Tag: Diagnosis

Herbal Remedies for Glanzmann’s Thrombasthenia – Bleeding Disorder

Abstract

Glanzmann’s thrombasthenia (GT) is an inherited blood clotting disorder which is characterized  by impaired function of specialized cells called as platelets that are essential for blood clotting (coagulation). The symptoms generally include abnormal bleeding and if left untreated for a long time can prove fatal. GT can be managed in a safe and effective manner with the help of Ayurvedic mode of treatment. In this article, lets’ know about this disease in brief and discuss Ayurvedic herbal remedies for the disease.

Introduction

Glanzmann’s thrombasthenia is a bleeding disorder which is characterized by spontaneous bleeding starting from birth. In Glanzmann’s Thrombasthenia a person tends to bleed easily, may also present with easy skin bruising, can have frequent nosebleeds (epistaxis) and bleeding gums. Such patients can present with purple or red spots on skin which are usually due to bleeding underneath skin or swelling caused by bleeding within tissues. People with this disorder tend to bleed a lot following injury or surgery. Females with Glanzmann’s Thrombasthenia have excessive bleeding during menses and bleed more than usual after child birth. This excessive bleeding can result in extreme blood loss and can be fatal.

Symptoms of Glanzmann's Thrombasthenia

Causes of Glanzmann’s Thrombasthenia

This condition is a result of gene mutation. The Mutation in ITGA2B or ITGB3  results in  this condition. This gene is responsible for making two parts (subunits) of receptor protein integrin alphallb/beta3. This protein is abundant on the surface of platelets. Platelets are the small cells which circulate in blood and are an important component for clot formation. During coagulation integrin helps the platelet to combine together. The clot formation protects the body after injury by sealing off the damaged blood vessels and hence bleeding stops.

The gene mutation results in the deficiency of integrin alphallb/beta3. Due to its deficiency the platelets cannot clump together thus resulting in prolonged bleeding.

In some cases of Glanzmann’s Thrombasthenia no mutation is seen in integrin alphallb/beta3. In such cases the cause for the condition is not known.

Types of Glanzmann’s Thrombasthenia

Type 1:  In this type people have less than 5 percent of integrin alphallb/beta3 levels. This is the most common type.

Type 2: In this type people have 5-20 percent of integrin alphallb/beta3 levels.

Variant type: In this type the body produces an adequate amount of integrin alphallb/beta3 but it is nonfunctional.

Symptoms of Glanzmann’s Thrombasthenia

The symptoms in this case include

  • Tendency to bleed starts right after birth or short time.
  • Purple or red spots on skin
  • Bleeding gums
  • Bleeding nose (epistaxis)
  • Excessive bleeding during surgery or after surgery.
  • Intermittent gastrointestinal bleeding resulting in melena
  • In women excessive menstrual bleeding
  • Excessive bleeding during childbirth and after childbirth
  • Intermittent uterine bleeding
  • Blood in urine
  • In severe conditions hemorrhage and this can be fatal.

Treatment of Glanzmann’s Thrombasthenia

In modern science there is no specific treatment for this condition. The treatment   includes preventive measures like protecting oneself from injuries in case to avoid blood loss, some antifibrinolytics drugs to stop excessive bleeding, blood transfusion, if required.

Planet Ayurveda is a herbal based drug manufacturer that makes products in strict adherence to the Ayurvedic texts. The various drugs that are being manufactured here are well collected from natural sources, then purified & then formulated into different preparations. These products are made under the supervision & vigilance of our expert Ayurvedic doctors by ancient time tested formulas.

Herbal Remedies for Glanzmann’s Thrombasthenia

Ayurvedic Medicines for Glanzmann’s  thrombasthenia

Planet Ayurveda offers following herbal drugs for the management of this disease

  1. Immune booster
  2. Giloy Ghan Vati
  3. Kumar Kalyan ras
  4. Green essentials
  5. Punarnava mandoor
  6. Spirulina capsules

Product Description

1. Immune booster

The immune booster capsules are made up by combining different herbs like bhumi amla (Phyllanthus niruri), amalaki (Emblica officinalis) etc. In production of these capsules standardized extract of bhumi amla, amalaki and other drugs are used. Bhumi amla is a blood purifier and also works on skin conditions. In GT it will work by purifying blood and reducing skin spots.  On the other hand, amalaki is the highest source of heat stable vitamin C which is excellent for boosting metabolism.

Dosage: Two capsules twice a day.

2. Giloy Ghan Vati

This vati uses standardized stem extract from Tinospora cordifolia plant. Medicinal effects of the plant are blood purification, antipyretic properties, anti-inflammatory effects as well as work on immune system enhancement. In GT it can help to reduce tissue swelling due to bleeding within tissues hence reducing skin spots.

Dosage: Two tablets daily.

3. Kumar Kalyan ras

The Kumar Kalyan ras is available in chewable tablet form especially for children with glanzmann’s thrombasthenia. This tablet has antipyretic properties, also used in persistent cough conditions, boosts metabolism and many more.

Dosage: one tablet twice daily (to be chewed) with honey.

4. Green essentials

This is a kind of Ayurvedic multivitamin capsules and can be used in GT as to avoid any kind of deficiency. The product contains wheatgrass which is a great source of iron, calcium, magnesium, amino acids etc. It also contains spirulina which is having a great antioxidant, anti-inflammatory and anti-allergic properties. Other ingredients are amla which is a great source of vitamin C, grape seed and green tea.

Dosage: one capsule twice daily.

5. Punarnava Mandoor

Punarnava mandoor has many ingredients like punarnava (Boerhaavia diffusa), mandoor (purified ore of iron), amalaki (Emblica officinalis), haridra (curcumin) etc. Punarnava in this formulation have anti spasmodic, anti-microbial and anti-inflammatory properties, mandoor is well known for its hematogenic and haematinic effects. This can be used in patients of GT to avoid deficiency of blood and other important minerals.

Dosage: Two tablets twice daily.

6. Spirulina Capsules

These capsules contain spirulina which is having great antioxidant, anti-inflammatory anti-allergic properties. Spirulina is also used in treating anemia. In GT this will help in maintaining normal blood levels in the body.

Dosage: 2 capsules twice daily.

Contact my assistant to provide you the costing/ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214030 Or Check Website – www.PlanetAyurveda.com

Conclusion

The products which are offered by Planet Ayurveda for the Treatment of Glanzmann’s Thrombasthenia are totally herbal which are and obtained from natural resources, so they help in treating the cause of the disease & side by side promoting immunity. These drugs also have lesser side effects as compared to the drugs/methods used by Modern medicine. However, it is advised that people suffering from Glanzmann’s Thrombasthenia should use these herbal products under the guidance of an expert Ayurveda practitioner.

How to Treat Hidradenitis Suppurativa with Ayurveda ?

Introduction

Hidradenitis suppurativa is a chronic skin condition characterized by recurrent boil or lump beneath the skin. It causes abscess and scarring on the skin. These usually appear where skin rubs together or near the hair follicles having sweat glands. Groin region, breast, buttocks, and armpits are mainly affected. Women are more prone to this disease. Hidradenitis suppurativa usually starts after puberty and may become worse over time. It can pose serious effects on day to day life and emotional well being.

Hidradenitis-suppurativa

Is Hidradenitis Suppurativa Contagious?

No, it is not contagious.

What are the sign & symptoms of Hidradenitis suppurativa?

  • It can affect one or multiple areas of the body at a time and symptoms may vary from mild to severe.
  • Blackheads in small pitted areas of skin.
  • Lumps or boils appearing on various areas of the body are very painful.
  • A boil may be pea-sized and firm which with time either disappear or rupture and pus ooze out of it for few hours or maybe days. This cycle continues either on the same area or somewhere else on the body.
  • The hard and painful lumps which appear may develop and enlarge under the skin for years.
  • Oozing and leaking boils or lumps heals very slowly and can lead to scarring.
  • These lumps or abscess may spread to the waistband, nape of the neck and inner thighs too.

What are the Various Stages of Hidradenitis Suppurativa?

It has three stages

  • Localized or single abscesses along with itching and discomfort.
  • Recurrent abscesses appearing in different areas of the body.
  • A severe widespread outbreak of the disease which can even obstruct lymph drainage, restrict movement leading to social isolation.

What are the Causes of Hidradenitis Suppurativa?

The exact cause of Hidradenitis suppurativa is not recognized. But there are some potential reasons which can prone a person to this disease.

  • Smoking and obesity both are associated with this disease as it can make symptoms of the disease worse.
  • There can be considered the role of sex hormone as this disease usually occur at puberty and is less common after menopause.
  • Hidradenitis runs in family so there is a role of genetic factors.
  • Environmental factors also play a role in the occurrence of this disease.

What are the Risk Factors to Develop Hidradenitis Suppurativa?

  • Age plays a major role as it usually occurs in early puberty and is less common after menopause and before puberty.
  • Women are more likely to develop this disease.
  • Family history increases the risk to develop the disease.
  • It can be associated with other conditions like arthritis, obesity, severe acne, inflammatory bowel disease, Crohn’s disease, diabetes, and metabolic syndrome.
  • Smoking also increases the risk to develop Hidradenitis suppurativa.

How can Hidradenitis Suppurativa Diagnose?

Diagnosing a rare disease like HS can be challenging. There is no definitive test for it yet. It can only be diagnosed by patient’s medical history, physical examination and laboratory test like swab test of the infected area.

What Complications can be of Hidradenitis Suppurativa?

  • The affected area can get infected.
  • Boils or abscess heals very slowly which leaves scars and marks behind.
  • When the abscess is in armpits or thighs it can cause soreness and restrict the movement of the part.
  • Obstruction of the lymph node is very common in this disease which can cause swelling of the legs, arms or genitals.
  • Due to the restriction of movements and bad odor from the boils can be the point embarrassment for the patient which can cause social isolation.
  • In rare cases patient with this disease can develop squamous cell carcinoma of the affected area.

How can Hidradenitis Suppurativa be Treated?

There is no exact cure or consistent effective treatment for Hidradenitis suppurativa in modern medicine. Management includes antibiotics and anti-inflammatory medicines and surgery is another method.

How does Ayurveda Explain Hidradenitis Suppurativa?

According to Ayurveda, Hidradenitis suppurativa is Kapha and pitta dosha. The faulty digestive fire (Agni), i.e. Pitta impairs metabolism and vitiates the Kapha Dosha. The fat molecules are impaired and start depositing in the muscles and block the channels of the body which causes painful swollen lesions in the groin region, buttocks, thighs, and armpits usually.

How is Hidradenitis Suppurativa Treated at Planet Ayurveda?

Planet Ayurveda offers various remedies that effectively help to treat Hidradenitis suppurativa. Medicines offered by Planet Ayurveda are 100% Ayurvedic, safe, free from chemicals or any kind of preservatives, and are not tested on animals.

1. Kaishore guggul

This remedy is very effective in various diseases. Kaishore guggul is an anti-inflammatory remedy which helps to relieve pain, swelling, and redness of the affected part. In Hidradenitis suppurative along with relieving inflammation, it will also clear the accumulation and prevent further collection of pus in boils/abscesses. This medicine regulates the metabolism and eliminates the toxins. It reduces lymphatic congestion.

Dosage :- Take 2-3 capsules twice a day after meals.

2. Gandhak rasayan

It is a natural supplement that rejuvenates the body. It will help to increase immunity and prevent infection in boils that are the main concern in Hidradenitis suppurativa. This remedy has antifungal, antibacterial, antitumor, anti-inflammatory and anti-diuretic properties as well which will overall help to treat and manage the condition of Hidradenitis patient. Gandhak Rasayana is a wonderful remedy to eliminate toxins from the body.

Dosage :- Take two tablets twice a day after meals.

3. Pitta balance

As we know there is a role of imbalanced Pitta dosha in Hidradenitis suppurativa so Pitta balance capsules will balance pitta and help to treat this disease. It relieves ulcers, piles, acidity, and bleeding gums. This remedy will purify the blood and nourishes the skin. Immunity is increased by consumption of these capsules.

Dosage :- One two capsule two times a day after meals.

4. Manjishtha capsules

These capsules are known to be a vigorous blood purifier, removes toxins from the body and enhances blood circulation. Along with blood it also cleanses the lymphatic system. It also has anti-microbial and anti-inflammatory properties. Healing properties of these capsules help to heal abscess in Hidradenitis suppurativa patient. Manjishtha capsules detoxify the body.

Dosage :- Take 1 to 2 capsules two times a day after meals.

5. Aller G care capsules

These capsules control acute and chronic allergies. It has anti-inflammatory and antibiotic properties which help to relieve inflammation and prevent or treat infections. Aller G care capsule has very good pain relieving effects. Anti-oxidant properties of these capsules help to eliminate free radicals from the body and improve body’s strength.

Dosage :- Take 1-2 capsules once a day after meals.

Other than these remedies there is some external application which helps to relieve the symptoms of Hidradenitis suppurativa.

6. Neem Oil

Apply Neem oil. It is anti-inflammatory in nature which relieves redness, pain, and swelling of the affected part. It has analgesic properties, relieves pain associated with abscess or other skin conditions. It moisturizes and nourishes skin. Neem oil has anti-bacterial properties, fights against bacteria and bacterial infections.

7. Royal honey shower gel

Wash abscess or affected area with this shower gel. Royal Honey Shower Gel deeply cleanses the body. It maintains the pH of the skin and keeps skin hydrated. This gel moisturizes and keeps skin overall healthy.