Category: Low Immunity

Ayurvedic Treatment for Hemophagocytic Lymphohistiocytosis (HLH) In Adults

Abstract

Hemophagocytic lymphohistiocytosis is a rare disease that usually occurs in infants and adults. Most babies have this problem. Many things can cause Hemophagocytic lymphohistiocytosis in adults, including cancer and disease. In this disease, your immune system is affected and does not work properly. Some white blood cells, primarily lymphocytes and histiocytes, attack other cells in the blood, including abnormal cells that build up in the liver and spleen and cause large tumours. Therefore, in this article today, we will briefly understand hemophagocytic lymphohistiocytosis.

Hemophagocytic Lymphohistiocytosis (HLH) in Adults

Introduction

Adult hemophagocytic lymphohistiocytosis is a life-threatening or rare disease in immunocompromised adults. It is usually a secondary reaction to an underlying disease, such as immunosuppression or another disease or malignancy, and requires immediate treatment for effectiveness. It is also called hemophagocytosis or hemophagocytic syndrome. This severe condition is caused by the uncontrolled growth of active macrophages and lymphocytes that secrete high levels of cytokines.

Causes

The cause of hemophagocytic lymphohistiocytosis can be inherited or acquired. Causes are:-

  1. Weak immune system
  2. Viral infection, mainly the Epstein-Barr virus
  3. Cancer
  4. Fungal infection
  5. Bacterial infection
  6. Metabolic disorders

Types of Hemophagocytic Lymphohistiocytosis

Hemophagocytic lymphohistiocytosis are of two types:

1. Primary Hemophagocytic lymphohistiocytosis

It is a genetic condition that occurs after a mutation. In this, symptoms usually appear within the first few years of life and this can happen if you are born with a genetic predisposition to primary Hemophagocytic lymphohistiocytosis. These symptoms rarely occur in adulthood.

2. Secondary Hemophagocytic lymphohistiocytosis

Secondary Hemophagocytic lymphohistiocytosis occurs when you have an underlying condition that affects the functioning of your immune system. Other conditions that can cause Hemophagocytic lymphohistiocytosis include infection, cancer, or autoimmune disease. Secondary Hemophagocytic lymphohistiocytosis is more common than primary Hemophagocytic lymphohistiocytosis.

Symptoms

  1. Fever
  2. Rashes
  3. Thrombocytopenia
  4. Loss of consciousness
  5. Seizures
  6. Anaemia
  7. HepatomegalyPale skin
  8. Dizziness
  9. Irritability
  10. Headaches
  11. Weakness
  12. Jaundice
  13. Difficulty breathing
  14. Enlarged lymph nodes
  15. Retinal haemorrhages
  16. Splenomegaly
  17. Coma

Diagnosis

  1. Complete blood count: to detect the level of red blood cells, white blood cells, and platelets.
  2. Liver function test
  3. Blood tests: to detect any infection in the blood
  4. Bone marrow biopsy: to examine the blood cells of the bone marrow
  5. Genetic test

Treatment

  1. Antibiotics
  2. Immunosuppressants
  3. Blood transfusion
  4. Allogeneic stem cell transplant
  5. Gamma-blocking antibody

Ayurvedic Aspect

In Ayurveda, we can associate this disease with tridoshas-vata, pitta, and kapha. All three doshas are connected with each other. When kapha is broken down, it accumulates in the tissues of the body and increases pitta dosha. Kapha and pitta affect vata channels, causing inflammation or pain in the tissues, and excess kapha causes inflammation in various organs of the body. All the doshas go in the wrong direction, causing disorders in different parts or organs of the body.

Some Herbal Remedies for Hemophagocytic Lymphohistiocytosis by Planet Ayurveda

Planet Ayurveda is a GMP-certified Ayurvedic clinic that formulates various medicines to prevent various health problems and provide relief to sick people. All preparations that are formulated by Planet Ayurveda do not contain any preservatives, additives, or resins. These remedies are 100% pure, are formulated under the strict guidance of Ayurvedic MD practitioners, and do not cause any side effects. For the treatment of Hemophagocytic lymphohistiocytosis in adults, Planet Ayurveda provides many herbal supplements for this disease that do not cause any side effects.

Product List

  1. Kanchnaar Guggul
  2. Boswellia Curcumin
  3. Immune Booster
  4. Giloy Ghan Vati
  5. Liv Support
  6. Gandhak Rasayan
  7. Telomere Boostup

Herbal Remedies for Hemophagocytic Lymphohistiocytosis Buy Now: Herbal Products for Hemophagocytic Lymphohistiocytosis

Product Description

1. Kanchnaar Guggul

Kanchnaar Guggul is a multi-herbal formulation that is made by Planet Ayurveda using various ingredients: Bauhinia variegata (Kachnar Bark), Emblica officinalis (Amalaki), Cinnamomum tamala (Tejapatra), Terminalia chebula (Haritaki), Terminalia bellerica (Bibhitaki), Crataeva religiosa (Varuna Bark), and many more. This formulation is dry, light, and hot in potency. It helps in the reduction of vitiated kapha and rakta dhatu. It has antiviral, antibacterial and anti-inflammatory properties. It helps to improve the menstrual cycle in women.
Dosage: with lukewarm water, take 2 tablets twice daily.

2. BOSWELLIA CURCUMIN

Boswellia curcumin is a polyherbal formulation that is formulated by Planet Ayurveda using Curcuma longa (Haridra) and Boswellia serrata (Shallaki). It is dry, light, and hot in effect and pungent and bitter in taste. It has antioxidant properties that protect the brain and its functions. It has anti-inflammatory properties that help in stopping the secretion of cytokines and reduce swelling or inflammation. It is helpful in autoimmune diseases and also effective in cancer or tumours.
Dosage: with plain water, after meals, take 2 capsules twice daily.

3. Immune Booster

Immune booster is a multi-herbal formulation that is formulated by Planet Ayurveda with the help of Vitis vinifera (Grape seed), Bovine colostrum (Go-Piyushs), Phyllanthus niruri (Bhumi amla), and Emblica officinalis (Amalaki). Bhumi amla is beneficial for liver disease because it normalises the bilirubin level. It is also beneficial for bacterial and viral infections. It also helps with skin conditions and kidney-related diseases.

Dosage: with plain water, after meals, take 1 capsule twice daily.

4. Giloy Ghan Vati

Giloy Ghanvati is a single herbal formulation that is formulated by Planet Ayurveda with the help of Emblica officinalis (Giloy). It is heavy, unctuous, and cold in effect and bitter and astringent in taste. It acts as an immunomodulator, a rejuvenator, an antioxidant, and a restorative tonic. It also acts as a stomachic, a blood purifier, a nutritive, and a bitter tonic. It is beneficial for skin diseases.

Dosage: with lukewarm water, take 2 tablets twice daily.

5. Liv Support

Liv support is a multi-herbal formulation that is formulated by Planet Ayurveda with the help of Kalmegh (Andrographis paniculata), Bhringraj (Eclipta alba), Saral (Pinus roxburghii), and Kasani (Cichorium intybus). It is pungent and bitter in taste and dry, light, and hot in effect. It aggravates pitta and pacifies vata and kapha. It is beneficial for the liver. It contains diuretic, digestive, and laxative properties.

Dosage: with plain water, after meals, take 1 capsule twice daily.

6. Gandhak Rasayan

Gandhak rasayan is a single herbal formulation that is formulated by Planet Ayurveda with the help of Shuddha Gandhak (Purified sulphur). It is antibacterial, antimicrobial, antipyretic, anti-inflammatory, anti-allergic, and antiviral. It is helpful for urinary tract infections. It is a good blood purifier and kills intestinal worms. It contains various antioxidants, acts as an immunity booster, and is indicated for infertility, indigestion, debility, breathlessness, and abdominal pain.

Dosage: with lukewarm water, take 2 tablets twice daily.

7. Telomere Boostup

Telomere bosstup is a multi-herbal formulation that is formulated by Planet Ayurveda with the help of Withania somnifera (Ashwagandha), Vitis vinifera (Grapeseed), Emblica officinalis (Amla), Commiphora wightii (Moringa), and Tinospora cordifolia (Giloy). Ashwagandha prevents all types of weakness, enhances strength and stamina, and improves general alertness. It contains analgesic, aphrodisiac, anti-inflammatory, and diuretic properties. It helps with digestion.

Dosage: with plain water, after meals, 2 capsules twice daily.

Contact Planet Ayurveda Support Team to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or Call at 0172-521-4040 (India), +91-172-521-4040 (Outside India) or Whatsapp at (+91) 9915-593-604

Conclusion

Hemophagocytic lymphohistiocytosis is a rare disease that usually occurs in infants and adults. Most babies have this problem. Many things can cause Hemophagocytic lymphohistiocytosis in adults, including cancer and disease. Adult hemophagocytic lymphohistiocytosis is a life-threatening or rare disease in immunocompromised adults. In Ayurveda, we can associate this disease with tridoshas-vata, pitta, and kapha. All three doshas are connected with each other. All the doshas go in the wrong direction, causing disorders in different parts or organs of the body. On Planet Ayurveda, there are some herbal remedies that are formulated by Ayurvedic experts for the treatment of Hemophagocytic lymphohistiocytosis, and these formulations give effective results.

Severe Combined Immunodeficiency (SCID)

Severe Combined Immunodeficiency (SCID)

Abstract

Primary immunodeficiency” means that it is a disease caused by the genetics of the immune system. Combined immunodeficiency syndromes are a group of different diseases caused by disturbances in the growth and function of T (Cellular immunity) and B (humoral immunity) cells, which may also include natural killer cells. When the immune system combination causes premature death (usually in the first year of life) from a serious infection, it is said to be “severe.” SCID can be arranged as typical SCID or on the other hand, assuming less serious, flawed SCID in light of the seriousness of cellular cell qualitative and quantitative lack. We will discuss pathogenesis, causes, symptoms, diagnosis, and treatment according to allopathy, Ayurvedic overview of SCID Oja doshas, ojahksaya, and Herbal remedies offered by Planet Ayurveda.

Severe Combined Immunodeficiency (SCID)

Introduction

It is an uncommon condition made by hereditary transformations that leads to modification in capability and improvement of immune cells. Babies with serious joined immunodeficiency look healthy at the hour of birth yet are very vulnerable to serious contaminations. This is a lethal condition until or except if babies get treatment for immune restoration like enzyme therapy and gene therapy.

Pathogenesis

SCID is a disease brought about by changes in a few qualities whose parts are significant for the turn of events and capability of T and B cells and can influence normal executioner cells. Now and again, sub-atomic deformities inactivate Immune system microorganisms, while B cells are significant. Despite this, Lymphocyte brokenness seriously obstructs compelling resistance since B cells need signals from Immune system microorganisms to create antibodies.

Causes

It is caused by

  • ADA (Adenosine deaminase) deficiency.
  • CD3 chains deficiency
  • Reticular dysgenesis
  • Omenn syndrome
  • Purine nucleoside phosphorylase deficiency
  • Bare lymphocyte syndrome
  • Genetic mutations
  • Janus Kinase 3 deficiency

Symptoms

Symptoms associated with SCID are as follows

  • weakness
  • lump
  • growth retardation
  • difficulty climbing
  • diarrhoea
  • pneumonia
  • respiratory disease
  • growth retardation
  • thrush
  • sinus infection
  • ear infection

Diagnosis

  • Newborn screening test
  • DNA test for genetic mutation
  • A full blood lymphocyte count

Treatment

  • Gene therapy
  • Chemotherapy
  • Bone marrow transplant

Prevention

You can diminish the gamble of disease in your child by taking the following preventive measures:

  • Staying away from public spots
  • Prevent the child from disease or cold
  • Restricting guests
  • Clean up appropriately before contacting the newborn child.

Ayurvedic Overview

In Ayurveda, we can associate this disease with anuvanshik vyadhi (genetic disease) and other ojahksaya (weak immune system). Anuvanshik vyadhi is formed at birth due to beej dosha (malformation of sperm and egg) deformity. Oja means to prevent disease or to prevent disease in two ways: one is to reduce the disease that occurs, and the other is to prevent the occurrence of the disease. The main factors that contribute to oja (immunity) are three principal doshas, balanced dhatu state, normal agni, the patency of srotas etc. It is what supports the state of all physiological parameters. Ojas is the essence of rasadhi dhatus, also known as Bala (strength).

Ojovaha Srotodusti Lakshana/ Trayo Ojodosha

त्रयो दोषा बलस्योक्ता व्यापद्वि स्रंसनक्षयाः । (सु.सू  १५ /३०)

There are three kinds of ojodosha.

  • Ojo Visramsa- Displacement from its natural place.
  • Ojo Vyapat- Ojas get vitiated by dosha and dusya.
  • Ojahksaya- Decrease in its quantity.

Hetu (Etiological Factors) of Oja Kshaya

अभिघातात् क्षयात् कोपाच्छोकाद्धयानाच्छ्र मात् क्षुधः

ओजः सड्.क्षीयते ह्योभ्यो धातु ग्रहणनिः सृतम्।

तेजः समीरितं तस्माद्विस्त्रंसयति देहिनः ।। (सु.सू  १५ /२८)

Trauma or injury, tissue depletion (dhatuksaya), anger, sadness, anxiety, fatigue, hunger, etc. For reasons Ojas decreases, causing dhatus to flow out and affect tejas, and provoked by Vata, causing many disturbances in the body.

Clinical Features of Ojahksaya

मूर्च्छा मांसक्षयो मोह: प्रलापोऽज्ञानमेव च ।

पूर्वोक्तानि च लिङ्गानी मरणं च बलक्षये ।। (सु.सू  १५ /३२)

  • Fainting
  • Depletion of muscles
  • Unconsciousness
  • Delirium
  • Improper perception of knowledge
  • Death

Prognosis of Oja and Bala Abnormalities

तत्र विस्त्रंसे व्यापन्ने च क्रियाविशेषैरविरुद्धैैर्बलमाप्याययेत् ।

इतरं तु मूढसंज्ञं  वर्जयेत् ।। (सु.सू  १५ /३३ )

Ojo visramsa and vyapat can be treated by taking drugs that are not different. Ojaksaya is an incurable disease as it is caused by improper understanding.

Planet Ayurveda Offers Herbal Remedies For SCID

Planet Ayurveda produces herbal products following ancient Ayurveda. All of our herbal remedies are made from natural herbs and age-tested formulas. We offer useful natural supplements for general health. Our herbal products are widely used in herbal medicine, herbal powder, herbal tea, herbal medicine, herbal oil, herbal juice, beauty and cosmetics etc. including various. In this disease, no specific treatment is available till now. Only supportive treatment will be given which can delay the progression of the disease and provide some immunity to fight against other infections. Planet Ayurveda provides herbal remedies for severe combined immunodeficiency which are the following

Products List

  1. Telomere Boostup
  2. Immune Booster
  3. Amalaki Rasayan
  4. Ashwagandha Capsule
  5. Shilajit Capsules
  6. Gandhak Rasayan

Herbal Remedies for Severe Combined ImmunodeficiencyAyurvedic treatment for Severe Combined Immunodeficiency

Product Description

1. Telomere Boostup

This polyherbal capsule is made up of Ashwagandha (Withania somnifera), Moringa (Commiphora wightii), Giloy (Tinospora cordifolia) etc. Its taste is bitter, sweet, and astringent. It is dry and hot in potency. It has a tonic effect on the brain and the nervous system. It acts as an anti-inflammatory, analgesic, diuretic and mildly sedative. It is an immune-modulator, antioxidant and hormone precursor which tends to regulate important physiological functions. It improves general alertness, prevents all types of weakness and increases strength and stamina. It also allays stubborn and recurring infections of the urinary tract. It keeps the heart healthy and prevents free radical damage. It induces sound sleep and reduces inflammation.

Dosage: 1 Capsule two times a day.

2. Immune Booster

This polyherbal capsule is made up of Bhumi amla (Phyllanthus niruri), Amalaki (Emblica officinalis) etc. Its taste is sweet and bitter. It is light and has a cold potency. It strengthens immunity and helps prevent daily wear and tear on the body. It is used to treat fever, anemia, and urinary and reproductive system problems. It also acts as a support for all physiological diseases of the body. It has hepatoprotective properties. So, it is used in the treatment of liver diseases. It contains antioxidants that destroy all bacteria in the body, remove toxins from the body and prevent diseases by reducing the amount of stomach acid. It is suitable for peptic ulcer, indigestion, cough, sore throat, vomiting, hyperacidity, anemia and many other diseases. It can also reduce the firmness of the skin and restore the urinary tract. It keeps the heart healthy and prevents free radical damage.

Dosage:  2 Capsules two times a day.

3. Amalaki Rasayan

It is a herbal medicine that is made up of Amalaki (Emblica officinalis). It has a cold potency. Its taste is sometimes sweet, bitter and pungent. It is dry and has a cold potency. It acts as an antipyretic, diuretic, antacid, and haemostatic. Suitable for nosebleeds, dysfunctional uterine bleeding, leukorrhea, menopausal syndrome, general weight loss, hair and eye problems, jaundice, oedema, cough and asthma. It also helps heal ulcers. It is a good antioxidant and supplement for many chronic diseases.

Dosage: 1 Capsule two times a day.

4. Ashwagandha Capsule

It is a herbal capsule that includes only one herb Ashwagandha (Withania somnifera). It has a hot potency and its taste is bitter and sweet. It helps increase muscle strength, enhances immunity, and supports good heart health. It is used as anti-stress medicine. It is useful in psychiatric disorders, lower backache, insomnia and in high blood pressure. It prevents weakness and improves general alertness as it is a good tonic for the brain. It helps increase body strength.

Dosage: 2 Capsules two times a day.

5. Shilajit Capsules

This single herbal capsule is made up of Shilajit (asphaltum). It has anti-inflammatory, antitumor activity, antioxidant, and anti-asthma properties. It improves digestive problems and improves memory. It regulates blood sugar in the body. It is good for kidney, heart and liver diseases. It increases haemoglobin in the body.

Dosage: 1 Capsule two times a day.

6. Gandhak Rasayan

This herbal tablet is made from Shuddha gandhak (purified sulphur). It is an anti-bacterial, anti-microbial, anti-allergic, antipyretic, anti-viral, broad-spectrum antibiotic. It kills intestinal bacteria and is a good blood purifier. It contains many antioxidants. It is an anti-inflammatory and is indicated for pregnancy, impotence, indigestion, shortness of breath and stomach pain. It detoxifies the blood, removes dirt and prevents secondary infections. It is very important in urinary tract infections as well as in removing harmful bacteria from the body.

Dosage:  2 Tablets two times a day.

Contact Planet Ayurveda Support Team to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or Call at 0172-521-4040 (India), +91-172-521-4040 (Outside India) or Whatsapp at (+91) 9915-593-604

Conclusion

Severe combined immunodeficiency virus is a rare disease characterized by genetic mutations that cause changes in the immune system and development. In Ayurveda, we can associate this disease with anuvanshik vyadhi (genetic disease) and another disease is oja kshaya (weak immune system). There is no specific treatment for this disease, but supportive care can slow the progression of the disease. For the best results, never miss your dose and follow your diet.