Category: Ulcerative Colitis

April 5, 2024

Mesacol Side Effects & Safe Alternative Treatment for IBD (Crohn’s Disease & Ulcerative Colitis) in Ayurveda

ABSTRACT

The intestinal illness known as ulcerative colitis is treated using an anti-inflammatory medication called Mesacol Tablet. By lessening intestinal inflammation, it aids in the reduction of symptoms including diarrhoea, bleeding, and stomach discomfort. Mesacol is used in this autoimmune condition of IBD (Ulcerative colitis, Crohn’s disease). When the immune system unintentionally destroys healthy cells in the body, it results in autoimmune illnesses. Crohn’s disease, rheumatoid arthritis, and some thyroid disorders are among the types. Let’s discuss this in detail.

Inflammatory Bowel Disease

INTRODUCTION TO MESACOL

What Is Mesacol?

Mesacol contains mesalamine, a drug that belongs to the salicylates class of medicines. In patients with mild to moderate ulcerative colitis, a chronic inflammatory bowel disease, Mesacol tablets are used to treat and prevent the condition. It is also used to lessen the symptoms of ulcerative colitis, which often manifests in afflicted persons as diarrhoea, rectal bleeding, or stomach discomfort.

USES OF MESACOL

Mesacol helps to manage and avoid mild to severe ulcerative colitis, minimises ulcerative colitis symptoms, which often manifest in afflicted people as diarrhoea, rectal bleeding, or stomach discomfort.

BENEFITS OF MESACOL

  1. In Ulcerative Colitis

    2. The condition known as ulcerative colitis causes swelling and redness in the lining of the large intestine (colon) and rectum. Abdominal discomfort, regular diarrhoea, and bleeding may result from this.

  2. In Crohn’s Disease

    3. Crohn’s disease is an intestinal inflammatory condition that is chronic (long-lasting). The two most typical symptoms are diarrhoea and abdominal discomfort. Mesacol Tablet aids in symptom relief, inflammation reduction, and symptom prevention.

MODE OF ACTION OF MESACOL

For those who are afflicted with ulcerative colitis, Mesacol tablets relieve symptoms by inhibiting the synthesis of prostaglandins, which are chemical messengers that cause inflammation in the intestines. This reduces inflammation and ulceration.

COMMON SIDE EFFECTS OF MESACOL

  1. Pain in the stomach or epigastrium
  2. Flatulence
  3. Headache
  4. Vomiting
  5. Emesis
  6. Stomach ache
  7. Rash

UNCOMMON SIDE EFFECTS OF MESACOL

  1. Exhaustion, drowsiness, or vertigo
  2. Swelling and contusions
  3. Shaky or trembling, sore muscles
  4. Earache, throat pain, and hair loss
  5. Heartbeat in rapid motion
  6. Pancreatic inflammation accompanied by symptoms such as upper abdominal discomfort, nausea, or back pain
  7. Constipation or bleeding are indications of a non-cancerous growth in the back canal called a rectal polyp.
  8. Red, scaly welts with acne
  9. Face swollen

SOME RARE SIDE EFFECTS OF MESACOL

  1. Kidney Malfunction
  2. Highly susceptible to infection (because of a significant decrease in white blood cell counts)
  3. Photosensitivity (the term used to describe the skin’s enhanced sensitivity to UV and solar rays)

SAFE ALTERNATIVE TREATMENT FOR MANAGING IBD (UC AND CROHN’S DISEASE) IN AYURVEDA

In Ayurveda, it is correlated with Raktatisaar and Khasataj Atisaar. Ayurvedic philosophy states that an imbalanced dosha can lead to a stoppage of prana, the life energy, which can result in waste accumulation and digestive problems. Pitta Pradhana Ulcerative colitis is thought to be caused by vata doshas, an imbalance between pitta and vata in which vata is heightened by strong and bitter flavours.

  1. Kutaj (Holarrhena antidysenterica) : It is agni deepak (appetising), pachak (digestive), grahi (absorbent) in nature.
  2. Lodhra (Symplocos racemosa) : It is grahi (absorbent), Sheetal (cold), and rakta stambhak (helpful in bleeding disorders).
  3. Durva (Cynodon dactylon) : It is Sheetal (cold), Raktskandan (blood coagulation) in nature.
  4. Ushir (Vetiveria zizanioides) : It is Sheetal (cold), stambhak (restraining) in nature.
  5. Nagarmotha (Cyperus rotundus) : It is deepan (appetising), pachan (digestive), grahi (absorbent) in nature.
  6. Arjuna (Arjuna terminalia) : It is sheet (cold), and raktsangrahik (helpful in bleeding disorders) in nature.
  7. Naagkeshar (Mesua ferrea) : It is sangrahi (absorbent), rakt sangrahak (helpful in bleeding disorders), and Aam Pachak (purifies toxins) in nature.
  8. Bael (Aegle marmelos) : It is helpful in grahi (absorbent) and deepan (appetising) in nature.
  9. Lajwanti (Mimosa pudica) : It is sangrahi (absorbent) in nature.
  10. Annar (Punica granatum) : It is grahi (absorbent), rochak, raktashodhak (blood purifier), and Sheetal (cold) in nature.

ALTERNATIVES OF MESACOL BY PLANET AYURVEDA

The greatest herbal products are produced by Planet Ayurveda, an herbal pharmaceutical firm. The business has GMP certification. Planet Ayurveda offers genuine, natural goods. The items don’t have any additional pollutants or impurities. The results of Planet Ayurveda’s products are what make them most well-known. The following goods are a few of the top substitutes for Mesacol.

  1. Kutajghan vati
  2. Vatsakadi churna
  3. Pitta Balance
  4. Arjuna capsules

Ulcerative Colitis Care Pack

PRODUCTS DESCRIPTION

1. Kutajghan Vati

Kutajghan vati is the formulation of Planet Ayurveda which consists of only a single herb, Kutaj (Halorhena antidysentrica). Kutaj is an effective herbal remedy in case of diarrhea and dysentery. Due to astringent and absorbent properties, it improves gut functions hence beneficial in IBS and ulcerative colitis. It reduces intestinal motility thus, tackles diarrhea and dysentery. It has the potency to improve digestive fire and is an effective medicine in case of blood disorders, and hemorrhoids.

DOSAGE : 2 tablets twice daily after meals with plain water.

2. Vatsakadi Churna

Vatsakadi churna is the preparation of Planet Ayurveda which consists of many herbs like kutaj (Halorhena antidysentrica), Bilva (Aegle marmelos), Saunf (Foeniculum vulgare), and some others also. It is an effective herbal powder for IBS and gastritis. It is useful in Crohn’s Disease, ulcerative colitis, and abdominal discomfort.

DOSAGE : 1 teaspoon twice daily after meals with plain or lukewarm water.

3. Pitta Balance

Pitta Balance is the preparation of Planet Ayurveda which consists of Praval pishti (coral compound), Akik pishti (Agate compound), and some others. These capsules balance the fire element in the body, unusual heat feeling in the body, burning feet and hands, aggression, anxiety, and anger management.

DOSAGE : One capsule twice daily after meals with plain water.

4. Arjuna Capsules

Arjuna Capsules are prepared by Planet Ayurveda and consist of only a single herb that is Arjuna (Terminalia arjuna). It is an anti-allergic and anti-inflammatory medicine that helps in preventing infection. It is very effective in the treatment of piles, ulcers, and diarrhoea. It improves the metabolism of the body and helps the body to recover from all digestive problems.

DOSAGE : 2 capsules twice daily after meals with plain water.

CONCLUSION

When the immune system of the body unintentionally targets and kills healthy bodily tissue, it might result in an autoimmune illness. An anti-inflammatory drug called Mesacol Suppository is used to treat ulcerative colitis, a kind of colon illness. It is used when proctitis, or inflammation of the inner rectum’s lining tissue, occurs. By lowering intestinal inflammation, it helps to lessen symptoms including diarrhoea, bleeding, and stomach discomfort. There are many alternatives of mesacol in Ayurveda that help in the treatment of IBD (Ulcerative colitis and Crohn’s disease). This article includes all the main points and information regarding the best alternatives and treatments for IBD in Ayurveda.

Contact Planet Ayurveda Support Team to provide you the costing/ordering and delivery information at costing.planetayurveda@gmail.com or Call at 0172-521-4040 (India), +91-172-521-4040 (Outside India) or Whatsapp at (+91) 842-749-4030.

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October 6, 2023

Herbal Remedies for SAVI – String-Associated Vasculopathy Infancy Dependent

ABSTRACT

It is a rare autoinflammatory disease. SAVI causes severe lung disease and interstitial lung disease. It occurs due to mutations in the STING1 gene which gives the instruction for making STING (stimulator of interferon genes) protein. It involves the abnormal inflammation in the body that is in the skin, lungs, and blood vessels. Inflammation normally occurs when the white blood cells of our body reach the site of injury to fight against bacteria and help in tissue repair. Excessive inflammation damages the tissues and cells of our body. Inflammation occurs due to autoinflammatory disease.

INTRODUCTION

SAVI is an inflammation of the body due to a mutation in the STING1 gene in the body. It starts from the first few months of life. The signs and symptoms are mostly of blood vessels and damage to tissue. As an infant suffers from SAVI the lesions occur on the face, nose, and ears. These lesions start in the form of lesions and turn into ulcers and lastly tissue damage. The skin problems mostly worsen in cold weather. Due to abnormal blood vessels in the skin, the skin turns into purplish discoloration. People affected with SAVI also experience symptoms of Raynaud phenomenon as fingers and toes turn white or blue in colour due to exposure to cold temperatures and any type of stress.

autoinflammatory disease

PATHOPHYSIOLOGY

When the protein content STING shifts to its normal position the SAVI disease occurs. Normally, the STING protein is present in the cytoplasm of cells but in this condition, the protein is present in the Golgi apparatus.

CAUSES

The main cause of SAVI is mutation in STING1 genes. There are some risk factors that cause SAVI are described below-

  1. A positive family history
  2. Abnormality in the cytoplasm of cells

SYMPTOMS

The SAVI includes the following symptoms

  1. Interstitial lung disease
  2. Skin lesions on fingers, cheeks, nose, toes and soles
  3. Myositis (when the immune system attacks the muscles of the body)
  4. Joint stiffness
  5. Rashes on skin
  6. Blisters on skin
  7. Ulcer in the mucous membrane
  8. Ulcers on the skin
  9. Abdominal pain
  10.  Difficulty in breathing
  11.  Swelling and inflammation in hands and feet
  12.  Vomiting
  13.  Diarrhea
  14.  Fever
  15.  Anemia
  16.  Fatigue

DIAGNOSIS

The SAVI include the following diagnosis

  1. Clinical examination
  2. Evaluation of medical history
  3. Assess the signs and symptoms of patients
  4. Blood test- ESR (erythrocyte sedimentation rate) and C-reactive protein are elevated
  5. Skin biopsy- Shows the inflammation of capillaries
  6. Lung biopsy- Shows the follicular hyperplasia and fibrosing alveolitis

COMPLICATION

The SAVI includes the following complications

  1. Chronic inflammation
  2. Scarring of skin
  3. Disfigurement of skin
  4. Loss of mobility
  5. Organ damage mostly involves the lung
  6. Gangrene forms on the tips of the finger

TREATMENT

The treatment includes the following

  1. Control the inflammation
  2. Prevent organ damage
  3. Supportive care is given to reduce symptoms
  4. Steroids – To reduce inflammation
  5. Antibiotics -To prevent infections
  6. Immunosuppressant – To suppress the immune system

AYURVEDA ASPECT FOR STRING-ASSOCIATED VASCULOPATHY INFANCY DEPENDANT

  • As  Acharya Charak explained in Sharira sthana च.शा.०३ chapter खुडाक गर्भावकृान्ति शारीर (Khuddika Garbhavkranti Sharira ) explained बीज दुष्टि (defect in ovum and sperm).
  • The defect in the ovum and sperm is due to 3 reasons: बीज (sperm and ova), बीज भाग (chromosomes), and बीज भाग अवयव (genes). In च.शा.०४।०४ the 7 भाव (qualities) are described by Acharya Charak that is  मातृज भाव (maternal factor), पितृज भाव (paternal factor), आत्मज भाव (soul),   सात्मयज भाव (wholesomeness), रसज भाव (nutritional factor), and सत्वज भाव (psych/mind). The disorder is found before the birth so considered in  सहज रोग.
  • As the dosha is vitiated the signs and symptoms are seen according to the severity of the disease.

HERBAL REMEDIES FOR STRING-ASSOCIATED VASCULOPATHY INFANCY DEPENDANT BY PLANET AYURVEDA

Planet Ayurveda is GMP-certified. Their products are 100% pure, easy to use and free from any type of adulterant, preservatives, fillers, yeast, and chemicals. The products are prepared under the guidance of an M.D. Ayurveda experts. The products are effective and have no side effects. The herbal remedies by planet Ayurveda for string-associated vasculopathy infancy dependant-

Product list

  1. Boswellia curcumin
  2. Arvindasav
  3. Syrup Infee
  4. Manjishtha capsules

Product Description

1. Boswellia curcumin

The Boswellia capsules contain Curcumin (Curcuma longa), and Shallaki (Boswellia serrata). Inflammation in blood vessels and lungs is associated with SAVI so curcumin helps to reduce inflammation as it has anti-inflammatory properties. Curcumin also reduces muscle weakness, and muscle pain and protects from muscle damage. As skin discoloration and ulcers form on the skin, the shallaki helps to reduce those symptoms.

Dosage– 1 capsule twice daily, with plain water, after meals

2. Arvindasav

The Arvindasav has a mixture of many herbs as it contains Bach (Acorus calamus), Kachoor (Curcuma zedoaria), Amla (Embilica officinalis), Sarva (Hemidesmus indicus), Sarfonka (Tephrosia), water and many more herbs. As a mental weakness, jatamansi helps to improve mental weakness. As skin discoloration is there amla improves skin complexion. As Arjuna has antioxidant properties it prevents the formation of free radicals that cause skin damage. Munakka has anti-microbial and anti-inflammatory properties; it reduces bacterial infections and also reduces inflammation.

Dosage– 2 teaspoons daily after meals

3. Syrup Infee

The syrup contains extract of Yashtimadhu (Glycyrrhiza glabra) and Guduchi (Tinospora cordifolia). Yashtimadhu helps to improve the degeneration process, and skin-related problems, and reduces weakness or fatigue of the body. Guduchi has the property of immunomodulator which helps to improve the immune system of the body.

Dosage– 2 teaspoons twice daily with water

4.  Manjishtha capsules

The capsules are made up of a single extraction of Manjistha (Rubia cordifolia).Skin discoloration associated with SAVI Manjistha helps the skin for its natural color, it also reduces the ulcers and blisters present on the skin.  Manjistha contains madhura, tikta, and kshaya rasa so pacifying the pitta dosha and helpful in reducing fever. It contains astringent properties so reduces mobility and is helpful to treat diarrhoea. It promotes skin glow in both ways, internally and externally.

Dosage– 1 capsule twice daily, with plain water, after meals.

Contact Planet Ayurveda Support Team to provide you the costing/ordering and delivery information at – costing.planetayurveda@gmail.com or Call at 0172-521-4040 (India), +91-172-521-4040 (Outside India) or Whatsapp at (+91) 842-749-4030.

CONCLUSION

In this article, we talk about the introduction, causes, symptoms, diagnosis, and treatment of string-associated vasculopathy infancy dependent. As the doshas are imbalanced there is an imbalance in the functioning of the body. In Ayurveda च.शा.०३ chapter खुडाक गर्भावकृान्ति शारीर tell about the बीज दुष्टि. Where defect in ovum and sperm at the time of fusion of gametes. There are three main reasons for this defect in the ovum and sperm, genes, and chromosomes. As this disease is hereditary it is considered in सहज रोग. The planet Ayurveda provides herbal remedies to treat the string associated with vasculopathy infancy dependent Boswellia curcumin, Arvindasav, Syrup Infee, and Manjishtha capsules.

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