Category: Overweight (Obesity)

Herbal Treatment of Glycogen Storage Disorder

What is glycogen?

Glycogen is the primary carbohydrate stored in the liver and muscle cells of animals. Glucose is stored inside the cells in the form of glycogen. The sugar needed for the body to provide energy for daily metabolic activities are provided by the glucose. And this glucose is converted into glycogen and also glycogen is catabolized back into glucose as per the times of requirement. There are a number of enzymes that accompany the process too.

So the process of converting glycogen back to glucose at times of immediate energy requirement to maintain the blood glucose levels is called glycogenolysis and the process of forming glycogen from glucose is called glycogenesis. Takes place when the blood glucose levels are sufficient or to allow the storage of excess glucose in liver and muscle cells.

What are glycogen storage disorders?

Glycogen storage disorders are formed due to the malfunctioning of a protein or enzymes (enzymes are made of proteins) responsible for glycogenolysis or gluconeogenesis. The enzyme disorders are the main reason why there will be an inadequate amount of glycogen produced in the body or the resultant effect like abnormal glycogen production.

If the enzymes linked with the glycogenolysis are affected it will lead to a low or excess levels of glucose in blood too. Resulting in conditions like hypoglycaemia (low levels of glucose in the body).

Different types of glycogen storage disorders.

Depending on which enzyme is lacking or functioning abnormally, there are mostly 12 types of glycogen storage disorders. The disorders likely affect the cells of the liver and muscles. It also tends to affect the kidney, heart, blood vessels, bowels, and the neural system also gradually. The important ten types being as follows,

  • Von Gierke’s disease (type I : most common)
  • Pompe’s disease (type II)
  • Forbes-cori disease (type III)
  • Andersen’s disease (type IV)
  • Mc ardle’s disease (type V)
  • Hers disease (type VI)
  • Tarui’s disease (type VII)
  • Liver phosphorylase kinase deficiency (type IX)
  • Fanconic- Bickel syndrome (type XI)
  • Lewis disease (type 0)

Glycogen Storage Disorder

How do you get glycogen disorders and what are the symptoms?

Mostly the glycogen disorders are inherited. Passed on through families via genes. The symptoms depend on the type of disorder.

  • Type I, IV, VI, IX affects the liver.
  • Type V, VII affects muscles.
  • Type III affects both muscles and liver.

The common systems will include

In children

  • Slow growth along with weak muscles.
  • Low blood sugar levels leading to sweating, tremor, confusion, uncontrolled muscle movements and convulsions, drowsiness etc.
  • Enlarged liver which doctors inspect on child’s tummy.
  • Obesity and kidney problems
  •  Bleeding disorders and clotting issues.

In case of teenagers and adults it can lead to fatigue and exhaustion even at the slightest of physical activities. Muscles can be weak and might even ace. Few disorders depending upon their underlying reasons can affect your immune system making you susceptible to infections.

Diagnosis and Treatment

Blood tests, biopsy and scanning are most adopted medical techniques to diagnose glycogen storage disorders. For treatment we need to stabilize that disarray in the glycogen and glucose levels of blood. Diet plan will help a lot. In Ayurveda a healthy diet and necessary physical activities corresponding to the health issues will heal your body to a greater extent. So stick to a diet plan. High protein content if given as an input and the use of nutritional supplements like glucose can be helpful.

Now the tricky cases appear as well, when the patients stop responding to nutritional supplements. In those instances we may occasionally go for liver transplant. For immunity to decrease, a regular antibiotic protection for the body to cope up against infection may also be adopted. Replacement therapy for enzymes are also administered now to reverse the condition ensuring their optimal functioning in metabolic reaction

So if you are searching for nutritional supplements, here are some of our best choices from Planet Ayurveda. Planet ayurveda is a trusted and famed organisation offering products across all over the world. The experts of planet ayurveda suggests some of the formulations for the management of these  disorders which are as follows :-

  1. Kumar kalyan ras
  2. Energo Plan syrup
  3. Arogyavardhini vati
  4. Nourish Maxx
  5. Ashwagandha Capsules
  6. Chanderprabha vati

Herbal Remedies for Glycogen Storage Disorder

Glycogen Storage Disorder

 

Products Description

1. Kumar kalyan ras

It is a herbal mineral known to treat paediatric and heat related ailments with the help of their herbal formulations. The ingredients being kumari rasa (Aloe Vera juice extract), sheedha shuddha parada (purified mercury), abhraka basma (purified and processed mica) and a lot more ingredients blessed with therapeutic value. The herbal formulation is known for their ability to bring about the vitiated or decreased levels of pitta dosha back to their normalcy. It is to be consumed as 1 daily in chewable form.

Dosage- 1 tablet once  a day with plain water after meals

2. Energo Plan syrup

With the magical combination of herbs including amalaki (Emblica officinalis), ashwagandha (withania somnifera), gokshura (tribulus terrestris) and pippali (piper longum) this syrup restores your energy level and maintain the active endurance power within the body. Planet ayurveda’s energoplan syrup could be consumed daily by all family members. Its formulations will protect the body from harmful toxins and pillars the natural immune responses of the body.

Dosage- 2 tsp twice daily after meal

3. Arogyavardhini vati

This is an ayurvedic medicine in capsular form produced by planet Ayurveda to help fight against fever, skin and liver diseases. The formulations ate tridosha pacifiers making the body’s optimal balance on vata, pita and kapha doshas within an endurable limit. It acts as an active digestive stimulant and improves bio-fire thereby keeping endotoxins in the body. The ingredients like haritaki (chebulic myrobalan fruit),amalaki (indian gooseberry), tranda and neem juice extracts help the same purpose.

Dosage– 2 tablets twice  a day with plain water after meals

4. Chanderprabha vati

The 120 capsules tablets are more than enough for your nutritional requirements on a daily basis. It improves the overall functioning of the body. It brings back the disrupted kapha dosha levels back to normalcy as well as assists in the maintenance of optimal levels of vata. The ingredients like curuma longa (haridra), amala, guduchi(tinospora cordifolia) and pippali (piper  nigrum) are known to weaken insulin resistance by 88% and enhance glucose uptake by the cells. Their weak anti-infective properties also come handy in conditions like glycogen storage disorders.

Dosage– 2 tablets twice  a day with plain water after meals

5. Nourish Maxx

This is the pure vegan formula for nourishing the whole body. This can be your best choice of natural supplement to be coupled with a low fat diet and an active lifestyle. Prepared out of the herbal combinations containing shatavari (Asparagus racemosus), safed musli (Chlorophytum borivilianum), ashwagandha (Withania somnifera)  and gokshura (Tribulus terrestris). It is the plant based protein powder for better muscle strength to be consumed either in powder form or by boiling in water. This helps to improve tissue nutrition thereby providing strong and healthy movements and an effective motor activity system in the body.

Dosage- 1 tsp twice daily with plain water after meals

6. Ashwagandha Capsules

This is a renowned rejuvenative herb in Ayurveda widely used as an adaptogen for coping up with physiological as well as psychological stress. Ashwagandha pacifies Vata and Kapha because of its hot potency and unctuous nature. It is best known for supporting optimal anabolic reactions in the body. The same which we have incorporated in our capsules.

Dosage– 2 capsules twice daily with plain water after meals

Contact my assistant to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214030 Or Check Website – www.PlanetAyurveda.com

At last , we can conclude that the above-mentioned herbal formulations are very good and effective in managing Glycogen storage disorders.These formulations are  free from any kind of preservative, chemical, additive and preservative and do not produce any adverse effects. For more queries you can consult online through herbalremedies123@yahoo.com.

Treatment of Dvt/ Varicose Vein (Sira Vikar) in Ayurveda

Abstract

The venous system in our body is a huge branching network of structures that carry deoxygenated blood away from the systemic tissues to the heart. It would not be wrong to say that beneath the layer of visible skin we have a huge spread meshwork of Veins, venules, capillaries, arterioles, arteries etc. Ayurveda has considered a total of 700 Sira (Veins) in the human body. Its massive expansion in the body is beautifully compared to the venation pattern of the leaves. Ayurveda believes the common origin of all the veins is Nabhi (the naval). It is from this point that the veins diverge in the upper (urdhva), lower (adho) and the diagonal (tiryak) directions.The vein being functional for an entire-time until the person lives, are vulnerable to the obvious wear, tear, and also the complicated pathologies. Ayurvedic correlation of the same can be made to Sira Granthi.  This article discusses a very common venous pathology “Varicose vein”. This is a complete pathology in itself and is also a mere etiology for complicated conditions such as DVT. This article discusses the cause, pattern,sign-symptoms, pathology and management of this disease.

Introduction

Varicosity of the vein pertains to dilation, elongation and torsion of the vein. It is found commonly in the “superficial venous system of long or short saphenous”,  “esophageal varix”, “hemorrhoidal veins”,”spermatic veins” etc.

Varicose vein

The venous drainage in undertaken via

  1. Deep Veins
  2. Superficial Veins
  3. Perforating or connecting veins

1. Deep veins

Anatomically these veins are located in the close proximity to arteries.These have a better build-up of veins in them which directs the flow of blood upwards and prevents its regurgitation due to gravity. Examples of such kinds of veins are- Peroneal vein,popliteal vein,tibial vein,femoral veins etc.

2. Superficial Veins

These veins lie between the skin and the deep fascia. It is found where the subcutaneous fat is seen. Examples of subcutaneous veins are Long (begins in the medial marginal vein of foot and ends in the femoral vein) and Short (begins in the lateral marginal vein of foot and ends in the popliteal vein) Saphenous veins.

Perforating or communicating Veins

These veins join deep veins to superficial veins.These veins have a good build-up of valves that prevent the backflow of blood from superficial veins to the deep veins. It is due to the failure of these valves that the blood retrogates back to the superficial veins and causes “Varicose veins”.

Etiology

There are many factors that are causative to varicose veins and they are

  1. Prolonged standing– When a person occupationally or habitually stands for really longer durations,his blood in the lower limbs pressures ( due to gravity) against the valves.This dysfunctions valves and brings the retrograde flow of blood.
  2. Obesity– Adiposity or the fat accumulation offers poor support to the veins.
  3. Gereatric Degeneration– In old age the vein walls experience atrophications which makes them incompetent.
  4. Athletes– Due to over activity the veins get exerted pressures by the contractions of calf muscles which forces blood in reverse direction through perforating veins. This brings destruction to the Valves and causes “Varicose veins”.
  5. Pregnancy-The pregnant state is accompanied with the release of progesterone hormone which brings dilatation and relaxation of the veins of the lower limb (most common in the first trimester of pregnancy). The pregnant uterus also puts more pressure over inferior vena cava which becomes a reason of obstruction in the normal flow.

Types

There are three different types of Varicosities

  1. Primary varicose veins– This type is mainly a result of valve failure. For example a pathology in a saphenofemoral valve causes varicosity in long saphenous veins.
  2. Secondary varicose veins– This type of various vein is due to some obstructions such as physical growths (tumours, fibroids,cysts), DVT, progesterone (in multiparous), arteriovenous fistula etc.
  3. Congenital varicose veins– This type is majorly seen among the children less than 20 years of age.The reason may be arteriovenous fistula ,haemangioma etc.

Clinical Features

Below are the clinical features of DVT

  1. Fatigued aching legs
  2. Severe pain while walking
  3. Tortuous and dilated veins
  4. Swollen ankles
  5. Pigmented skin associated with itching

Investigations

Following investigations should be done to rule out DVT

  1. Venography ( X ray of veins after an injection of a dye)
  2. Doppler Ultrasound(to measure the amount of blood flow)
  3. Photoplethysmography( to see volumetric changes of the blood )
  4. Duplex ultrasound  (an imaging of blood flow and the vessels)
  5. Local examination tests like Brodie Trendelenburg test,Tourniquet test,Perth’s test,Cough impulse test,Fegan’s method test etc.

Complications

If the disease is not treated in the first place that can cause severe complications in the later stages of life.  It might cause “Thrombophlebitis”, “Pigmentation”, “Eczema”, “Venous ulcer”, “ Hemorrhage”

Treatment

  1. Palliative managementThe use of long stockings all day long (not in the night) and practising the exercises such as cycling of feet while lying down on the back.
  2. Operative treatment-Several operative procedures such as Ligation (of long saphenous vein), Ligation with stripping,Sclerotherapy or Fegan’s injection therapy,Radiofrequency ablation ,Endovenous laser surgery etc are performed.

Deep Vein Thrombosis

If the pathology like varicose veins is not treated properly then it might result in the severe complications such as “Deep Vein Thrombosis”or Phlebothrombosis. The predisposing factors of DVT are stasis, increased blood coagulability, and injury to the vascular wall. Varicose veins and several other causative factors such as minor injuries, visceral cancer, surgery, diabetes, pregnancy, infection, obesity, use of contraceptive pills are contributory to hypercoagulation of the blood thereby leading to the condition of “ Venous thrombosis”. Venous thrombosis may be superficial or deep. Buerger’s disease and visceral cancer can cause visible Trousseau’s sign of superficial venous thrombosis.

Deep Vein Thrombosis or Phlebothrombosis is a condition in which the thrombus is loosely attached to the vein wall from which the emboli displaces causing fatal pulmonary embolism.

Clinical Features of Dvt

  1. This condition may be asymptomatic for the majority of the patients.
  2. A severe aching pain at the site of thrombus can be felt. This usually aggravates standing.
  3. Minimal inflammation too can be seen.

Physical Findings

  1. Physically swelling, tenderness is visible
  2. Homan’s sign is positive- In this test on dorsiflexion of the foot, the calf veins that are thrombosed, pains.
  3. Mose’s sign is positive- In this test the calf muscle on being squeezed, pains.
  4. Lab investigations such as Phlebography, plethysmography, Doppler ultrasound and Duplex ultrasound can confirm DVT findings.

Management of Dvt

Prevention

  1. Venous intimal injury and hypercoagulability must be avoided in any form.
  2. Leg must be elevated above the level of heart.
  3. Exercises like plantar flexion can be beneficial considerably.
  4. Elastic stockings must be worn.
  5. Bed rest is advised ( it prevents thrombus emboli from spreading)
  6. Sitting and standing idly should be avoided.

Medications

  1. Anticoagulants such as heparin ( should not however be discontinued abruptly)
  2. Coumarin derivatives such as warfarin
  3. Fibrinolytic drugs such as streptokinase ( converts plasminogen into plasmin)

Surgery

  1. The affected vein is by- passed if possible.
  2. The vein if larger (such as vena cava, iliac vein) can be repaired via prosthetic material.
  3. Venous transplant
  4. Venous thrombectomy
  5. Insertion of umberally filter (this prevents pulmonary embolism)

Ayurvedic Understanding of Varicose Veins

The probable correlation of varicose vein can be made to the concept of Sira Granthi in Ayurveda. Ayurveda considered the vitiated Vata dosha the main culprit behind this pathology. Vitiated vata increases the pressure over valves and hence dysfunctions them. It also distorts the elasticity of veins.

Ayurvedic Management

Ayurveda manages this pathology by balancing the vitiated Vata doshas. It makes use of Vatrakt chikitsa, abhyanga(massage),dhara,Sira vyadha and leech therapy.There are several herbs provided by our mother nature that can be very beneficial (due to their ras,gun,virya,vipak) against these diseases.

Herbs for varicose veinTreatment of varicose vein

Herbal Remedies for Varicose Veins

Planet Ayurveda has made use of ancient wisdom and has come up with very effective results against fibroids. Planet ayurveda is a globally emerging herbal manufacturing hub that formulates herbomineral /herbal formulation that are obtained from 100% natural sources with strict adherence to ayurvedic texts and principles .These herbal medications are being made under strict vigilance and guidance of expert ayurvedic physician using ancient time tested formula.

Planet Ayurveda offers a Varicose Vein care pack which includes the following

  1. Gotu kola Capsules
  2. Curcumin Capsules
  3. Triphala Guggul

Products Description

1. Gotu kola Capsules

This formulation is made up of pure standardized extract of Mandookparni (Centella asiatica) which supports healthy blood circulation. The effective action of balancing the vitiated tridoshas in the pathology behind varicose vein brings enormous relief. This drug also balances the psychic energies and alleviates the stress (which is a major causative  factor behind the further compilation such as DVT)

Dose- 1 Capsule twice a day

2. Curcumin Capsules

This formulation has standardized extract of Curcuma longa which works amazingly over inflammations, pathogenic infestations, pain etc that could be associated along with varicose vein or the thrombotic embolisms.

Dose-1 Capsule twice a day

3. Triphala Guggul

This formulation has

  • Emblica officinalis (Amla)
  • Terminalia billerica ( Bibhitaki),
  • Terminalia chebula ( Haritaki)
  • Piper longa(Pippali)
  • Purified Commifora mukul( Guggul) in it.

This formulation boosts metabolism,flushes toxins out of the body and pacifies the inflammation.

Dose– 2 Tablets twice a day

Conclusion

This pathology is very severe but unfortunately goes unnoticed for the majority of the time. Nowadays stress has become an inevitable part of everyone’s life, and this stress is the major hypercoagulability factor. Stress should be reduced to minimal levels and then accordingly its management should be advised.