Category: Child Health

June 19, 2023

What Are Antioxidants and How They Are Helpful in Improving Health?

Antioxidants

ABSTRACT

Wonder why health experts focus on a good diet and fruit consumption. That’s because they are rich in antioxidants and nutrients. Consumption of fruits and vegetables rich in antioxidants plays a pivotal role in health. They contain antioxidants that help us to get good health. Radiance of skin, the capability to resist the pollution that causes damage to our bodies, protection of our body from wear and tear, and prevention from various health ailments are all because of antioxidants. There are a wide range of antioxidants.

They can be natural or manmade. All offer good health to you.

Antioxidants

INTRODUCTION

Antioxidants are substances that inhibit the damage caused by the oxidation process(oxidative stress) in the cells. During the oxidation process, free radicals are produced in our bodies which are called reactive oxygen species(ROS). Free radicals are unpaired electrons that are unstable and very reactive. They gain stability after binding with other electrons. So, these free radicals bind with various proteins, lipids, and DNA to alter the working of organs and cause diseases. Antioxidants are produced either inside our body (cell metabolism), or outside our body (pollution, radiation,). In order to prevent ourselves from free radicals we need to eat food that is rich in antioxidants. Astaxanthin, Anthocyanins, phenolic acids, flavonoids, lignans, carotenoids (xanthophylls and carotenes), and vitamins like vitamin E and vitamin C are rich in antioxidants. How do we know which food has more antioxidants? ORAC (Oxygen Radical Absorption Capacity) is a measure that calculates the amount of antioxidants in the food. Indian gooseberry, sorghum, ginger, and coffee are some foods that are higher in antioxidants. Foods rich in antioxidants slow down the oxidative process and radical damage. So now we know the importance of fruits, vegetables, and supplements. We eat antioxidants that protect us from diseases and are very important for our health.

HEALTH BENEFITS OF ANTIOXIDANTS

REJUVENATING FUNCTION

Antioxidant consumption slows the ageing process. It rejuvenates the body cells and enhances the turnover of epidermal skin.

ANTI-INFLAMMATORY FUNCTION

Free radicals are responsible for inflammation in the body. During inflammatory response, Leukocytes and mast cells act on the region of damage thereby producing more free radicals in damage and releasing ROS. Antioxidants act by scavenging free radicals and reducing ROS hence decreasing inflammation.

ANTI-CANCEROUS FUNCTION

Antioxidants like glutathione are responsible for decreasing distribution caused by cancerous free radicals.

BRAIN HEALTH

Neurological disorders like schizophrenia, dementia, and Parkinson’s disease are prevented by the optimum use of antioxidants by inhibiting the activity of free radicals. Astaxanthin is known to cross the blood-brain barrier and is useful in brain-related disorders.

GOOD IMMUNITY

Antioxidants like vitamins A, C, E, and beta carotenes increase susceptibility to fight against infection.

FOOD SOURCES OF ANTIOXIDANTS

  1. Dry fruits (Walnuts, pistachios, almonds, hazelnuts, chilgoza, etc).
  2. Berries (Gooseberries, blackberries, crane berries, etc)
  3. Spices(Turmeric, cloves, cumin, cinnamon, etc)
  4. Herbs(Tulsi, Kesar, Giloy, aloe vera, rosemary, mint, etc)
  5. Fruits(Apples, dates, kiwis, grapes, coconut, oranges, tomatoes, peaches, pomegranates, etc)
  6. Vegetables(broccoli, spinach, carrots, pumpkin, asparagus, artichokes, beetroot, garlic, onion, radish, etc)
  7. Pulses(green grams, soya beans, chickpeas, green peas, etc)
  8. Grains (Rakta shali ie. Red rice, Mahashali ie. Basmati rice, Yava ie. Barley)
  9. OILS: Sunflower oil, primrose oil, almond oil, jojoba oil, mustard oil, etc.

ANTIOXIDANT DEFICIENCY

Antioxidant deficiency occurs when we consume foods that are not rich in antioxidants or our daily recommended antioxidant uptake is not met by the food we eat. Antioxidant deficiency leads to oxidative stress causing damage in our bodies leading to diseases like recurrent cough, cold, infections, heart disease, atherosclerosis, arthritis, Parkinson, senile dementia, and cancer.

HERBAL REMEDIES FOR STAYING HEALTHY THROUGH ANTIOXIDANTS BY PLANET AYURVEDA

Planet Ayurveda provides the best combination of effective herbal remedies as an Antioxidants Pack for good health. It is a polyherbal pack that contains Cranberry capsules, Spirulina capsules, Amalaki rasayan, Immune booster, Brahmi chyawanprash, etc. For natural and herbal treatment always look for natural products which contain pure extracts and are formulated under GMP guidelines. Planet Ayurveda products are scientific and certified. They are free from any chemicals, additives, and preservatives. Planet Ayurveda products are formulated by MD Doctors and are 100% natural, pure, and free from side effects.

Product List

  1. Cranberry Capsules
  2. Spirulina Capsules
  3. Amalaki Rasayan
  4. Immune Booster
  5. Brahmi Chyawanprash

Herbal Remedies for Staying Healthy Through AntioxidantsHerbal Remedies for Staying Healthy Through Antioxidants

PRODUCT DESCRIPTION

1. Cranberry Capsules

Cranberry capsule is an ayurvedic formulation that contains a single ingredient that is cranberry (vaccinium oxy-coccus). Cranberries contain antioxidants that prevent a number of diseases. Cranberries are rich in a number of antioxidants like flavonoids, anthocyanins, polyphenols, vitamin C, E, and K. According to Ayurveda cranberries have vitta-balancing properties and it is helpful in slowing the process of ageing. It is Ushna (hot) and Snigdha (oily) in nature. Cranberry is also useful in the prevention of urine infections.

Dosage: 1-2 capsules twice daily.

2. Spirulina capsules

Spirulina capsules contain extract of spirulina (Spirulina platensis). It is a Blue algae (Cyanobacteria) rich in antioxidants. It is rich in protein, Vitamin B1, B2, B3, B6, B9, Vitamin C, Vitamin A, and E. Spirulina has the highest ORAC value (24000).

Dosage: 1-2 capsules daily twice with plain water after meals.

3. Amalaki rasayan

Amalaki rasayan is a herbal formulation that contains Amalaki (Emblica officinalis) in its purest form. Amalaki is rejuvenating in nature. It is rich in vitamin C and other antioxidants. It contains all 5 rasas (sweet, sour, bitter, astringent) except lavan rasa(salt). It is Madhura (sweet) in vipaka (post digestion effect) and shita (cold) in virya (potent energy).

Dosage: 1-2 capsules twice daily with plain water after meals.

4. Immune booster

Immune booster is a wonderful formulation that contains grape seed (Vitis vinifera), Go-Piyush (Bovine colostrums), Bhumi Amla (Phyllanthus niruri), Amalaki (Emblica officinalis). It contains grape seeds that are rich in antioxidants like linoleic acid, vitamin E, zinc, etc and Go-Piyush is the first milk produced after the birth of a calf. It contains proteins, antioxidants, and antibodies to fight against immune system-related disorders. In ayurveda, according to Yogratnakar milk has 10 properties that are similar to that of ojas (immunity). It is a Rasayana (rejuvenator), jeevaniya (enlivening), Medhya (improves intelligence), balya (improves immunity) in nature.

Dosage: 1-2 capsules daily twice with plain water after meals.

5. Brahmi Chyawanprash

Brahmi chyawanprash is an effective herbal formulation. It contains Brahmi (Bacopa monnieri), Dashmoola (Roots of 10 herbs), Bala (Sida cordifolia), Ashwagandha (Withania somnifera), Bhumi amla (Phyllanthus niruri), Shatavari (Asparagus racemosus), Nagarmoola (Cyperus rotundus), and many other ayurvedic herbs. It contains Brahmi which has antioxidant properties and is responsible for enhancing memory and concentration. It is used to manage vitiated vata dosha. Acharya Chakradutta has written that Brahmi is beneficial in all types of epilepsy. It helps in aiding the prevention of neurodegenerative diseases. Brahmi chyawanprash is useful in reducing oxidative stress produced by free radicals.

Dosage: 1-2 teaspoons, twice to thrice daily after meals, preferably with milk.

Contact Planet Ayurveda Support Team to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or Call at 0172-521-4030 (India), +91-172-521-4030 (Outside India) or Whatsapp at (+91) 9915-593-604

CONCLUSION

In order to reduce oxidative stress and damage caused by unstable free radicals. Nature has provided us with antioxidants that are present in the food we eat which are helpful in providing immunity and reducing the severity of diseases. Antioxidant consumption is of major concern in infections and diseases like cancer, neurodegenerative diseases. The deficiency of antioxidants can be fulfilled by either consuming foods which are higher in ORAC values or by taking herbal supplements. Therefore, we can conclude that antioxidants play a major role in promoting good health.

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June 12, 2023

Sting Associated Vasculopathy of Infancy (Savi)- Treatment in Ayurveda

ABSTRACT

SAVI is a disorder or vasculopathy which begins during the infant period. It is a very rare inflammatory disease when there is inflammation throughout the body especially in skin, blood vessels and lungs. It manifests as systemic inflammation, interstitial lung disease and cutaneous infection. Patients present with recurrent cough, failure to thrive, skin scaling, poly arthritis, interstitial lung disease, and necrosis and auto amputation. SAVI is type1 interferon disorder caused due to mutations in STING1 stimulator of interferon gene protein. Patients carry heterogeneous substitutions in STING1. It is a life threatening condition because there is a gain of function mutations in STING1. Sting regulates various pathways such as functioning of proteins. Lung involvement leads to morbidity and mortality in sting associated vasculopathy. Chest CT and lung biopsy are the measures to diagnose this disorder during infancy. As it is a genetic disorder there is risk of another child being born with a similar problem. In this article we will discuss STING associated with vasculopathy of infancy, its cause, symptoms, diagnosis and its treatment according to classical Ayurveda texts.

SAVI-String Associated Vasculopathy Infancy

INTRODUCTION

SAVI is a genetic disorder which begins in neonates or infants causing systemic illness and vasculopathy of small vessels. Due to excessive inflammation in the body it leads to destruction of the body’s own cells and tissues. It is also known as auto inflammatory disease. Most patients have problems with blood vessels and tissues which affects blood circulation. There is particular damage to skin tissues of the face, nose, toes, fingers, etc. Skin lesions appear which develop into wounds. Skin problems may worsen during cold weather and cause skin discoloration. Sometimes it may involve the respiratory system which can be a life threatening condition (affects breathing pattern). The patient may have intermittent low grade fever and may affect lymph nodes. There is quite a therapeutic limitation of sting associated vasculopathy of infancy as supportive treatment can be done. The severity of disease depends on the number of gene mutations taking place. There is association of interferon genes protein characterized by skin and lung symptoms. There is over activation of type1 interferon pathway. STING is a transmembrane protein which plays an essential role to innate immunity against viral and bacterial pathogens.

CAUSES

As we know SAVI is a genetic disorder which onset during infancy and there is disturbance in one or more genes. It can be inherited disorder like autosomal dominant inheritance. There is a mutation in the STING1 gene. This gene helps in functioning of proteins and immune system responses. In this disorder beta interferons are produced which is a kind of protein that promotes inflammation. This inflammatory change leads to tissue damage and leads to development of signs and symptoms.

SYMPTOMS

The sign and symptom of this disease starts appearing during infancy. By growing age, symptoms may differ and they appear at any age. Some of symptoms of SAVI are as following

  • Skin lesions
  • Ulcers, necrosis (non- healing)
  • Skin discoloration ( purplish)
  • Low grade fever
  • Swollen lymph nodes
  • Finger/toe tips white or bluish
  • Interstitial lung disease
  • Pulmonary fibrosis
  • Difficulty in breathing
  • Joint stiffness
  • Muscle inflammation
  • Cardiovascular involvement
  • Esophageal reflux
  • Tachypnea
  • Anemic syndrome

DIAGNOSIS

The diagnosis for SAVI are as following

  • Clinical examination
  • Medical history
  • In Ayurveda darshan, prashan and sparshan is done. (inspection, history and examination)
  • CBC (Hb- decreased, ESR- raised)
  • Antenatal and postnatal examination
  • Genetic metabolic screening/ sequencing
  • Imaging like chest x- ray
  • Biopsy
  • Gene testing
  • Duplication analysis

MANAGEMENT

As we know it is a genetic disorder, no specific treatment is available. SAVI is a very challenging condition for managing so supportive treatment is done. Some of the measures are given as following

  • Corticosteroids
  • Immunosuppressant
  • Biologic agents
  • Somatic gene therapy

AYURVEDIC POINT OF VIEW REGARDING STING ASSOCIATED VASCULOPATHY IN INFANCY (SAVI)

Ayurveda is a traditional system of medicine which believes in natural herbs (aushadh), lifestyle activities (vihar) and dietary changes (aahar). In classics there is no particular correlation with sting associated vasculopathy of infancy but according to symptoms it can be related according to dosha predominance such as there is predominance of vata and kapha dosha. According to Acharya kashyap in vednaadhya (chapter related to different kinds of disorders in children) it can be related to its signs and symptoms. So, as Ayurveda believes in dosh, dhatu and mala this disease can be treated accordingly.

HERBAL REMEDIES FOR STING ASSOCIATED VASCULOPATHY OF INFANCY BY PLANET AYURVEDA

Planet Ayurveda is a well authorized and GMP, ISO certified manufacturing company. It has been spread throughout the world due to its purity in natural and herbal products. All the formulations prepared here are as discussed in our classical texts and under expert supervision. Products manufactured here are free from any preservative, color, starch, yeast, etc. The best combination of herbal medicines for Sting Associated Vasculopathy of Infancy (SAVI) by Planet Ayurveda are as following

Product List

  1. Boswellia Curcumin
  2. Arvindasav
  3. Syrup Infee
  4. Manjishtha Capsules

PRODUCT DESCRIPTION

1. Boswellia curcumin

It is a standardized capsule formulation prepared from the extract of shallaki (Boswellia serrata), haldi (Curcuma longa). These capsules have anti-inflammatory properties and reduce all types of pain. It has antioxidant properties and cures degenerative disorders. It plays an important role in the respiratory system such as in asthma.

Dosage- One capsule twice daily with plain water after meals.

2. Arvindasav

It is a syrup formulation from our ancient classical texts prepared from extract of kamal phool (Nelumbium speciosum), khus (Vetiveria zizanioides), gambhari (Gmelina arborea), etc. It promotes proper growth and development of children. It increases appetite, digestion and corrects recurrent respiratory infections. It corrects delayed milestones and rickets problems in infants. This syrup improves appetite, strength in children.

Dosage- Two tablespoons mixed with equal amounts of water taken twice daily after meals.

3. Syrup Infee

This is a syrup formulation prepared from extract of yastimadhu (Glycyrrhiza glabra), guduchi (Tinospora cordifolia), bibhitaki (Terminalia Billerica), etc. It acts as an immunomodulator and protects children from repeated infections. It boosts child immunity and helps ingrowth of the child. It protects children from recurrent respiratory and GI infections. It helps to strengthen weak children and children suffering from cough and bronchitis.

Dosage- Two tablespoons twice daily with plain water after meals.

4. Manjishtha capsules

It is standardized capsule formulation prepared from extract of manjishtha (Rubia cordifolia). It acts as a blood purifier, anti platelet, anti stress and calcium channel blocker. It is used to treat skin problems (skin rejuvenating, lightens if any spots) and has anticancer properties.

Dosage- One capsule twice daily with plain water after meals.

Contact Planet Ayurveda Support Team to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or Call at 0172-521-4030 (India), +91-172-521-4030 (Outside India) or Whatsapp at (+91) 9915-593-604

Conclusion

Sting associated vasculopathy is a very rare, genetic auto inflammatory disease which begins during the infant period. This disorder can affect a child’s life as it involves tissue damage of skin, vessels and pulmonary system. Here Planet Ayurveda gives the best combination of medicines for SAVI as they are prepared under expert’s supervision. For any severity you may concern the physician and team of planet Ayurveda is always there for any type of guidance.

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