Category: Child Health

ABSTRACT

The osteogenesis imperfecta is also known as Brittle bone disease. It is a genetic disorder that breaks the bones easily. With the help of amniocentesis, osteogenesis imperfecta can be determined before birth. It is a lifelong condition as a child born with soft bones that break easily and lead to fractures of the bone. It has 8 types and signs and symptoms seen according to the severity of the disease. It is genetic as inherited from parents, due to deformity in one or two genes as genes help in forming the collagen. As collagen is present in connective tissue and connects or supports the whole body.

INTRODUCTION

It presents at birth the bones will become very soft and break easily. Signs and symptoms will vary according to the severity of the disease. As it is a genetic disorder it passes through genes so it may be inherited from the mother or father. On the basis of signs and symptoms and inheritance osteogenesis imperfecta has 8 types. Type 1 is the mildest and most common form as it has minor deformities and half of patients have the type 1 form. Type 2 is a severe form as children die within a week of birth due to a soft skull, short arms, and legs, a small chest, low birth weight, lungs not fully developed, and born with fractured bones. Type 3 is the most severe type as the baby does not die and remains alive as a result at the time of birth the baby has shorter arms and legs than the normal child and a large head with triangle shaped face, deformity in the spine, and chest, and difficulty in breathing and swallowing. Type 4 is diagnosed at the time of birth as the symptoms are from mild to severe, the arms and legs of the baby are not straight, and not grow normally. Type 5 symptoms are medium to severe as they occur in enlarged thickened areas where large bones are fractured. Type 6 is very rare and symptoms are medium and similar to type 4. Type 7s have shorter arms, thighbones, and height than the normal ones. Type 8 has very soft bones and severe growth problems.

CAUSES

The causes of osteogenesis imperfecta are-

1. Genetic
2. Abnormality in collagen

SYMPTOMS

The osteogenesis imperfecta shows the following symptoms-

1. Bones break easily
2. Muscle weakness
3. Discoloration of the sclera (white part of the eye)
4. Soft teeth
5. Discoloured teeth
6. Hearing loss
7. Loose joints
8. Joint hypermobility
9. Short stature
10. Curved spine
11. Barrel shape chest (when lungs are overfilled with air and cannot deflate usually)
12. A triangle shape face (when the face shape is broader at the jawline and narrower at the forehead)
13. Breathing problems
14. Dentinogenesis imperfecta (Problem with teeth)

DIAGNOSIS

The following investigations are done to check Osteogenesis imperfecta:-

1. Check the symptoms of the patient
2. Collagen biopsy to determine the structure and quantity of collagen
3. X-ray- To show deformed bones and fractures
4. DEXA (Dual-energy X-Ray absorptiometry) Scan – To find out the softening of bones
5. DNA sequencing
6. Urine test
7. Blood test

TREATMENT

1. Prevent deformities of bones
2. Prevent fractures
3. Care of fractures
4. Orthopedics treatment
5. Bisphosphonate medicines
6. Rodding to prevent deformities of long bones
7. Assistive devices such as a wheelchair may be needed as the baby grows

AYURVEDA ASPECT FOR OSTEOGENESIS IMPERFECTA  

In Ayurveda, Acharya mentioned in च.सू.१७।६७ अस्थिक्षय (decrease in bone tissue) and मज्जाक्षय (decrease in bone marrow). As the dosha is in an imbalanced state there is vridhi and kshaya of dosha. Due to an imbalance in vata dosha, there is asthi kshaya. As acharya charak explained different types of kshaya in our body, which one is asthi kshaya. Vata vyadhi is mainly occurring due to 2 reasons धातुक्षयजन्य (decrease in the amount of dhatu), and  स्त्रोतोअवरोधजन्य (obstruction in channels).

अस्थिक्षय in च.सू.१७।६७-

“केश लोम नख व्दिज पृपतनं श्रम ज्ञेयमस्थिक्षय रूपं सन्धिशैथिल्यमेव च ”

1. Falling of hair, nails, hairs of beard
2. Weakness
3. Looseness of joints

मज्जाधातुक्षय in च.सू.१७।६८

“शीयन्ते इव चास्थीनि दुर्बलानि लघूनि च पृततं वातरोगाश्च क्षीणे मज्जानि देहिनाम”

1. Degeneration in bones
2. Weakness and lightness in bones
3. Decrease in vata dosha

HERBAL REMEDIES BY PLANET AYURVEDA FOR OSTEOGENESIS IMPERFECTA

Planet Ayurveda is GMP-certified. The products are made under the guidance of m.d. Ayurveda experts. The products are made up of natural herbs that are 100% pure and easy to use without any side effects, and free from any type of adulterants, chemicals, yeast, fillers, or preservatives. The Planet Ayurveda offers herbal remedies for osteogenesis imperfecta are-

Product list-

1. Lakshadi Guggul
2. Bone support
3. Cissus power capsules
4. Boswellia curcumin
5. Gandhak rasayan
6. Arjun ghrit

PRODUCT DESCRIPTION FOR OSTEOGENESIS IMPERFECTA

1. Lakshadi Guggul

The Lakshadi Guggul tablets are made up of natural herbs as they contain Arjuna (Terminalia arjuna), Asthisamharaka (Cissus quadrangularis), Ashwagandha (Withania somnifera), and many more herbs. Laksha is a good source of calcium so it is given for a fast healing process, joint pain, low bone density, and bone fracture. As Arjuna has bone regeneration properties it helps in improving bone formation, maintaining bone density, strengthening the bones, and also improving the healing of bone fractures. Ashwagandha helps in bone calcification so it increases the bone cell’s production, and reduces inflammation for better healing of bones.

Dosage– 2 tablets twice daily with lukewarm water

2. Bone support

The bone support capsules contain Suhanjana Beej (Moringa oleifera), Shudh Laksha (Laccifer lacca), Arjun (Terminalia Arjuna), and many more herbs. Arjun helps in maintaining bone density which helps in improving bone formation and provides strength to bones. Mukta provides strength to bones, muscles, and joints and also has anti-inflammatory properties which help in the absorption of calcium which improves bone density and strengthens the bones and connective tissue helping in preventing breakage of bones. It also improves the collagen amount which protects the bones from damage.

Dosage– 1 capsule twice daily with plain water, after meals

3. Cissus power capsules

The cissus powder capsules are made up of the stem extraction of Cissus quadrangularis (Hadjod). Hadjod is rich in vitamin C, increases cells, and helps in the absorption of calcium which helps in the formation and mineralization of bones. It also increases bone density and bone strength. Reduces pain and inflammation helpful in reducing joint pain. It prevents the loss of bone tissue. It promotes cell growth and regeneration.

Dosage– 1 capsule twice daily, with plain water, after meals

4. Boswellia curcumin

The Boswellia curcumin capsules are made up of Curcuma longa (Curcumin), and Boswellia serrata (Shallaki). Shallaki is a natural herb to treat bone disease as it contains anti-inflammatory properties It reduces pain, and swelling of the joints, and prevents excessive tear and wear of joints. It is also a natural analgesic so helps to reduce pain in joints. Curcumin helps in the build and repair of the bone. It also inhibits osteoclastic bone resorption.

Dosage– 1 capsule twice daily, after meals with plain water

5. Gandhak rasayan

The gandhak rasayan tablets are made up of a single standardised extraction of Shuddha Gandhak (Sulphur). It is used to treat weak bones and fractured bones. Sulphur helps to make collagen and glucosamine which are helpful in healthy joints and bones. It produces immunoglobulin which makes the immune system healthy. It has anti-inflammatory properties so protects the cartilage from damage as a result less pain in joints and improves movements of joints. It contains hydrogen sulphide that helps in bone formation.

Dosage– 2 tablets twice daily

6. Arjun Ghrit

The arjuna ghrit is a classical formulation that contains Amalaki (Emblica officinalis), Bahera (Terminalia bellirica), Haridra (Curcuma longa), Nagarmotha (Cyperus rotundus), Nimbu (Citrus limon), ghee and more herbs. As Arjuna has a bone regeneration process it helps to make healthy bones and joints. It regulates calcium and phosphorus metabolism in the body so helps with the bone formation process. It improves bone density, provides strength to bones, and heals bone fractures. It prevents joint movements and reduces the chance of degeneration of bones.

Dosage– half teaspoon twice with warm milk or water.

Contact my assistant to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214040

CONCLUSION

As we studied in this article the introduction, causes, symptoms, and herbal remedies by Planet Ayurveda. In Ayurveda, Acharya mentioned in च.सू.१७ the

अस्थिक्षय and मज्जाक्षय means a decrease in bone tissue and bone marrow. As vata dosha predominates in this condition as vata dosha and asthi kshaya oppose one another as one increases another one decreases. Vata vyadhi mainly occurs due to a decrease in the amount of dhatu and obstruction in channels. Planet Ayurveda provides herbal remedies to cure osteogenesis imperfecta which are 100% pure and without any side effects. The remedies are Lakshadi Guggul, Bone support, Cissus power capsules, Boswellia curcumin, Gandhak rasayan, and Arjun Ghrit.