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Treatment For Progressive Multifocal Leukoencephalopathy (JC-Virus)

Abstract

PML is a brain disorder caused by JC virus. JC or John Cunningham virus is a common germ and half of all adults have been exposed to this virus. There is no way to keep yourself from getting it. This virus was first discovered in 1971. It affects the patient’s brain. This is a neurotropic virus that may bind to the cell surface of specific brain cell types. This is responsible for fatal demyelinating disease of the central nervous system which is known as PML. The John Cunningham virus has been detected in neurons, astrocytes and oligodendrocytes. In this article we are going to discuss PML and its Ayurvedic treatment.

Introduction

PML stands for Progressive-Multifocal-Leukoencephalopathy. This is a rare and fatal viral disease which is characterized by progressive damage or inflammation of the white matter or we can say that this is a disease of the white matter of the brain. This could be caused at multiple locations in the brain. This disease is mainly caused in those patients who are immune compromised and in those patients who have weak immunity. PML is an aggressive viral disease of the central nervous system. It attacks the cells that make myelin (fatty substance which coats and protects nerve fibers in the brain). This disease affects virtually any part of the body and also this is a life-threatening condition.

Etiology/Causes

This disease as discussed above is mainly caused by JC virus. This virus is normally present inside the body of the individual and kept under control by our immune system. If our immunity is strong then this virus will no longer cause any harm to the body. But if a person is immune compromised then this virus will show harmful effects  tinhe body. 

Other known causes are

Person who is suffering from AIDS

  • Immunosuppressive medications for longer period of time
  • Multiple sclerosis medications  
  • Autoimmune disorders

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Who will get this virus

There is no exact idea who is prone to this virus. But some known facts are

  • Children who are addicted to eat soil
  • Low immunity

Clinical features/Sign and Symptoms

Signs and symptoms can develop over several weeks to months and also depend on the location of damage in the brain. The person who is having PML will show the following symptoms

  • Clumsiness
  • Progressive weakness
  • Visual and speech changes
  • Personality changes
  • Facial drooping
  • Mental slowness
  • Loss of language skills
  • If this virus affects the parietal and occipital lobes of the brain then it can leads to a phenomenon which is known as Alien hand syndrome

Pathogenesis

As mentioned above, this disease affects the myelin sheath so it is known as a demyelinating disease. It damages the myelin sheath which covers the axons of the nerve cells, which further impaired the transmission of nerve impulses. It mainly affects the subcortical white matter, which is particularly present in the parietal and occipital lobe.

Diagnosis

This disease is diagnosed on the basis of progressive course of the symptoms of PML. Some diagnostic tests for this disease are

  • Lumbar puncture: This test is done for the diagnosis of this disease by taking samples of the spinal fluid and tested further for detecting JC virus antibodies.
  • Blood tests: Blood samples can reveal the presence of JC virus antibodies in the blood. 
  • Imaging tests: CT scan images show multifocal, non-contrast, hypo-dense lesions without mass effect. But MRI is more sensitive than CT scan. 
  • Brain biopsy: In this technique a piece of tissue is removed from the patient’s brain and examined under a microscope. 

Treatment

In allopathic medicine, there is no specific treatment for PML. No drug effectively treats the viral infection. The treatment aim is to reverse the immune deficiency to stop the disease progress. If a patient is using immunosuppressant drugs then stop the medications. This is the way to treat the PML by improving the immune system. One more thing we can do is via plasma exchange. This procedure will help in clearing the system by removing drugs that caused PML.

If a person is having PML due to HIV-AIDS, then we can use highly active antiretroviral therapy. This drug helps in reducing the viral reproduction.

Complications

This disease shows the following complications as this is a life threatening condition

  • Dementia
  • Seizures
  • Coma

Herbal treatment for Progressive multifocal Leukoencephalopathy

<span “>In Ayurveda there is a better treatment protocol for this disease. There are some herbal remedies for this disease. Planet Ayurveda provides the best herbal treatment for this disease. Basically this is a manufacturing company which manufactures several herbal products by using their standardized extracts. These products are made under the guidance of expert Ayurvedic physicians.

 Following herbal products are useful in PML disease

  1. Shilajit Capsules
  2. Boswellia Curcumin
  3. Musli Strength
  4. Giloy Capsules
  5. Memory Support
  6. Vrihat Vatchintamani Ras
  7. Neuro plan Syrup
  8. Energo plan Syrup

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Product Description

1. Shilajit Capsules

This is a single herbal formulation. These capsules are best for weakness due to any reason and these capsules are made from the standardized extracts of Shilajit (Asphaltum punjabianum). This is an effective anti-aging and a powerful rejuvenator. This is also the best antioxidant product. This herbal product provides good results in PMl disease. 
Dosage: 1 capsule twice a day with plain water after meals

2. Boswellia Curcumin

This is a poly herbal formulation. It is an effective combination of anti-inflammatory herbs. This combination is made by using the standardized extracts of Shallaki (Boswellia serrata) and Curcumin (Curcuma longa). This combination reduces inflammation and also helps in fighting against foreign bacterial and viral infections as it contains Curcumin (Turmeric) which has antiseptic properties. It also improves the overall joint health. 
Dosage: 1 capsule twice a day with plain water after meals

3. Musli Strength

These capsules are a poly herbal formulation. This product provides regenerative powers as it contains the standardized extracts of Safed Musli (Chlorophytum borivilianum) and Gokshura (Tribulus terrestris). These herbs are best for enhancing stamina. This product is useful in enhancing immunity as it is an Oja vardhak which is an immunity in Ayurveda.
Dosage: 1 capsule twice a day with plain water after meals

4. Giloy Capsules

This single herbal product is the best supplement for fever and immunity. This product is made by the standardized extracts of Giloy (Tinospora cordifolia). This is a wonderful antipyretic herb. It has anti-inflammatory properties also. This Ayurvedic herb helps in enhancing immunity of the individual. It also helps in the cases of infection. Giloy is an anti-arthritic, antipyretic and digestive.
Dosage: 1 capsule twice a day with plain water after meals

5. Memory Support

This poly herbal formulation of Planet Ayurveda is the best herbal supplement for central nervous system diseases. It helps to increase memory and overcome stress and anxiety. It is made by using the standardized extracts of Brahmi (Bacopa monnieri), Vacha (Acorus calamus), Shankhpushpi (Convolvulus pluricaulis) and licorice (Glycyrrhiza glabra). This product gives new life to dying brain cells and improves the body’s defense mechanism.
Dosage: 1 capsule twice a day with plain water after meals

6. Vrihat Vatchintamani Ras

This is a classical Ayurvedic formulation in a tablet form. This formulation is used in various Vata disorders. This formulation is made using the following purified compounds such as Swarna bhasma (Gold calx), Rajat bhasma (Silver calx), Abhrak bhasma (Mica calx), Mukta bhasma (Pearl calx) etc. This classical product is used in the treatment of paralysis, epilepsy, neuralgia, neuropathy etc. It is a good anti-aging medicine. It helps in reducing the symptoms of PML
Dosage: 1 tablet twice a day with plain water after meals

7. Neuro plan Syrup

This is an Ayurvedic medicine in a syrup form. This syrup is helpful in maintaining the health of the neurons. It boosts the memory and strengthens the nerve cells. This syrup is made by using wonderful herbs such as Brahmi (Bacopa monnieri), Mandukaparni (Centella asiatica), Shankhpushpi (Convolvulus pluricaulis), Jyotishmati (Celastrus paniculatus), Ashwagandha (Withania somnifera) etc. It balances the tridosha. This wonderful syrup helps in fighting against parkinsonism, dementia, cerebral atrophy etc. 
Dosage: 2 teaspoonful twice a day after meals

8. Energo plan Syrup

This formulation helps in boosting the energy of the body, as this disease causes weakness in the body. This herbal syrup has cooling, calming and soothing effects on the body. This herbal product is made from Jeevanti (Leptadenia reticulata), Amalaki (Emblica officinalis), Shatavari (Asparagus racemosus), Ashwagandha (Withania somnifera), Gokshura (Tribulus terrestris) etc. This is a natural energy booster. It strengthens the body and stamina quickly. 
Dosage: 2 teaspoonful twice a day after meals

Contact Planet Ayurveda to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214030 Or Check Website – www.PlanetAyurveda.com

Conclusion

We concluded at last that Progressive Multifocal Leukoencephalopathy disease is a life-threatening disease and could take away life if not treated timely and properly. As we can see that there is no proper treatment in Allopathic science for this disease. So its better to adapt Ayurveda for better treatment and for better prognosis. Ayurvedic treatment is not only treating the symptoms but also helps in treating the disease from its root cause. So Planet Ayurveda products show good results in this disease.

Hydrocele testis, Symptoms, Causes, Diagnosis & Ayurvedic Treatment

Abstract

Hydrocele is a condition in which there is accumulation of serous fluid in the body cavity. Hydrocele testis is a condition in which there is accumulation of fluids around the empty space of testicles. It is generally caused by the peritoneum wrapped around the testis. This peritoneum here is called tunica vaginalis. The hydrocele in primary form may develop in adulthood also, particularly in the people who are living in hot countries. The secondary hydrocele can develop as the result of some testicular condition like infection, tumor or sometimes infection also. In this article we will discuss the causes, types, symptoms, diagnosis and treatment of hydrocele.

Introduction

In the word hydrocele, hydro means water and cele means swelling. Hydrocele is understood as the condition in which a swelling is formed due to the accumulation of fluid around the testis. The swelling is usually painless and is present in the outermost covering of the testes. Urology explains that fluid space in the spermatic cord, due to the failure in closure of the tract through which the testis descends into the scrotum. The peritoneal fluid thus drains through this open tract and gets trapped in the scrotum. This condition can also be the result of a blow to the scrotum.

Due to the presence of ulcers, Ayurvedic drugs having vrana shodhana (purification of ulcers) and ropana (healing) properties are made use. Moreover Amapachana (removal of toxins) is done whenever required. Herbs like Lodhra (Symplocos racemosa), Musta (Cyperus rotundus) ,Arjuna (Terminalia arjuna) ,Vasa (Adhatoda vasica) and various others are best suited for this condition.

Hydrocele testis

Causes

Hydrocele can be produced by four ways

  1. It can be produced due to the excessive production of fluid in the scrotal sac.
  2. The scrotal fluid already contains some fluid for the nourishment of the testicular covering membrane. But if there is defective absorption of serous fluid then hydrocele occurs.
  3. Any condition like elephantiasis that interferes with the lymphatic drainage of social structures.
  4. It can also be associated with the connection to a hernia in the abdominal cavity.

Symptoms

Symptoms usually include heaviness in the groin region, scrotum enlargement, discomfort due to the large size of scrotum and pain as the size of the scrotum increases.

Types of hydrocele

Following are the types of Hydrocele

1. Primary hydrocele

The scrotal swelling in this case is soft and non tender and also appears large on examination. Testis are generally never felt during palpation or physical examination. Transillumination demonstrates the presence of fluid in the scrotum. They grow to a very large size if ignored for a long time. The Big size of the scrotum causes discomfort and also causes testicular atrophy. It is capable of obstructing the blood supply to the scrotum.

2. Secondary hydrocele

This type usually develops due to the associated testicular disease or condition like cancer, trauma or testicular inflammation. It is mostly associated with acute or chronic epididymo- orchitis. It is also associated with testicular torsion. It is lax and moderate in size with palpable underlying testis.

3. Infantile hydrocele

In infantile hydroceles the tunica vaginalis and the processus vaginalis are distended to the inguinal ring but usually have no relation to the abdominal cavity.    

4. Congenital hydrocele

This type develops due to the communication between the processus vaginalis and the peritoneal cavity. The communication is the result of failure of processus vaginalis to close.

5. Encysted hydrocele

It is understood as the smooth, oval shaped swelling near the spermatic cord which is usually understood as inguinal hernia. The swelling moves downward and makes the testis move gently downward. They become immobile once moved down.

Diagnosis

Transillumination test is positive and the fluctuation test is also positive. Impulse on coughing is negative and reducibility is also absent. On palpation testis are not palpated separately.

Treatment

When it appears in the first year of life it generally resolves on its own but if it persists even after the first year or occurs later in life then it requires treatment. If the case is chronic then it is recommended to go for surgery in which hydrocele sac is excised. One can also opt for aspiration, but this procedure is not that much effective because with increasing months the fluid usually gets accumulated again?

As per Ayurveda

In ayurveda hydrocele is understood as andavridhi (swelling in sac). The cause for this accumulation of fluid is vitiation of vata and rakta dhatu. The vitiation of these two can also be the result of trauma or injury to the scrotum. Ayurveda recommends shodhana treatment in this case. The procedure includes basti (medicated enema) and virechana (purgation) which help by reducing the fluid amount in the body thus preventing the accumulation of fluid.

For the management of the hydrocele Planet Ayurveda offers its medications that give very impressive results in this condition. The medications do not cause any side effects and are totally herbal.

Hydrocele Ayurvedic Treatment

The products offered are as following

  1.  Tribulus power
  2.  Kanchnaar guggul
  3.  Punarnava capsules 
  4. Water-ex tablets

Products Description

1. Tribulus power

Gokshur (Tribulus terrestris) works as a natural diuretic and eliminates toxins. It helps in generating energy and improves blood circulation in the scrotum and helps in the absorption of fluid present in the hydrocele sac and thus prevents testicular atrophy.

Dosage – 2 capsules twice daily with plain water after meals.

2. Kanchnaar guggul

This is a classical herbal formulation which can play a very important role in managing the swelling in the testis. Kanchnaar guggul has

  • kanchnaar bark (Bauhinia variegata)
  • amalaki (Emblica officinalis)
  • bibhitaki (Terminalia bellerica)
  • haritaki (Terminalia chebula) and many more

Dosage – Two tablets twice a day after meals.

3. Punarnava capsules

Punarnava (Boerhavia diffusa) is the only constituent of these capsules. These capsules help in removing excessive water content from the body and also help in the absorption of serous fluid present in the hydrocele sac.

Dosage: One capsule twice a day after meals.

4. Water-ex tablets

The formulation contains three herbs that are the best known diuretics. These herbs are punarnava (Boerhavia diffusa), varuna (Crataeva nurvala) and gokshura(Tribulus terrestris). These herbs combinedly help in reducing water retention,balances vata and purifies blood.

Dosage – Two tablets twice a day after meals.

Contact my assistant to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214030 Or Check Website – www.PlanetAyurveda.com

Conclusion

Hydrocele is a situation that is usually seen in children and adults both. Such situations sare not to be ignored because prolonged accumulation of fluid can cause rupture of testis membrane, infertility, testis atrophy and many other conditions. The products offered by planet ayurveda in this case are totally herbal and do not cause any side effects. These products are made from the standardized extract of herbs and do not contain any adulteratives. In case of any query kindly visit www.planetayurveda.com