Tag: Charcot-Marie-Tooth disease

Ayurvedic Prescpective Of Hereditary Motor Sensory Neuropathy(HMSN)

ABSTRACT

Hereditary motor sensory neuropathy commonly known as charcot marie tooth disease – is an inherited as well as progressive disorder. This condition is associated with the nervous system, the nervous system is the controlling center of the all body commands. It controls all the movements of the body and controls all processes of the body such as digestion, puberty, breathing and all other body processes. All the activities we perform, anything we feel, we say, all these are under the control of the nervous system. So if the nervous system is working properly then your whole body is healthy. But there are several conditions that are associated with the nervous system, among which one is HMSN disease, which is an inherited nervous disorder we are going to discuss in this article.

INTRODUCTION

Hereditary motor sensory neuropathy is an inherited nervous disorder that is also called as Charcot marie tooth disease. This disease is progressive in nature in which nerve cell deterioration is the main pathology. This concern is majorly seen in the legs and less commonly in the arms. The muscles of feet and hands get weak as the impulses towards these muscles are hampered. In addition to this there are a lot of symptoms to be faced that we will discuss further, so before studying the symptoms of HMSN let’s discuss the causes of HMSN.

CAUSES

There is no certain cause of HMSN, this disease is inherited. Chromosomes 1 and 17 seem to be affected chromosomes with mutation. It is inherited in autosomal recessive, autosomal dominant and the x-linked manner. Beside this there are some risk factors of HMSN such as Americans worldwide and in the generations children are more affected.       

Hereditary Motor Sensory Neuropathy

SYMPTOMS

The symptoms of HMSN can vary from person to person and it’s not possible to predict the age at which symptoms may appear. There are some early symptoms, main symptoms and later symptoms of HMSN, let’s discuss further.

Early symptoms of HMSN

In the early stages it is difficult to mark symptoms, they are usually evaluated when it gets worsened. Following are some symptoms that are noticed in the early stages:

  • Uncoordinated
  • Face difficulty while walking as the affected one may face problems with raising their feet up from the ground.
  • There is a kind of foot drop noticed, while lifting their feet the toes drops forward.

Main symptoms of HMSN

The main symptoms of HMSN are seen in the middle of 5-15 and the symptoms are not developed clearly until an affected one may lead to the middle or later ages. So below are the main symptoms of HMSN

  • Weakness of muscles in the legs, feet and ankles.
  • Feet are highly arched that leads to unstable ankle
  • Hammer toes (curled toes)
  • Lack of sensation in the feet and lesser than that in arms.
  • Poor blood circulation leads to cold hands and feet.
  • There is a wasting of muscles occurring in the lower legs that can lead to bottle shaped legs.

There are some additional symptoms that are noticed in some persons

  • Tremor (uncontrolled shaking)
  • Scoliosis (abnormal curvature of spine)
  • Dysphagia (problem while swallowing)
  • Difficulty while speaking
  • Difficulty breathing

Later symptoms of HMSN

As the HMSN proceeds to the later stages the weakness in the muscles and the sensation loss get worsened  that can start to affect the hands and arms the most. There is difficulty in performing even small tasks such as buttoning the shirt and performing day to day activities such as bathing, walking, sitting, etc. When they walk it puts strain on the muscles that further lead to joint and muscle pain. With growing age the mobility gets worse and a person may need an aid for walking.

DIAGNOSIS

The diagnosis of HMSN is done with the motor nerve conduction test and EMGs. A person to be diagnosed with HMSN should undergo a complete diagnostic and a clinical evaluation. The clinical diagnosis is done for the muscle weakness, atrophy and all types of sensory responses. For more clear diagnosis a blood DNA test is to be done.

AYURVEDIC VIEW OF HMSN

As we read earlier the HMSN is an inherited disorder, so as per ayurveda it is correlated with beeja dosha, which means the condition occurs with the defect in beejbhaga (sperm and ovum). Ashudh shukra and Ashudh artava (defected sperm and defected ovum) are considered as  the main causes of this condition. If there is any defect in the gametes (sperm and ovum) of parents then the child should inherit the disease. Beeja dosha due to the fact that if the mother conceived when her uterus or artava (gamete) is not totally vitiated but troubled by imbalanced doshas because of her improper diet intake. If there is any defect due to beej bhaga then cause beeja dosha and the deformity will occur in the fetus. As it is an inherited disease, we may manage the symptoms of the disease and there are some natural herbs that manage the symptoms of the disease and make the affected person’s life better by improving the quality of life.

HERBAL REMEDIES BY PLANET AYURVEDA FOR MANAGING HMSN

Planet Ayurveda is a GMP certified clinic which provides treatment for a wide range of diseases. All their remedies are formed under the guidance and supervision of M.D. ayurveda doctors and 100% purely vegetarian. Also while formulating their remedies they take care that any kind of added synthetic material should not be added to it like any sort of resins, fibre, colour, preservatives and all. For managing HMSN Planet Ayurveda listed 7 herbal remedies. Further we are going to discuss all about these herbal remedies and how it benefits the HMSN patients.

  1. ASHWAGANDHAGHAN VATI
  2. ATIRASADI CHURNA
  3. KUMARI SAAR
  4. TRIBULUS POWER
  5. MUSLI STRENGTH CAPSULES
  6. VRIHAT VATCHINTAMANI RAS
  7. NEUROGENIE CAPSULES

Ayurvedic Treatment For Hereditary Motor Sensory Neuropathy

Herbal Remedies for Hereditary Motor Sensory Neuropathy

PRODUCT DESCRIPTION

1. ASHWAGANDHAGHAN VATI

Ashwagandhaghan vati by Planet Ayurveda is a herbal remedy in tablet form which consists of a single herb Ashwagandha (Withania somnifera). As we discussed earlier the HMSN is an inherited disease so we can focus on managing the symptoms of the person and making the day to day life more ebay. So mainly the vata dosha is responsible for maintaining the neurological symptoms. Ashwagandha ghan vati helps in balancing vata dosha this helps in maintaining the symptoms of the HMSN.

Dosage: 2 tablets twice daily after meals with plain water.

2. ATIRASADI CHURNA

Atirasadi churna is the herbal remedy in powder form prepared by Planet Ayurveda. It consists of various balya (strengthening) herbs such as safed musli (Chlorophytum borivilianum), kali musli (Curculigo orchioides), gokshura (tribulus terrestris), shatavari (Asparagus racemosus), ashwagandha (Withania somnifera) and various others. This herbal remedy boosts up the overall strength of the affected person and helps in preventing muscle wasting, muscle strain, pain in the muscles and nerves, etc. Thus makes it easier to perform day to day activities.

Dosage: 1 tsp twice daily after meals with warm milk.      

3. KUMARI SAAR

Kumari saar is a herbal juice preparation formed by Planet Ayurveda with the help of juice extract of kumari (Aloe barbadensis) leaves. As we know the patients affected with HMSN need a perfect rejuvenation for leading a good quality life. This herbal remedy helps in providing that rejuvenating property to the patient and helps in boosting the immunity which makes the quality of life improved in the patient of HMSN.

Dosage: 2 tsp twice daily with plain water after meals.

4. TRIBULUS POWER

Tribulus power is a herbal remedy in capsule form that is formulated by Planet Ayurveda under the strict guidance of M.D. Ayurveda doctors. These capsules consist of pure herbal extract of gokshura (Tribulus terrestris) which contains various properties such as immunity-boosting and rejuvenating. So both these properties help in assisting the management of HMSN symptoms.

Dosage: 1 capsule twice daily with plain water after meals.

5. MUSLI STRENGTH CAPSULES

Musli strength capsules are available in capsules form and consist of standardized extracts of  safed musli (Chlorophytum borivilianum)  and gokshura (Tribulus terrestris). Safed musli is known for the rasayana (rejuvenates cells) and bruhmana (nourishing) properties. Gokshura consists of madhura rasa (sweet taste) which is  also nourishing in nature.   Both these herbs are very best in providing strength to the muscles and hence prevents the progressive muscle wasting in HMSN.

Dosage: 1 capsule twice daily with plain water after meals.

6. VRIHAT VATCHINTAMANI RAS

Vrihat vatchintamani ras is a classical ayurvedic formulation in tablet form. This is a herbo-mineral remedy which is prepared by Planet Ayurveda as per the method of preparation available in the classical texts. It consists of ingredients such as swarna bhasma (calyx of gold), rajat bhasma (calyx of silver), abhrak bhasma (calyx of mica) and various others. All the ingredients present in this ayurvedic formulation consists of miraculous vata balancing effects as the name suggests along with that it is balya in nature (strengthening) which provides strength to the muscles and nerves that alleviates the symptoms of HMSN.

Dosage: 1 tablet twice daily with plain water after meals.

7. NEUROGENIE CAPSULES

Neurogenie capsules by Planet Ayurveda consist of the standardized extract of Brahmi (Bacopa monnieri) and Ashwagandha (Withania somnifera). Brahmi (Bacopa monnieri) consists of antioxidant properties that aids in preventing the degeneration of the nerve cells thus restricting the further progress of the disease HMSN. Ashwagandha (Withania somnifera) contains wonderful rejuvenating and strengthening properties that help in managing the symptoms of HMSN such as muscle pain, difficulty in breathing, difficulty in lack of sensation, difficulty while walking, etc.

Dosage: 1 capsule twice daily with plain water after meals.

Contact Planet Ayurveda to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214040 Or Check Website – www.PlanetAyurveda.com

CONCLUSION

HMSN is an inherited disorder that is also called as Charcot marie tooth disease which is progressive in nature that includes nerve cell deterioration as the main pathology. . It occurs by the mutation (change) in the Chromosomes 1 and 17. In general the condition occurs due to transfer of defective genes from both the parents. According to Ayurveda HMSN is correlated to beeja dosha, which means the condition occurs with the defect in beejbhaga (sperm and ovum). Progressive muscle wasting, Severe disability, Disturbed gait, Decreased stability, Frequent falls, Difficulty in climbing stairs, Difficulty in walking, in short a person is unable to perform day to day activities. So if you are facing these issues, you must choose ayurveda treatment. It will improve your quality of life and make you better to perform day to day activities. For this purpose Planet Ayurveda is there for you with a miraculous list of herbal remedies, then stop worrying and start taking Ayurvedic medicine to improve your day to day life.

What is GNE MYOPATHY? – Causes, Diagnosis & Ayurvedic Treatment

Abstract

GNE myopathy is a hereditary illness that mostly affects the skeletal muscles. It is also known as HIBM, Nonaka myopathy, IBM2, and distal myopathy with rimmed vacuoles. The disease’s earliest symptoms develop between the ages of 20 and 40, and it affects both men and women at the same rate. Progressive muscular weakness, which often increases over time, decreasing grip strength, and frequent loss of balance are all symptoms of this illness. There is currently no cure for the condition, and therapy focuses on symptom management. Ayurveda, on the other hand, may aid in the management of this ailment.

Introduction

GNE myopathy is a hereditary muscle disorder in which GNE refers to the defective gene. It is a rare condition that affects around one person in a million individuals throughout the globe. It causes muscle weakness and atrophy in the legs and arms. The beginning of symptoms is generally in young adults, however, some people have seen a later onset. Foot drop is generally associated with increased tripping and a steppage gait at first. The problem worsens with time, resulting in proximal leg muscular weakness, difficulty ascending stairs or rising from a seated position and weakening of the hands and shoulder muscles.

How an you recognize myopathy’s indications and symptoms?

  • Disturbed gait and impaired stability are common in GNE myopathy patients, as are frequent falls, difficulties ascending stairs, jogging, and getting up from a sitting posture.
  • The muscles of the lower limbs are the first to be damaged, with the exception of the quadriceps, which seem to be largely unaffected.
  • Neck muscles might be impacted in the latter stages of the illness.
  • Finally, as the illness progresses, skeletal muscle function may be lost completely, leaving the patient completely reliant on others.

Acquired myopathies may exhibit symptoms that are comparable to hereditary myopathies, as well as the following

  • Muscle deterioration
  • Motor sluggishness
  • Impairment of the respiratory system
  • Dysfunction of the bulbar muscles (malfunction of the muscles responsible for swallowing and speech)

Causes of GNE myopathy

Causes

Changes (mutations) in the GNE gene, which codes for the enzyme glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase, cause GNE myopathy. Infection, muscular damage, medicines, electrolyte imbalances, and thyroid illness are among the other reasons.

Diagnosis

GNE myopathy testing is appropriate for patients who have foot drop (in young adults) and distal extremity muscle weakness (in those who have advanced stages of the illness). Genetic testing is an excellent initial step in determining the severity of GNE myopathy in individuals. This includes the use of minimum or no invasive treatments, simply requiring a blood or saliva sample, and yielding results in hours or days.

Factors at Risk

Some myopathies, such as some forms of muscular dystrophy, are hereditary. Other myopathy risk factors include:

  • Myasthenia gravis, scleroderma, and thyroiditis are examples of autoimmune diseases.
  • Endocrine problems
  • Toxin exposure, such as pesticides and flame-retardant chemicals
  • Infections
  • Deficiency in vitamins
  • Antihistamines and long-term corticosteroids are among the drugs used.
  • Glycogen and lipid storage disorders are examples of metabolic diseases.

Treatment with Ayurveda

It is considered an incurable myopathy, with mortality occurring between the ages of 20 and 25. Modern science has limits in treating the ailment, but Ayurveda has a lot of promise in treating diseases that are incurable. Ayurveda may assist in maintaining a healthy range of motion for all of the body’s joints. Toxins are removed from the body, the doshas are balanced, and the body cells and muscles are rejuvenated to promote strength and flexibility. Yoga and meditation sessions are used in addition to treatment methods to increase blood circulation to all body parts and joints. These reduce the likelihood of acquiring additional medical problems while also enhancing respiration and other critical bodily processes.

A healthy food plan is also arranged for optimal nourishment that assists in muscle growth as well as overall body development. A well-balanced diet may assist to soothe inflamed doshas and bring the body’s critical systems and hormone levels back into equilibrium. Herbal decoctions for internal ingestion are given in addition to therapy regimens to assist ease symptoms. And that’s what the world’s leading Ayurveda industry, Planet Ayurveda offers us.

Description of the product

1. Ashwagandha Ghrit

It’s great for muscular fatigue, stiffness in the neck or back, exhaustion, joint problems, and arthritis of any kind. It also helps with anxiety, tension, and depression. The main ingredient of this formulation includes Ashwagandha (Withania somnifera).

Dosage: 1 tsp twice a day in warm water

2. Musli Strength

Safed Musli (Chlorophytum borivilianum) and Gokshura (Tribulus terrestris) are used in this herbal medicine. It aids in the enhancement of growth hormone circulation in the blood. This also aids in the development of muscle growth and strengthening to help in reducing GNE myopathy effects.

Dosage: 1 capsule twice a day

3. Boswellia Curcumin

Boswellia Curcumin seems to be helpful in lowering inflammation, alleviating arthritis symptoms, and increasing muscular strength. Shallaki (Boswellia serrata) and Curcumin (curcuma longa) are the main ingredients in this herbal combination that can help to get relief from GNE myopathy.

Dosage: 2 capsules twice a day

4. Yogaraj Guggul

Yograj Guggulu contains herbs including Chitraka (Plumbago zeylanica), Shuddha Guggulu (Commiphora mukul), Ardraka (Zingiber officinale), Pippali (Piper longum), Haritaki (Terminalia chebula), and others that may help reduce pain and enhance joint and muscular mobility, which following useful to get rid from GNE myopathy.

Dosage: Take 2 tablets  twice a day

5. Atirasadi Churna

Gokshura (Tribulus terrestris), Ashwagandha (Withania somnifera), Nutmeg, Shatavari (Asparagus racemosus), Kali Musli (Curculigo orchioides), Safed Musli (Chlorophytum borivilianum), and Varahi Kand (Dioscorea bulbifera) are some of the components in Planet Ayurveda’s Atirasadi Churna. It primarily aids in the development of stamina, and the strengthening of weak muscles. Moreover, it helps in the reduction of tension, and the reduction of worry.

Dosage: 1 tsp twice a day with warm milk is the recommended dosage.

6. RasRaj Ras

It is an Ayurvedic medication for neuromuscular diseases, as well as nerve and muscle strengthening. Ashwagandha Churna (Withania somnifera), Rasa sindura (purified and processed Mercury), Swarna Bhasma (Gold Bhasma), Loha Bhasma (Iron Bhasma), Rajata Bhasma (Silver Bhasma), and Vanga Bhasma (Tin Bhasma) are some of the herbs found in it.

Dosage: 1 chewable tablet once a day.

7. Bala Ashwagandha Oil

The oil’s rejuvenating effects help muscles to relax, nerves to tone, and nerve conduction to improve. It is used to relax the muscles while gently stroking them.

Dosage: For external use only.

Contact my assistant to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214040 Or Check Website – www.PlanetAyurveda.com

Conclusion

The negative effects of long-term allopathic medicines and therapies that produce GNE Myopathy might be addressed with these herbal combinations. As a result of the inefficacy of allopathic therapy. Start with Planet Ayurveda to purchase a real Ayurveda product if you want to learn more about the therapy. They may be reached at herbalremedies123@yahoo.com or their clinic in Mohali, Punjab.