Tag: Crigler Najjar syndrome

Ayurvedic View On Crigler Najjar Syndrome & Its Treatment

Abstract

It is a very hard situation where a child is born with congenital defects. No one except the parents of the child can understand the pain that child goes through because of these congenital diseases. Medical science has evolved so much in the last few decades, but still there are some limitations that make it helpless in some cases. Today in our topic we are going to learn about one such disease, where a newborn has some congenital defects, that is Crigler Najjar syndrome.

Crigler Najjar Syndrome

Introduction Of Crigler Najjar Syndrome

Crigler najjar syndrome is a clinical condition which is characterized by severe unconjugated hyperbilirubinemia (convert and clear bilirubin from the body). This is so called as first described by Crigler and Najjar in 1952. It is a rare autosomal recessive disorder. This could result in bilirubin induced neurological disorder. There are broadly two types of Crigler Najjar Syndrome which are as follows:

Type 1 crigler najjar syndrome: This type of crigler najjar syndrome includes absence or minimal bilirubin-UGT1A1 activity. It starts in the neonatal stage that is right after birth till whole life. Patients with this type of crigler najjar syndrome are more prone to develop BIND (Bilirubin Induced Neurological Disorder). This is managed with daily phototherapy in order to maintain serum bilirubin in normal limits. This is the severe type of crigler najjar syndrome.

Type 2 crigler najjar syndrome: This is a less severe type of crigler najjar syndrome as it has reduced bilirubin-UGT1A1 activity.

Causes Of Crigler Najjar Syndrome

This happens because of a mutation in a gene that is known as the UGT1A1 gene. Genes are responsible for the manufacturing of the proteins which play important roles in the body. When there is an alteration or mutation in genes then the information for the production of proteins might be faulty. Therefore, in this case the mutation of UGT1A1 gene which hinders the proper conversion and excretion from the body.

Symptoms Of Crigler Najjar Syndrome

The symptoms of Crigler najjar syndrome are as follows:

  • Jaundice in neonates
  • Bilirubin encephalopathy also known as Kernicterus (A condition in which bilirubin gets accumulated in the brain, damaging the central nervous system)
  • Vomiting
  • Fever
  • Unsatisfactory feeding
  • Opisthotonus (a kind of posture due to spasms of the muscles which result in bending of heels and head backwards and body bows forward)

Diagnosis Of Crigler Najjar Syndrome

The diagnosis of the Crigler Najjar Syndrome is done with the help of genetic testing. This is a special technique and not available at every laboratory.

Treatment in Allopathy For Crigler Najjar Syndrome

Unfortunately, there is only management possible in allopathy which means with the help of aggressive phototherapy the unconjugated bilirubin is excreted through bile. In short, the scope of the treatment in allopathy for Crigler Najjar Syndrome is not promising.

Ayurvedic point of view On Crigler Najjar Syndrome

When we come across terms like mutation and genes then it seems that they have been discovered recently a century ago with the aid of a microscope. But this is not the case in Ayurveda. Even thousands of years before the discovery of the microscope Ayurveda gave descriptions of genes in ancient texts. Genes are referred to as “Beejbhaga” and chromosomes are referred to as “Beej” and parts of chromosomes as “beejabhagavayava”. Any abnormality (mutation) in the Beej Bhaga leads to genetic disorders like in this case of Crigler Najjar syndrome.

Planet Ayurveda is a leading firm which prepares natural herbs using authentic ways and has great results in curing Crigler najjar syndrome. All the herbs that are prepared here are free from chemicals, preservatives, starch, additives, colors, yeast, binders and fillers. They are 100 percent natural and are formulated by MD Ayurvedic doctors with years of experience. It has a worldwide range of distributors and has a great response from various countries when it comes to cure diseases that are considered incurable by allopathic doctors.

Products available at Planet Ayurveda for Crigler Najjar Syndrome

  1. Yakrit Plihantak Churna
  2. Phyllanthus Niruri
  3. Echinacea Capsules
  4. Liver Detox Formula

Herbal Remedies For Crigler Najjar Syndrome

1. Yakrit Plihantak Churna

It is a wonderful remedy for clearing the toxins from the body by supporting the liver. A very useful formulation by Planet Ayurveda for cirrhosis liver, fatty liver, jaundice which is because of damage caused by alcoholism. In the Crigler Najjar syndrome it is like a blessing as it promotes bile production and excretion. Ingredients of the Yakrit Plihantak Churna are Bhumi Amla (Phyllanthus niruri), Bhringraj (Eclipta alba), Kaasni (Cichorium intybus), Makoy (Solanum indicum), Kalmegh (Andrographis paniculata) and other herbs.

Dosage: You can boil the powder 1 teaspoonful in 400 ml water, keep it boiling until it remains 50 ml. Strain it and drink the water. Leave the residue. Do it twice daily. Make fresh every time.

2. Phyllanthus Niruri

This formulation of Planet Ayurveda is a great appetite stimulant. It will be helpful in all cases of Hepatitis of any type. In the malfunctioning of the liver it is a well indicated remedy. For fatty liver, hepatitis, liver enlargement and other liver disorders this formulation is inevitable. Its anti-hepatotoxic property makes it a favorite remedy to be recommended by physicians in cases of diseased liver for better functioning. Ingredients of Phyllanthus Niruri are Bhumi Amla (Chanca piedra).

Dosage: 2 capsules twice daily after meals with warm water.

3. Echinacea Capsules

For ones who have low immunity and catch cold easily, this is a permanent solution. The Indian Echinacea is also known as “king of Bitters”. It works well in cases of parasitic infections, viral infections and bacterial infection. Very useful in skin affections also. Ingredients of the Echinacea Capsules are Kalmegh (Andrographis paniculata).

Dosage: 2 capsules twice daily after meals with warm water.

4. Liver Detox Formula

It is an inevitable formulation for the detoxification of the liver. It will support the functions of the liver and increase the appetite. Apart from liver detoxification it has many other benefits like better control of blood sugar in a natural way. The long effects of the drug abuse could be easily eliminated with the help of this marvelous formulation of Planet Ayurveda. Ingredients of the Liver Detox Formula Capsules are Makoy (Solanum nigrum), Jhavuka (Tamarix gallica), Haritaki (Terminalia chebula), Punarnava (Boerhavia diffusa), Katuki (Picrorhiza kurroa) and other herbs.

Dosage: 2 capsules twice daily after meals with warm water.

Conclusion

We could conclude that there are several herbs mentioned in the ancient texts of Ayurveda which are capable of curing the Crigler Najjar Syndrome. For cases which seem incurable in modern science, Ayurveda has a permanent cure. At Planet Ayurveda the formulations are prepared strictly following the principles of ancient Ayurveda. This helps in getting good results in curing chronic diseases.

Treatment of Crigler Najjar Syndrome Type 1 in Ayurveda

If your child has been suffering from constant episodes of jaundice, it’s time to unravel the underlying cause.

Here’s Ayurveda for your empowerment!

Jaundice is most often misunderstood maturity of the world, it’s true it can occur as a result of disrupted habits of an individual but repeated episodes of this malady are no joke!. The term syndrome stands for a group of signs portrayed in the individual during a pathology. Crigler Najjar syndrome is a genetic condition where the liver loses its ability to break down bilirubin in the blood resulting in repeated episodes of jaundice in many individuals. Does it sound crazy? Let’s simplify it then!

A better Understanding

The liver is the site for all metabolic transformations of the body and this is the same site where the blood contents are destroyed. The blood hemoglobin is separated into iron and protein entities of which protein is further divided into bilirubin and biliverdin. The bilirubin is pushed into the alimentary canal and colors the stool. So when the bilirubin is not properly synthesized or its transportation is hampered it travels to all other areas of the body except the alimentary canal and causes color discoloration in skin mucosa causing jaundice. In Crigler Najjar syndrome,  the child is born with a gene defect where a proper breakdown is not initialized, also those who have persistent jaundice soon after birth are susceptible to this disease manifestation.

Here are the Signs and treatment

According to modern scientists, the condition is believed to manifest with genetic background. For this reason, the symptoms mostly experienced by the individual will be repeated jaundice-like presentations without any other associated complaints. Gene mutation is understood as the cause as well. Diagnosis for this condition is formed with a blood sample containing traces of bilirubin glucobilinoids in bile. Often a liver biopsy may also be suggested by your doctor.

Being a purely genetic manifestation, The treatment for this condition is achieved through symptomatic relief and dietary supplements that support liver function. For this oral or parenteral supply of heme oxidase inhibitors are supplied to reduce the load of bilirubin in blood.  With ample treatment methodologies in the market, the disease has a fairly good prognosis pattern, provided the condition does not deepen into kernicterus.

Crigler Najjar Syndrome Type 1

AYURVEDA’S ACTION IN THIS SYNDROME

Ayurveda, an age-old science of life, understands and comprehends a disease through the perspective of Doshas, the bodily entities that govern all the metabolic and mechanical functioning of the body. With our modern view on the functioning of the body, the treatment methodology of this branch of science might seem to be peculiar surely but it is effective.

Ayurvedic Pathophysiology

Here all disease formations are propelled into drastic seniors in the presence of an impaired digestive fire or Agni. In the Ayurvedic system of medicine, Yakrit or liver is the reservoir of blood tissue elements and also the site of localisation of the Pitta entity. With digestion and liver metabolism at stake, the pitta entity loses its control in the general metabolism and tends to flow freely with the vata entity resulting in discoloration throughout the body as jaundice. All immune-compromise maladies occur in the body due to compromised Ojas or coefficient of immunity, so is the condition here.

Thus the treatment protocol used in this field begins with medications that are digestive and carminatives that normalizes the pitta within the digestive fire. Later the pitta entity within circulation is brought back to the liver where it is metabolized using the rightful utility of specific detox therapies according to the condition of the patient. Further,the immune status of the body is normalized using rejuvenations that ensure fullon metabolic enhancement at all spheres of health.

PLANET AYURVEDA FOR YOUR SUPPORT

Here on planet Ayurveda we use the best herbal drugs right from nature’s basket to aid your wellbeing. We have thus introduced our liver care pack formulated to normalize the hepatic mechanisms of your body.

Herbal Supplements for Najjar Syndrome Type 1

Crigler Najjar Syndrome Type 1

1. Yakritplihantak Churna

This authentic formulation is composed of herbs that improve the general metabolism of the silver and ensure prudent liver cell regeneration during the normalcy of the organ. It is advised to consume this by preparing a decoction of 1 teaspoonful of the powder in 400 ml of water and reducing it into 50ml. Once cool you can strain and consume it twice daily or as recommended by your ayurvedic physician for better results.

Dosage– 1 tsp twice daily with lukewarm water

2. Phyllanthus Niruri

Ayurveda infers the importance for certain herbs with exceptional qualities against  a maldity, these are called Arge Aushada. One such Agre Aushadam for liver dysfunctions is BhumyAmalaki (Phyllanthus amarus). It contains many hepatoprotective phytoconstituents that ensures the optimacy for liver mechanism. Its hot potency which normalizes the digestive fire while its astringent flavour has the same metabolic end effect that normalizes the pitta entity as well.

Dosage-It is advised to consume 2 capsules twice daily after meals or as recommended by your ayurvedic health professional.

3. Echinacea capsules

The kalamegha or Andrographis paniculata is known as the king of bitters. It is a wonderful immune stimulant with wonderful restorative ability. It has the potential to normalize all systemic mechanisms of the body including liver metabolism.

Dosage-It is advised to consume 2 capsules twice daily after meals or as directed by your ayurvedic health care practitioner.

4. Liver Detox Capsules

If your liver is healthy, then your system is healthy. This mystic combination of herbs like Klamegha (Andrographis paniculata) and many others helps to normalize the functionality of the liver. It helps clean the liver and offers ample space for liver detox and rejuvenation.

Dosage-It is advised to consume 2 capsules twice daily after meals or as instructed by your ayurvedic physician.

While taking dietary supplements that support our well-being, Ayurveda strictly ensures that right dietary adaptations and lifestyle modifications must be incorporated to sustain our health. While this Indian science does not show results overnight, through adamant determination you are sure to reach your goals.

By imbibing in the goodness of this holistic science you are sure to restore your metabolic wellness and spiritual upliftment.

Contact my assistant to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214040 Or Check Website – www.PlanetAyurveda.com

Choose Ayurveda to reward yourself well-being!