Author: Dr. Vikram Chauhan

Abstract

In this article our main topic of discussion will be a very rare genetic disorder known as chaple syndrome. As there are some diseases that require early interventions, as if not treated in initial stages they might progress into serious outcomes. With ayurveda we can surely manage the disease progression by using basic principles of ayurveda. Ayurveda deals with such ailments by going into the depth of dosha imbalance. Vata, pita and kapha are the main principle energies of our body.

Ayurveda is an ancient healing system which was originated in India over thousands of years ago that focuses on balance of body and mind by considering the “tridosha’s theory” (3 most important energies in the body- vata, pitta & kapha) or “panchamahabhuta theory”[5essential component for life— akash (sky), vayu (air), agni (fire), jal (water),  prithvi (earth)]. If they are in their balanced state then works as prime fuel to control body functions, but once their existence gets adulterated either raised or decreased, it will lead to formation of a hazardous illness. So let’s start discussing this ailment in a more delineated manner.

Introduction

It is a very rare genetic disorder which sometimes appears as a multisystemic genetic syndrome. Chaple stands for CD55 deficiency with hyperactivation of complement, angiopathic thrombosis and severe protein losing enteropathy. This disorder generally occurs during early stages of life i.e. in children and can be life threatening. In this there is cross activation of the coagulation system, making individuals suffer from severe thrombosis.CD55 means complement decay-accelerating factor, it is a protein that plays major role in regulating complement system, this system is a part of immune system of our body that will enhance the properties of antibodies and phagocytes cells to clear out damaged cells from the body by enhancing healthy wound healing. In this there is severe protein losing enteropathy that leads to the formation of hypoproteinemia.

Ayurvedic overview on chaple syndrome

As per ayurveda we can correlate this genetic disorder with “anuvanshik vikar” (hereditary disorder) and it seems to occur due to the presence of pathology in beej bhag (chromosomes) and beej bhag avyava (genes).

ETIOLOGICAL FACTORS

These are the main causes (nidan as per ayurveda) that results in formation of an ailment.

• Genetic involvement- as it is considered to be an autosomal recessive disorder.
• Hereditary factor- Sometimes there seems to be the involvement of hereditary factors in this.

According to Ayurveda

There is an involvement of imbalance between the tridosha (three principle energies of our body- vata, pitta and kapha).

Other Important Causes of Such Disorders are

• Presence of deformity in mother’s ovum and father’s sperm.
• Intake of unwholesome diet by a pregnant lady.
• Deformity in the beej bhaag (chromosomes) and beej bhag avyava (genes)

Clinical Features

It includes the signs and symptoms. A symptom means the general complaints along with patients present in front of the physician

Signs

It means what a physician notices himself by observing the patient’s condition

• Nausea and vomiting
• Anorexia (loss of appetite)
• Diarrhea
• Weight loss
• Indigestion
• Polydipsia (increased thirst)
• Swelling
• Inflammation
• Bruising

Diagnosis

It means how we can identify the disease. There are various methods

• General physical examination of patients by using inspection, palpation, auscultation and percussion technique
• Proper history taking

Laboratory Findings

It includes

1. Complete blood count test.
2. Bone marrow examination.
3. Histopathological studies
4. Genetic testing

Management

As there is no definitive treatment of this ailment in modern systems of medicine they will just use a symptomatic approach that only gives temporary relief to the patient. So it is very important to follow basic principles of ayurveda, as ayurveda is just not a system of medicine but it is a way of life. It teaches us about the ideal lifestyle measures. By following them we can surely prevent ourselves from such genetic disorders as ayurveda works very generously by going into the root level of cause.

As per Ayurveda

We can use sanshodhan and sanshaman chikitsa in this, as these two treatment modalities focus on going into the root level of disease, and eliminating pathogens from its main residing seat. Thus these two hold key importance in ayurveda, firstly with sanshodhan chikitsa we will detoxify the body and then in detox.

A. Sanshodhan Chikitsa (Detoxification Procedure)

• Sanehan- Smoothing the body dosha’s by using herbal ghrit/oil.
• Svedan– Semi-hot medicated kwath is sprayed on the patient’s body by a specially made swedan yantra (instrument).
• Vaman (emesis) – emetic medicines are given to the patient to take out the vitiated dosha of the body.
• Virechana (purgation) is the best technique to release out the pitta dosha from      the body by anal route.
• Raktamokshan (bloodletting) -It is considered as “ardh chikitsa” (important as a whole treatment) by acharya shushruta because it helps in purifying the blood by removing harmful toxins from it.

(B). Sanshaman Chikitsa (Alleviating Treatment)

• In this treatment modality we use the herbal medicines by oral route to balance vitiated doshas within the body itself.
• In our ancient classical text the following medications should be used

1. Rasa/bhasma/pishti

• Shankh bhasma
• Praval bhasma
• Praval panchamrit

Dosage: 125-250 mg with honey/water.

2. Churna

• Laksha churna
• Ushiradi churna
• Aatrushakadi churna

Dosage: 3-6 grams with plain water.

3. Kwath/asav

• Aatrushakadi kwath
• Padmakadi kwath
• Lodhrasava

Dosage: 20-30 ml with plain water after meals.

If you want to use herbal formulations, Planet ayurveda a leading herbal manufacturing unit serving people worldwide with their herbal and authentic products offers various herbal formulations for this and are as follow

1. Ashwagandha Capsules

This herbal capsule contains standardized extract of ashwagandha (Withania somnifera). It is posse’s ‘breehmaniya’ (bulk promoting property) helps in increasing the body weight along with that it has antioxidant properties that will boost up the immune system and helps to develop strong immunity power to combat the pathogens in chaple syndrome.

Dosage: 2 capsules twice daily with plain water.

2. Punarnava Mandur

This herbal formulation is imbued with plenty of therapeutic actions as it contains punarnava (Boerhaavia diffusa) which is very effective in increasing the digestive power of the body. Other herbs present in the formulations such as

• Pipali (Piper longum)
• Sunthi (Zingiber officinale)
• Amalaki (Emblica officinale)
• Haridra (Curcuma longa) etc

Contain anti-inflammatory antifungal properties so it helps in healthy wound healing in patients of chaple syndrome.

Dosage: 2 tablets twice daily with plain water.

3. Immune Booster

This herbal capsule contains

• Grape seed (Vitis vinifera)
• Cow colostrums (Bovine colostrums)
• Bhumi Amla (Phyllanthus niruri)
• Amalaki (Emblica officinalis) etc.

All these herbs help in maintaining a healthy digestive system, circulatory system, healthy skin of individuals so manifest very beneficial in chaple syndrome.

Dosage:  1 capsule twice daily with plain water.

4. Wheatgrass Powder

This herbal powder contains pure form of wheat grass (Triticum aestivum). Wheat grass contains numerous health benefits as it boosts the metabolism that helps in regulating normal functioning of the immune system of our body. It also contains great blood purifying properties that help in removing harmful toxins from the blood so this proves a very efficacious blend in patients suffering from chaple syndrome.

Dosage: 1 tsf twice daily with plain water.

5. Pitta Balance

This potent formulation is an efficacious blend of praval pishti (coral calcium), akik pishti (Agate calcium), jawar mohra pishti (an ayurvedic calcium compound), giloy satva (stem extract of Tinospora cordifolia) etc. Minerals and herbs present in it have sheet virya (cold potency) thus works very well in reducing elevated pitta dosha within the body and elevated pitta dosha is considered as the main culprit of chaple syndrome.

Dosage: 1 capsule twice daily with plain water

6. Swarna Basant Malti Ras

This herbomineral formulation contains properties like anti-inflammatory (reduce inflammation). It helps in boosting up the immunity of our body by balancing tridosha. It also possesses “rasayan” property that rejuvenates the body channels and helps in lengthening the lifespan of chaple syndrome patients. It contains marich (Piper nigrum), kharpara bhasma (calamine in an incinerated form), shuddha hingula (cinnabar in a purified form), swarna bhasma (gold in an incinerated form) etc.

Dosage: 1 tablet twice daily with plain water.

Conclusion

Now we can conclude that with ayurvedic herbs we can surely prevent the complication of chaple syndrome very efficiently, if we consume herbal formulation in adequate amounts as guided by the physician along with proper dietary regime. Ayurveda offers numerous magical herbs that work quite efficiently in increasing the platelets count in a healthy way. It also teaches us about the principles of dinacharya (daily regime) and ritucharya (means seasonal regime). So you can choose planet ayurveda for the ayurvedic treatment. It is a leading manufacturing unit serving people worldwide by using basic principles of ayurveda. You can directly visit us at our clinic in Mohali Punjab or can send your queries on herbalremedies123@yahoo.com