Category: Low Immunity

January 17, 2023

Ayurvedic Aspects of Granulomatous Meningoencephalitis (Gme)

ABstract

Granulomatous meningoencephalitis is an idiopathic inflammatory central nervous system of dogs. It commonly shows neuropathic changes in dogs and cats. The central nervous system includes the spinal cord and the brain which controls the essential functions of life which include the cerebrum and cerebellum. Specialized tissues known as meninges cover the brain and spinal cord and have cerebrospinal fluid. The peripheral nervous system has nerves which coordinate the rest of the body. Neurons connect with each other and form the neurological unit which has 2 units known as dendrites and axons. It can be due to infections or immune-mediated causes and contains three layers which are dura (outer layer), arachnoid (internal thin meninge) and Pia mater (thin and highly vascular membrane). In this article, we are going to discuss the causes, symptoms and ayurvedic aspects of granulomatous meningoencephalitis in detail.

INTRODUCTION

Granulomatous meningoencephalomyelitis is an inflammatory condition of the central nervous system which is mainly characterized by focal lesions which are present in the brain and spinal cord. It was first reported by Braund and his colleagues in 1978. Commonly seen in female dogs of young and middle age. The focal lesions are mainly seen in the white matter of the cerebrum, brainstem and in cerebellum. It commonly involves the infiltration by mononuclear cells which destroys the debris. In granulomatous inflammation, there are cuffs which are around the blood vessels of the brain and spinal cord. In pug dog encephalitis it is an idiopathic inflammatory disease which usually affects the prosencephalon which is commonly known as necrotising meningoencephalitis. It only differs from GME in more breakdown of the tissues and increase in eosinophils. The cells of the immune system release destructive biochemicals which invade the organisms of the disease’s tissue.

Granulomatous meningoencephalitis in Dogs

TYPES

1. Disseminated

It is the diffuse type of disease present throughout the Central nervous system. It is also known as inflammatory reticulosis. Accumulation of mononuclear cells and neutrophils around the blood vessels in the form of meningitis which causes fever and neck pain.

2. Focal

It is present as granuloma which sometimes mimics tumors found in the cerebellopontine angle. It is a chronic progressive disease (3-6 months).

3. Ocular

It is the uncommon form of Granulomatous meningoencephalitis which shows sudden blindness which is due to neuritis. This retinal detachment and secondary glaucoma are seen in this type.

PATHOLOGY

In granulomatous meningoencephalitis, it occurs mainly within the white matter of the CNS (Central nervous system) which is characterized by dense inflammatory cells which are arranged in whorling patterns. There are varying numbers of Lymphocytes, monocytes and multinucleated giant cells which are mainly seen in the cerebrum, cerebellum and in the cervical spinal cord. These perivascular cuffs merge at blood vessels to form the whorls which form nodules which is due to the MHC class 2 and CD3+ T cells hypersensitivity reaction. Granulomatous lesions get compressed and get invaded in CND parenchyma which results in necrosis and oedema. The lesions are seen in the brain stem especially the pontomedullary region and white part. This lesion is usually detected by CT and MRI techniques.

PUG DOG ENCEPHALITIS

A pug dog is a beautiful family dog which is associated with a rare neurological disease which is mainly fatal. Encephalitis is the inflammation of the brain tissue which tends to strike at 2-3 years of age. It causes inflammation and death of the brain tissue. Affects small dog breeds including Maltese, Chihuahuas and Yorkshire terriers. It is usually an auto-immune inherited disease, an idiopathic inflammatory disease which usually affects the prosencephalon (forebrain and thalamus). Also known as necrotising meningoencephalitis. The prevalence of pug dog encephalitis is about 1 % which differs from granulomatous meningoencephalitis which leads to breakdown and increase in the number of white blood cells (eosinophils).

SYMPTOMS

  1. Disseminated-
  2. Fever
  3. Pain in the neck region
  4. Loss of balance
  5. Depression
  6. Seizures

1. Focal

It usually affects the discrete bone area which resembles a tumor. Various symptoms include are

  • Blindness
  • Progressive weakness
  • Loss of balance
  • Dementia
  • Neurological signs

2. Ocular

It usually causes retinal detachment and glaucoma

  • Affects the nerves which are supplied to the eyes.

DIAGNOSIS

  1. Cerebrospinal fluid Analysis (CSF)
  2. Brain biopsy
  3. CT Scan (Computed tomography)
  4. MRI (Magnetic resonance imaging)

TREATMENT

  1. Corticosteroid with immunosuppressive drugs.
  2. Cytosine arabinoside
  3. Radiation therapy
  4. Procarbazine
  5. Cyclosporine
  6. Surgical removal of the brain Granulomatous meningoencephalitis (GME) lesion.

AYURVEDIC ASPECT

Ayurveda is the oldest system of holistic medicine which means Science (ved) of life. Ayurveda in veterinary medicine has mainly focused on animal welfare, treatment therapies and management. In Rigveda, physicians described the treatment for both animals and humans and Salihotra was the first credited as an animal healer and wrote a book on veterinary medicine. Pandavas (Nakul and Sahadev as experts treated animals and the ayurvedic treatment for animals in modern science is known as Pashu Chikitsa. Pashu Chikitsa has been a vital part of Indian history and many animals are considered vehicles of dogs and goddesses, which shows the importance of animals.

Granulomatous meningoencephalitis is a dog’s condition which affects the nervous system and in ayurveda, it generally relates to inflammation which is due to vitiated pitta doshas, the vitiation of Kapha doshas (shows numbness as the primary symptom) along with Vata doshas. However, it shows the vitiation of tridoshas and the treatment will be advised to balance the imbalance doshas which is seen in dogs. Animals too have three primary types of Prakriti (Vata, Pitta and Kapha). Ayurveda has a history of extensive veterinary treatment systems which makes sense to discover from ancient texts and bring out the natural and side-effect-free treatment for our pets. The various medications which are useful for the management of Granulomatous meningoencephalitis are-

  1. Dashmoolarishta
  2. Triphala Churna
  3. Giloy ghan vati
  4. Brahmi Ghrita
  5. Shankhpushpi Churna

HERBAL REMEDIES BY PLANET AYURVEDA FOR GRANULOMATOUS MENINGOENCEPHALITIS

Planet Ayurveda is an emerging US-FDA-registered, GMP-certified ISO 9001:2015 registered ayurvedic company which formulates its own medications as described in the ancient ayurvedic texts books. These formulations are prepared without any preservatives which cause any harmful effect on the human body. Products which are manufactured are pure and devoid of any kind of adulteration. For granulomatous meningoencephalitis in dogs, planet ayurveda provides many herbal formulations which are causing no side effects and are useful for dogs.

PRODUCTS LIST

  1. NEURO PLAN SYRUP
  2. BRAHMI CAPSULES
  3. ASHWAGANDHA CAPSULE
  4. VRIHAT VATCHINTAMANI RAS

herbal supplements for Granulomatous meningoencephalitis

Herbal Remedies for Granulomatous Meningoencephalitis

PRODUCTS DESCRIPTION

1. Neuro Plan Syrup

Neuroplan Syrup is a herbal syrup which is formulated by planet ayurveda using ingredients such as Brahmi (Bacopa monnieri), Bhojpatra (Betula utilis), Sonth (Zingiber officinale) and many more. Neuro plan syrup is helpful in maintaining pressure and stress on the nervous system. Enhances the power of nerves and strengthens memory and promotes energy. Has a soothing effect and relieves any kind of inflammation in the central nervous system.

Dosage- 10 ml teaspoon twice daily.

2. Brahmi Capsules

Brahmi Capsules are single herbal capsules made by planet ayurveda using a standardized extract of Brahmi (Bacopa monnieri). These capsules are working as rejuvenating for the nervous system, used in ancient times as a brain tonic so known as a memory enhancer. Brahmi Capsule is a good supplement for the liver and is helpful in detoxifying it and enhancing the period of life.

Dosage– 2 capsules twice daily after meal with plain water.

3. Ashwagandha Capsules

Ashwagandha Capsules are single herbal capsules from planet ayurveda which contain standardized ingredients such as Ashwagandha (Withania somnifera). These capsules increase stress resistance and improve memory-related performances and perform the normal functioning of the nervous system. Provides calmness and mental satisfaction. Provides proper nourishment to the brain for proper functioning.

Dosage– 1 capsule twice daily after meal with plain water.

4. Vrihat Vatchintamani Ras

Vrihat Vatchintamani Ras is a classical ayurvedic product which is prepared by planet ayurveda using Swaran Bhasma (Calx of gold), Mukta Bhasma (Calx of pearl), Loha Bhasma (Calx of iron) and many more. These tablets are helpful in treating imbalanced Vata dosha and pitta doshas. Rich in antioxidants which act as a nerve tonic and strengthen the muscles of the heart. Has a cooling effect which reduces the aggravated heat from the body.

Dosage– 1 tablet twice daily after meal with plain water.

Contact Planet Ayurveda to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214040 Or Check Website – www.PlanetAyurveda.com

CONCLUSION

Granulomatous meningoencephalitis is an idiopathic inflammatory central nervous system of dogs. It commonly shows neuropathic changes in dogs and cats. Commonly seen in female dogs of young and middle age. The focal lesions are mainly seen in the white matter of the cerebrum, brainstem and in cerebellum. And the ayurvedic treatment for animals in modern science is known as Pashu Chikitsa. Pashu Chikitsa has been a vital part of Indian history and many animals are considered vehicles of dogs and goddesses, which shows the importance of animals. For the treatment of granulomatous meningoencephalitis planet ayurveda provided many herbal products which are useful in this without causing any side effects.

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January 10, 2023

Monkeypox – Symptoms, Prevention and Ayurvedic Treatment

Abstract

Many human infections are caused by either bacteria or viruses, these are very common in all the most successful creatures on earth, their habitat is also changed according to the atmosphere like they are having different shapes and sizes on ice slopes and are different in deserts. Viruses are different from bacteria, they are even smaller than any micro-organism, this virus can only reproduce inside the body of the living host, and is very tough to win a battle with. Viral infections are the most serious communicable diseases that are known in medical science. A virus is a minuscule pocket of protein that contains genetic material and is much smaller than a bacterium. Viral infections can spread from one person to another by coughing, sneezing, vomiting, or getting exposure to infectious bodily fluids or from other physical activities. Monkeypox is also a viral disease that has the same family as smallpox. Usually these are not serious types. It causes rash and flu-type symptoms, this disease is caused by the Monkeypox virus which is a member of the orthodox virus genus and belongs to the family of Poxviridae. In this article, we are going to discuss the causes, symptoms prevention, and Ayurvedic treatment against the Monkeypox disease.

Introduction

Monkeypox is a rare disease in which a virus is transmitted to humans from animals, it is clinically less severe. The monkeypox virus was discovered in 1958, it was firstly found in lab-tested monkeys that were used for research, this disease is more common in central and West Africa. But in May 2022, researchers found this virus reporting outside of Africa now in July 2022, about three thousand cases of monkeypox which is found in the US. Monkeypox has spread across several countries and is a communicable disease. At first, this was a disease of animal hosting, including a range of rodents and non-human primates. Monkeypox virus is a double-stranded DNA virus that belongs to the Orthopoxvirus and to a family of Poxviridae.

symptoms of monkey pox virus

Mode of Transmission

Zoonotic Transmission Animal to Human transmission can result from close contact or direct contact with blood, bodily fluids, or cutaneous and mucosal lesions, by infected animals. Eating inadequately cooked meat products are made from infected animal’s flesh.

Human-to-human exposure results from close contact like direct contact with an infected person, transmitted through respiratory secretions, or face-to-face contact. Transmission can also occur via mother to the foetus due to the placenta or during childbirth or after birth because they are exposed when it is held.

Signs and Symptoms

The incubation time of the monkeypox virus is five to twenty-one days. This infection can be divided into two periods.

Invasion period – that starts from the zero-day and goes up to the fifth day, characterized by

  1. Fever
  2. Intense headache
  3. Lymphadenopathy (swollen lymph nodes) – these appear similar to smallpox, chicken pox, and measles.
  4. Pain in back
  5. Muscle aches
  6. Lack of energy (asthenia)

After a few days, a rash often develops, these start as painful flat red bumps, which further result in blisters filled with pus. Blisters crust over and fall off and in the last two to four weeks, this whole process can last two to four weeks. It can also be present in the mouth, vagina, and anus. Person-to-person it spreads from an infected person through close relations, it can spread from contaminated materials like clothing, bedding, etc.

In previous outbreaks, following symptoms usually seen like

  1. After your fever starts in one to three days, a rash appears and starts from the face then spreads to other parts of the body.
  2. Common on the hands, feet, arms, and legs in the following pattern like formation of macules, papules, and vesicles. Macules are just round lesions and papules are the raised bumps on the skin and when this structure starts to fill with pus then it is known as Pustules.
  3. People usually show these bumps formation in any part of the body.
  4. The infected person can spread the virus for up to 21 days. so try to protect the healthy persons near you with following measures that we are going to discuss in the above heading.

How Can We Prevent Monkeypox Virus?

The best way to help in prevention of monkeypox virus is –

  1. Avoid contact with infected animals that are having the chances of spreading their infection to one another.
  2. Avoid contact with infected materials that are used by an infected person.
  3. Cook all foods perfectly that consist of meat or other parts of the disease.
  4. Properly wash your hands, with disinfectant like soap and water.
  5. Use safety measures if you are coming into contact with the infected person.
  6. If a patient has touched the clean surface or where all are going to touch then thoroughly try to clean it with sanitizer.
  7. Personal protective equipment can also be used when you are in contact with an infected person.

Facts Regarding Monkeypox

  1. Monkeypox virus is a zoonotic virus that spreads from animals to healthy humans.
  2. WHO (World Health Organisation) has declared this disease a Public Health emergency of International concern.
  3. This disease was first discovered by 1958 and its first case was diagnosed in 1970 in the Democratic Republic of Congo.
  4. Monkeypox virus is the main cause behind the Monkeypox disease, this is a member of the orthopoxvirus genus in the family of Poxviridae.
  5. This disease can spread by direct contact between an infected person and a healthy person.
  6. This disease was first diagnosed in primarily tropical rainforest areas or central and West Africa and then spread to all other parts of the world.

Ayurvedic View

Ayurveda is a holistic science which helps to heal the body and neutralise all the doshas that are the main cause behind all the diseases that occur in the human body. Viral diseases and bacterial diseases are categorised under the Jeevanu roga that is a type of Agantuja roga. Jeevanu roga adds up various microorganisms that are developed in the external environment and enter into the human body. These are considered as the external factors that damage the body on a different basis.

These agantuka roga also shows symptoms like

Burning in the body (Daha), fever (jwara), itching (kandu), shoth (inflammation), etc.

These symptoms can be managed by being consulted by a general physician. Give proper history of having in contact with an infected person, infected animal or being exposed to the infected area. If you are already feeling these symptoms, then try to avoid contact with other healthy infected persons. Further medication has been prescribed below kindly have them if you are suffering from the monkeypox virus.

Herbal Remedies by Planet Ayurveda for Monkeypox virus

Planet Ayurveda is an holistic medicinal manufacturing company that is a GMP certified prepared by 100 percent natural products. These products that are manufactured here, are totally free from colours, dyes, fillers, chemical compounds and various other harmful compositions. These products are made by classical methods that are written in Samhitas and in classical textbooks and made under the supervision of most experienced MD Ayurveda experts. Some of the effective formulations that are used to manage the Monkeypox virus disease.

  1. GANDHAK RASAYAN
  2. CURCUMIN CAPSULES
  3. SEPTRIN TABLETS
  4. MAHA SUDARSHAN KWATH

Herbal Remedies for Monkey Pox Virus

herbal remedies for monkey pox virus

PRODUCTS DESCRIPTION

1. CURCUMIN CAPSULES

This single herbal formulation manufactured by Planet Ayurveda consisting of haridra (Curcuma longa), this is a medicinal preparation that is used to kill the various microorganisms that are not good for our body. Curcumin has various health properties like it is anti-inflammatory, anti-oxidant or rejuvenating. This helps to purify the blood and kill the harmful substances that are present in the bloodstream.

Dosage : 1 Capsule twice daily, with plain water, after meals.

2. GANDHAK RASAYAN

This is a classical mineral formulation that consists of shuddha gandhak (purified sulphur). This medicine is used to purify the blood and is good in pacifying the pitta dosha with rakta shodhak properties. This is used to alleviate various symptoms like fever, rashes etc, gandhak is also anti-inflammatory and used to kill the harmful microorganisms.

Dosage : 1 tablet twice or thrice daily with lukewarm water

3. SEPTRIN TABLETS

This is a patent herbal formulation consisting of various herbs like haldi (Curcuma longa), tulsi (Ocimum sanctum) and many more herbs. These all are very useful in eradicating the harmful viruses and bacterias from the body and are very helpful in purification of the blood stream. These are anti-inflammatory, anti-oxidant or rejuvenating in nature that helps this formulation to give effective results against this disease

Dosage : 1 tablet once or twice daily with plain water after meals.

4. MAHA SUDARSHAN KWATH

This is a classical herbal formulation consisting of badi harad (Terminalia chebula) Amalaki (Emblica officinalis) and many more herbs. These all herbs help to control the fever that is caused by the infections spread by Bacterias, viruses, or fungi etc. This is very helpful in lowering down the temperature of the body and is very helpful in healing the blisters, papules and Lymphadenopathy.

Dosage: 2 tsp twice daily with plain water after meals.

Contact Planet Ayurveda to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214040 Or Check Website – www.PlanetAyurveda.com

Conclusion

The crisis of monkeypox virus is getting fatal nowadays. This viral disease is just spreading day by day from the infected persons to the healthy persons. One should adopt Ayurvedic medicine to combat this disease because in Allopathy medicines they just can suggest some preventions to the disease but cannot cure this from its roots. In Ayurvedic formulations we can manage the symptoms of this disease along with can also improve the strength and immune power of the patient that can also help to control any further infections in future.

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