to use this drug in breast feeding it is must to stop breastfeeding at the time.
  • Drug  interactions: There are certain medications that are not being used at the same time but certain can be used at the same time. In these cases the doctor must change the dosage and some other precautions to be taken at that time. The patient must have to tell the physician about any of the present prescriptions one is taking at the time of administration of Dostarlimab.
  • Some other interactions: Some of the drugs are not used with certain food or some other items such as alcohol or tobacco. So you must tell your doctor about these types of things if you are taking them.
  • Share about your other medical conditions: The existence of various medical problems may influence the use of this medicine. So it is important to tell your doctor if you are facing any of the medical conditions. Mainly the following:
    • Diabetic ketoacidosis
    • Colitis
    • Hyperthyroidism
    • Hepatitis
    • Nephritis
    • Pneumonitis
    • Immune system problems
    • Any organ transplant

How to use Dostarlimab Properly

A trained health professional or a nurse is there for administering Dostarlimab. This medicine is given by placing a needle into one of the veins. The speed must be slow while administering and the needle must be stable at that time for at least 30 mins. This will be repeated after 3 or 6 weeks, depending upon the dosage.

Precautions to be Taken After Administration of Dostarlimab

After getting the dosage of Dostarlimab it is a must to check your progress with your doctor on a regular visit to see how the drug is working in your treatment. To avoid unwanted effects you must go for your blood and urine profiles. Getting this medicine while pregnant will harm the child so it must be avoided at the stage of pregnancy. Must use birth control things while taking a treatment and after tht for at least 4 months. After taking the dosage you must tell your doctor if you are facing any kind of breathing difficulty, cold, cough or any respiratory issues. Beside this must take care of the following points after administration of Dostarlimab

  • There may be a chance of colitis (inflammation of colon), so keep in mind if you are facing stomach pain, fever, watery stools, bloody stools, etc and must tell your doctor about this urgently.
  • If you are facing symptoms such as pain in the upper abdomen, dark urine, pale stools, nausea, loss of appetite, yellow skin or eyes, etc. must visit your doctor as there may be a chance of serious liver disease.
  • A continuous headache, lightheadedness, changes in mood, fainting, dizziness, increase in weight. Must notice these symptoms as these are the symptoms associated with endocrine glands.
  • Dostarlimab may affect your blood sugar levels and it is a must to evaluate the regular blood sugar or urine tests.
  • If someone is concerned with symptoms such as cloudy or bloody urine, vomiting, nausea, swelling of the face, trouble breathing, unusual tiredness or weight gain. Must notice these symptoms to avoid serious kidney diseases.
  • Serious skin reactions may cause after the administration of this drug, so mst visit a doctor if you get peeling, blistering, loosening of the skin, itching, chills, skin, diarrhea, cough, sores, skin rash, ulcers on skin, swollen glands and other associated conditions with skin.

So these are some conditions that a person should keep in mind after the administration of Dostarlimab and if you notice any of the symptoms you must visit your doctor on an urgent basis. As we studied earlier, Dostarlimab has a lot of side effects so it’s better to take herbal remedies for the management of the cancer. Let’s discuss how Ayurveda works miraculously in the management of cancer.

What are the Alternatives for Dostarlimab in Ayurveda

Cancer is considered as the constant battle all around the world along with various developments in preventive and curative therapies. As we read earlier this condition is characterized by continuous and abnormal cell multiplication in any part of the body and our body is unable to control the growth. Currently the treatment in modern science includes chemically derived drugs, chemotherapy, radiotherapy, etc. Such type of  treatment puts the patients under stress and later on damages the health of the affected one. We are here with the alternative of these treatments that is with the holistic science – Ayurveda. Ayurveda heals a diseased person with natural and herbal medicines that do not have any kind of side effects on the body. So let’s discuss some of the herbs that aids combating this life threatening condition that is cancer.

Herbs Aids in Combating Cancer

  • Ashwagandha (Withania somnifera): This herb is very effective in relieving cancerous growths in the body. It is an immune boosting herb and consists of antioxidant properties which prevents the growth of cancerous cells anywhere in the body. Also consists of pro-oxidants which assists in attacking the cancer cells. This herb effectively protects non-cancerous cells from being affected with cancerous cells. Ashwagandha prevents the process of angiogenesis that is the formation of new blood vessels that is the main cause of promoting cancerous growth.
  • Kachnaar (Boerhavia diffusa): Kachnaar is one of the best herbs in the field of ayurveda for preventing any abnormal growth in the body. It consists of miraculous kapha pacifying properties and assists the management of cancer as cancer is the kapha predominating disease. Kanchnaar has a wonderful cytotoxic effect which inhibits cell growth as well as kills the abnormal growth. The antimitotic property of this herb prevents the further growth of the cancerous cells by reducing the cell proliferation.
  • Guduchi (Tinospora cordifolia): Guduchi is a tridosha balancing herb and considered as effective in improving the overall health. It helps in increasing the white blood cells that boost up the body’s defense mechanism. Basically this herb effectively builds up the strength of the person by its rejuvenating properties. It nourishes the seven bodily tissues and keeps the whole system in balance. So we can add guduchi to increase the immunity of the body and assist the good management of cancer.
  • Guggul (Commiphora mukul): Guggul is a resin consisting of antioxidant and anti-inflammatory properties that effectively aids in the management of cancer. In cancer there is a predominance of kapha dosha so by balancing the kapha dosha it prevents the further cancerous growth. The antioxidant properties prevent the formation of free radicals that are one of the causes behind initiating the cancerous growth.
  • Curcumin (Curcuma longa): Curcumin is one of the best antioxidant herbs among various antioxidant herbs. It is considered as anticancer in nature, effectively it aids in killing the cancer cells as well as stops the tumor growth and prevents the formation of new blood vessels that is the main cause of promoting cancerous growth.

So these effective formulations assist in preventing cancerous growth depending upon the stage of the cancer, age of the patient and many other factors. Planet Ayurveda provides a special crab care pack prepared by these herbs which can be a good alternative for Dostarlimab.

Crab Care Pack by Planet Ayurveda – Best Alternative for Dostarlimab

Planet Ayurveda is a GMP certified clinic which formulates their own remedies for almost all the health conditions. All the formulations are prepared under the strict observance of M.D. Ayurveda practitioners. The remedies are free from any kind of additives, color, resins, gums, preservatives and any kind of synthetic material. As the remedies are 100% pure so they can be used without worrying about the side effects. For the purpose of management Planet Ayurveda provides with a crab care pack which includes the following formulations:

  1. Ashwagandha Capsules
  2. Curcumin Capsules
  3. Kanchnaar Guggul
  4. Tulsi Capsules
  5. Guggul Capsules
  6. Chandraprabha Vati

crab care pack

All these formulations assist in the management of cancer due to their effective properties. These formulations consist of miraculous kapha pacifying properties that effectively reduce the cancerous growth as kapha dosha is mainly responsible for any growth in the body. The immune boosting properties of the herbs boosts up the immune system and improves the strength in the body to fight against the cancerous cells. The herbal formulations prevent the process of angiogenesis that is the formation of new blood vessels that is the main cause of promoting cancerous growth. So these are the properties which make the herbal remedies in Crab care pack effective for the management of cancer. Beside this crab care pack some other medications will be added with these one after evaluating properly the age of the patient, the stage of the cancer, area affected by cancer and various other factors.

Conclusion

Cancer is a life threatening disease in which the body cells of a particular part of the body grow uncontrollably and if remain untreatable, starts spreading to the other parts of the body. Throughout the years for this cancerous growth there is not such evident cure but now there is a drug named Dostarlimab which comes with this efficacy. Dostarlimab is a type of immunotherapy known as monoclonal antibody which is attached to the protein known as PD-1 that is on the surface of the cancer cells and assists the immune system evaluating, recognizing and then attacking the cancer cells. Before using this drug it is must to weigh the risk of the drug usage against the good this drug will do. Dostarlimab has a lot of side effects so it’s better to take herbs for the management of the cancer such as guggul (Commiphora mukul), ashwagandha (Withania somnifera), kanchanar (Boerhavia diffusa), giloy (Tinospora cordifolia), curcumin (Curcuma longa), tulsi (Ocimum sanctum) and various other. By these herbs Planet Ayurveda formulates a special crab care pack for combating cancer. Beside this crab care pack some other medications will be added with these one after evaluating properly the condition of the patient. So you can start taking these remedies without worrying and if you feel any query you can drop a mail on herbalremedies123@yahoo.com. For more details about our product, you can check our website www.PlanetAyurveda.com