Tag: Process of Hemapheresis

Ayurveda relation of Hemapheresis with Raktashodhana

Abstract

Hemapheresis is the process of selective collection of any blood component, with the use of automated equipment. In this process components of blood ie: RBC, WBC, plasma and platelets are removed from the patient ‘s body to achieve patient health and provide relief in symptoms. These diseases are not completely prevented but the symptoms and conditions are manageable. Let’s discuss Hemapheresis in detail about Hemapheresis.

Hemapheresis

Introduction

In the process of hemapheresis there is a removal of whole blood from the body of the donor. It is the process by which one or more components are withdrawn from the blood and returned by transfusion of remaining blood to the donor. Hemapheresis is considered as a supportive treatment for auto-immune and blood disorders. In auto-immune disorders the body produces antibodies which attack its own immune system and create infection in the blood. Ayurveda produces some of the great herbs and therapies which are very effective in cleansing the blood, in which leech therapy is very important. Rakta shodhana and Rakta mokshana are the procedures that are involved in hemapheresis. The blood is alive, contains living cells and is the fluid of health, transporting disease fighting substances to the tissue and waste to kidneys. The components of blood ie. red blood cells and white blood cells are responsible for nourishment and cleansing the body, blood also carries the oxygen to all body parts. When the body grows, it faces toxins, environmental pathogens and contaminated food by which the blood gets infected which causes the blood disorders.

Process of Hemapheresis

In this process the blood is taken from the donor’s body and then blood is removed from the donor’s body through a needle. Removed blood is mixed with the anticoagulant and separated in separators which works on the centrifugation process. Where the desired component is separated and the blood is returned to the donor’s body results in the filtered plasma.

The components which are separated are

  • Leukocytes (leukapheresis)
  • Plasma (Plasmapheresis)
  • Platelets (Plateletpheresis)

Leukapheresis: White blood cells (leukocytes) are removed from the patient’s body if the patient is suffering from a disease like thrombosis.

Plasmapheresis

Plasma is the important component of the blood and contains antibodies and antigen- antibody complexes which may contribute to effects of autoimmune disorders. Plasma removal helps in reducing the circulating antibodies and immune complexes. In case a large amount of plasma is removed, the plasma from a healthy donor is given to the patient which is called plasma exchange.
Plateletpheresis: This is very rare like: Myeloproliferative disorders, platelet count can be very high. Removal of platelets is helpful in Platelet removal and can help to avoid complications of thrombosis and bleeding.

Indications of Hemapheresis

Indications of Hemapheresis are

  • Malaria
  • Leukocytosis
  • Sickle cell disease
  • Liver transplantation
  • Familial cholesterolemia
  • Lung transplantation
  • Wilson disease
  • Hemolytic disease of foetus
  • Inflammatory bowel disease
  • Thrombocytosis
  • Myasthenia gravis
  • Kidney transplantation
  • Aplastic anaemia
  • Dermatomyositis
  • Systemic amyloidosis
  • Burn with circulatory shock
  • Acute liver failure
  • Dilated cardiomyopathy
  • Multiple sclerosis
  • ABO- Incompatible hematopoietic solid organ transplantation
  • Chronic inflammatory demyelinating polyneuropathy
  • Auto-immune hemolytic anaemia
  • Age-related macular degeneration
  • Amyotrophic lateral sclerosis
  • Coagulation factor inhibitors
  • ABO- Incompatible hematopoietic stem cell transplantation

Ayurvedic Overview of Hemaphereis

In Ayurveda blood is known as rakta and a very important component of the human body, disorders of blood cause prolonged and chronic disease. Acharya Shusruta who is known as father of surgery considered Rakta as a fourth dosha, mainly three doshas are the base of the body ie. Vata, Pitta and Kapha but Acharya Shusruta has also described Rakta as a fourth dosha. In Ayurvedic perceptive when doshas contaminates the blood it results in blood disorders which in ayurveda is called as Rakta Pradosaja Vikara, and there are many rakta-pradosja vikara and their modern co-relation which are as follows

  • Pleeha (Splenomegaly)
  • Vidhradi (Abscess)
  • Pama (Scabies)
  • Kamala (Jaundice)
  • Neelika (Hyperpigmentation)
  • Arsha (Piles)
  • Asya paka (Stomatitis/ Mouth ulcers)
  • Mashaka (Elevated moles)
  • Shwitra (Leucoderma/vitiligo)
  • Charamadala (Dermatitis)
  • Kotha (Urticaria)
  • Tilkalka ( Black Moles)
  • Vyanga (Freckles)
  • Visarpa (Herpes)
  • Indralupta (Alopecia)
  • Asru Dhara (Menorrhagia)
  • Kushtha (Leprosy)
  • Guda pak (Inflammation of anal canal)
  • Raktapitta (Bleeding disorders)
  • Vatashonit (Gout arthritis)
  • Medhra paka (Inflammation of penis)
  • Arbuda (Tumours)
  • Piplu (Port wine mark)
  • Gulma (Abdominal tumours)

Ayurveda Relation of Hemapheresis with Raktashodhana

Hemapheresis is related with Rakta Shodhana (purifying blood) and Rakta mokshana in Ayurveda and raktashodhana is the process which is used to purify the blood by using various herbs. There is also another process by which the vitiated Rakta is balanced which is known as Raktamokshna (bloodletting). Now we do not have to confuse rakta shodhana and rakta mokshana, both the processes are quite different. Purifying the blood through the herbs and natural remedies is called Rakta shodhana and where the toxins are very high and Rakta shodhna is not enough, in that case Rakta mokshana is used. Herbs which are used in Rakta shodhana are as follows

Effective Herbs to Purify the Blood

  • Guduchi
  • Haridra
  • Manjishtha
  • Neem
  • Sariva

Guduchi (Tinospora Cordifolia)

Guduchi is very useful in the aggravation of Tridoshas (Vata, Pitta and Kapha) , has anti- inflammatory properties and gives relief from the pain. This herb plays a great role in conditions of worm infestation, gives relief in jaundice, and increases the blood cells. Guduchi is very effective in chronic fever, in skin disorders and also reduces the weakness.

Haridra (Curcuma Longa)

The herb pacifies the Tridoshas and purifies the blood and is useful in preparation of the Red Blood cells. Haridra contains antiprotozoal, antiseptic and anti-inflammatory properties and useful in anaemia, leprosy haemorrhage and diabetes etc.

Manjishtha (Rubia Cordifolia)

Manjishtha pacifies the vitiated rakta and contains properties like: anti-inflammatory, antipyretic and anti protozoal. The herb is very effective in leprosy and in wound healing. It purifies the blood completely and acts as a rasanya and also gives relief from stress. The herb is very effective in female reproduction, contains diabetic properties, boosts the stamina and removes the toxins.

Neem (Azadirachta Indica)

Neem contains various properties and is helpful in many problems, it mainly pacifies the Pitta dosha due to its soothing and cooling effects. This herb is used in healing of the wound, abscess, blood disorders, alopecia, itching and greying of the hairs.

Sariva (Hemidesmus Indicus)

Sariva is useful in pacifying all tridoshas, has anti-inflammatory properties and contains a cooling effect. Sariva acts as a rasayana and is diuretic, it increases sexual activity and also increases fertility. The herb contains blood cleansing properties and is helpful in conditions like: syphilis, elephantiasis and leprosy etc. This herb is very useful in digestive problems and also acts as a diuretic.

Rakta Mokshana Therapy

Acharya Sushruta has described raktamokshana as a type of panchkarma. Rakta mokshana is used when there is a presence of high toxins and rakata shodhana is not enough. Some of the natural sources (ie. Instrumental and non-instrumental) used in this therapy are

Instrumental (Shastra)

Siravedha and Pracchan (Vein puncturing)
Non- instrumental (Anu-shastra): Alabu (Pitcher gourd), Jaloka (Leech therapy) and Shrunga (Cow’s horn method)
Instrumental

Siravedha (Venepuncture)

This procedure is very useful in destroying the disease from the root. Venepuncture in Shalya tantra is considered as the half complete therapy for numerous diseases as blood is the pathogenic factor in most of the diseases.

Prachana (Blood Letting by Puncturing)

In this procedure torniquet is applied slightly above the affected area and multiple incisions are made by using the sharp instrument and avoiding the vital structures. The incisions are not made very deep, superficial, should not be done transversally and are made very quickly in the upward direction.

Non- Instrumental

Alabu (Blood letting through pitcher guard)
The process is used in aggravated Kapha dosha and pacifies the aggravated Kapha dosha. In this procedure, small incisions are made on skin and after that the pitcher guard made hollow within, creating vacuum pressure by lighting the diya. Now the guard is kept at incised skin through blood is sucked by vacuum pressure, thus doing blood letting.

Jaloka (Leech Therapy)

This is the most important therapy in the raktamokshana and is a commonly followed procedure for blood letting. In aggravated Pitta vitiated rakta dosha this is very helpful as the leeches reside in the cold conditions. Jaloka is very useful in acne and skin disorders, the procedure is used in the patients who are scared from other bloodletting procedures.The saliva of leech contains the chemical Hirudin which is anticoagulant and prevents the blood from coagulation and inhibits the platelet aggregation and increase fluids and blood flow from the affected area. Leech only takes the blood which is vitiated and corrects microcirculation disorders. The therapeutic properties of this procedure are: it is immunostimulating, antioxidant, anti-inflammatory and atherosclerotic.

Types of Leech

There are mainly two types of leeches are considered ie. Poisonous and non- poisonous. Poisonous is called Savish and has 6 more types, non- poisonous is known as Nirvish contains 6 types. These types are described in (Sushruta Sutrasthana chapter/13 Sloka 11/12)

Poisonous (Savish Jaloka)

  • Krishna
  • Karbura
  • Algarda
  • Indrayudha
  • Samudrika
  • Gochandana

Non-poisonous (Nirvish Jaloka)

  • Kapila
  • Pingla
  • Shankh Mukhi
  • Mushika
  • Pundrikmukhi
  • Saavrika

Shrunga (Blood Letting Using Cow’s Horn)

In this procedure the selected cow’s horn is collected which is open at both ends, this is mainly used in Vata vitiated rakta. Small and multiple incisions are made over the affected area. The one side of the horn is placed at the incised skin and from the other side suction is created by the mouth which leads to blood letting. This procedure can be compared with cupping therapy.

Conclusion

Hemapheresis is the process used in vitiated blood, as our body grows the blood gets affected by various types of environmental factors and by toxins. In Hemapheresis one or more components are withdrawal to achieve the health of the patient. Vitiated blood causes in many blood disorders ie, Rakta pradosja vikara, in blood disorders it is very important to purify the blood. Ayurveda includes two main therapies ie. Rakta shodhana and Rakta mokshana and the bloodletting therapy by leech is one of the most easy and beneficial procedures in the Rakta mokshana. The procedures which are given in this article only remove the vitiated blood from the body. The herbs which are described here are used to pacify the blood and also provide strength to the immune system and have no side effects.

Process And Ayurvedic Aspect of Hemapheresis

Abstract

Blood is the main component of our body. It contains living cells like Red blood cells, White blood cells, and Platelets. Blood is responsible for the transport of oxygen and other substances in the whole body. But many causes can lead to blood infections and ultimately several diseases. Infection in the blood can be of any single blood component from plasma, lymphocytes, RBCs, WBCs, or a mixture of many of these blood components. Infected blood will cause infection in the whole body, and each organ, in short wherever the infected blood will reach the body, the area gets prone to infection and other diseases. To deal with such conditions Hemapheresis is performed to collect specific components for transfusion and remove pathogens from the infected blood or blood components. In the following article, we will discuss all aspects of Hemapheresis and similar aspects of blood cleansing in Ayurveda.

Hemapheresis

Introduction

Hemapheresis is the therapeutic elimination of blood components by passing the blood through automated equipment. Hemapheresis is a combined term used for various types of pheresis. Like plasmapheresis is the removal and replacement of a patient’s blood plasma, erythropoiesis is the removal and replacement of a patient’s Red blood cells, leucopheresis is the removal and replacement of a patient’s leukocytes, plateletpheresis is removal and replacement of patient’s of platelets, lymphopoiesis is removal and replacement of patient’s lymphocytes. These all are nonsurgical therapies for the removal and replacement of a particular blood component.

Process of Hemapheresis

Hemapheresis works on the centrifugal principle. The blood from the patient’s body is processed in the equipment where the components of blood are separated, the infected/target blood component is removed from the blood. After the removal of a particular component rest of the blood is returned to the patient’s body.

Indicators of Hemapheresis

  • Autoimmune diseases
  • Aplastic anemia
  • Acute liver failure
  • ABO-incompatible disorders
  • Macular degeneration
  • Multiple myeloma
  • Blood clotting disorders
  • Hyperviscous syndrome
  • Leukapheresis is performed when the number of leucocytes exceeds – in leukemia
  • Polycythemia
  • Liver, kidney, and lung transplantation
  • Hemochromatosis
  • Hemosiderosis etc

Ayurvedic Aspect

Blood is called Rakta in Ayurveda. The disorders of Rakta are known as Rakta Pradoshaj Vikar, which occur due to an imbalance of tridosha in the body. The Rakta disorders described in texts vary from skin, liver, and anas to the whole body.
Skin disorders such as Rakta Pradoshaj Vikar – Kotha [urticaria], Dadru [tinea], Charamdal [dermatitis]. Kushth [leprosy, psoriasis], Shavitr [leucoderma], etc.

Some other body diseases listed in Rakta Pradoshaj Vikar are – kamala [jaundice], vidridhi [abscess], arbud [tumors], indralupt [alopecia], raktpitta [bleeding disorder], arsh [hemorrhoids], pleeha vikar [splenomegaly], vatashonit [gout], etc.

In Ayurveda practice, 2 methods are practically used to purify the blood

  • Raktshodhana (Blood cleaning/purification)
  • Raktmokshana (Bloodletting)

Let us have a detailed look at the procedure of these two methods and know how successful these methods are working in blood purification

1. Raktshodhana [Blood purification]

Cleaning the blood is known as Raktshodhana. This is a commonest practiced method for cleaning blood in Ayurveda. Various herbal medication combinations are used to clean the blood. Likewise hemapheresis these herbs clean the blood, but inside the body itself. Blood-purifying herbs include – Haridra (Curcuma longa), Neem (Azadirachta indica), Sariva (Hemidesmus indicus), Manjishtha (Rubia cordifolia), Guduchi (Tinospora cordifolia).

2. Haridra (Curcuma longa)

The antiseptic, anti-inflammatory properties of Haridra acts as a blood purifier. It also helps in increasing the Red blood cell count in the blood. This herb is used internally as well as externally on wounds, and skin disorders due to blood toxicity. This herb cleans the blood internally by removing the infection (bacteria, protozoa) and also alleviates the pain.

3. Neem (Azadirachta indica)

Neem is the most known herb for skin cleansing and blood purification. It pacifies Pitta dosha due to its cooling properties. As this herb will clean the blood thus, will help in the recovery of diseases due to blood toxicity – syphilis, and diabetes. In addition, it recovers skin conditions like acne, dadru, skin rash with itching, etc.

4. Sariva (Hemidesmus indicus)

These herbs have various uses, and due to their blood-cleansing properties it is used in skin-related problems. It is a Rasayana and is used for digestive issues and increasing body metabolism. It also has anti-inflammatory properties thus used accordingly for various related disorders.

5. Manjishtha (Rubia cordifolia)

Manjishtha is commonly used as a Blood purifier. It is used in the treatment of several skin problems. It has anti-cancerous properties and helps to reduce any lumps in the body. Anti-diabetic and anti-stress properties of manjistha aid in healing the body. Along with it, manjishtha also has anti-inflammatory, anti-diabetic, and antioxidant properties.

6. Guduchi (Tinospora cordifolia)

It is an anti-inflammatory herb. It is used in the management of leprosy and other blood disorders. Guduchi enhances memory and activates the immune system. Guduchi is a wonderful herb and helps to improve various diseases such as chronic fever, diabetes, arthritis, asthma, and respiratory problems.

7. Raktamokshana [Bloodletting]

Along with Raktshodhana, in some conditions, the Raktmokshana is also performed for better and faster results. Raktmokshana is stated as the fifth procedure of panchakarma therapy by some acharyas. The best season/ time to perform raktamokshan is Sharad ritu (Autumn). Likewise Hemapheresis can also be done with the help of certain instruments, but it includes natural things to be used as an instrument, not electric ones as in Hemapheresis. Various natural instruments/ methods have been described in the ayurvedic texts according to the patient’s condition and age.

Non-Instrumental Methods – Jaloka [leech Therapy]

  • Shringa [cow horn method]
  • Alabu [pitcher gourd]
  • Ghantiyantra

Instrumental Methods

  • Prachaan
  • Siravedh [Vein puncture]

Jaloka [Leech Therapy]

Bloodletting with the use of a leech known as Jaloka in Ayurveda, blood cleansing is done. Jaloka is used in Pitta dosha dushti diseases and is considered the best Anushashtra. These jalokas are used in various skin wounds to facilitate early recovery and get rid of infections. cleanses the blood up to Ek hast (one hand) deep. This method is used in soft-hearted patients who cannot tolerate vein puncturing and other methods. Fresh leeches are used for impure blood-sucking. Hirudin present in the saliva of leeches has anti-coagulating effects that prevent blood from coagulating. Whereas, Hyaluronidase increases the blood flow to the affected area. Leeches suck impure blood in the beginning and maybe pure blood after that. Also, some leeches are poisonous so the collection should be done carefully. This therapy is done under the observation of an Ayurveda expert.

Shringa [Cow Horn Method]

Shringa is used in Vata dosha dushti disorders because of its Ushan (hot), Madhur (sweet), and Sanigdh (glossy) properties. It cleanses the blood up to 10 angul deep. The basic shringa is of length 7 angul with a hole on both of its endings, with a larger hole at one side and a small hole at another end. After a small incision is made on the site of bloodletting, the shringa is placed on it with the larger hole end on the skin and the other end away from it. Due to the pressure created by the vacuum, the blood is sucked out of the area.

Alabu [Bitter Gourd]

It is used in Kapha dosha dushti vikaras (disorders) because of its katu (bitter), rooksh (dry), teekshan (sharp) properties. It cleanses the blood up to 12 angul depths. An incision is made on the skin and the area is made slightly rough to keep a diya (lighted lamp) on it and alabu is kept on it, the negative pressure created in it will do bloodletting. This is done generally for 10-15 minutes. After that jatyadi tel or any other medicated oil is massaged very light-handed on the area.

Ghantiyantra

Ghantiyantra or Ghatika is used in Kapha and Vata dosha dushti rogas. Aacharya Charak used this method in Gulam disease (collection of impure blood in the stomach). The ghada is used in the form of cups on the surface of the skin which will create pressure on the skin for bloodletting. This is correlated to Couping Glass Therapy done nowadays.

Prachaan and Siravyadh

Incision is made on the body surface/sira (vein), that causes bloodletting. This is a very delicate process and must be performed by a specialist under the guidance of an ayurvedic expert. Written consent is required to perform this procedure. The Vitals of the patient is recorded before and after the procedure. Any dramatic changes in the patient’s condition and vitals should be managed immediately. Temporary diet and lifestyle changes are done for the patient after raktmokshan.

Contraindications for siravedh

Shloka

Shloka

 

Siravedh is not recommended for people with

  • Vrish awastha (Old age patient)
  • Darpok (Coward)
  • Kas (cough)
  • Shwas (Asthma)
  • Pakshaghat (paralysis)
  • Garbhini (pregnant)
  • Krish (a very lean person)
  • Murshit (unconscious)
  • After panchakarma

Conclusion

It is important to clean blood according to the patient’s disease and age. Traditional medicine is a combination of skills, knowledge, and practices based on theories. Various natural methods are used in Ayurveda for this processing. Bloodletting with leeches and the Couping glass method is being widely practiced these days. For the treatment of any blood disorders mentioned above, do visit our doctors for natural and effective management. For more queries visit us at www.planetayurveda.com