Author: Dr. Vikram Chauhan

Natural Treatment of Primary Biliary Cholangitis

Abstract 

Despite sky touching technologies for the treatment of disease in modern science, there are many diseases that have no medical cure. Such diseases are managed by prophylactic treatment. But even after prophylactic treatment the disease never stops growing. It grows till the stage of organ failure and a transplant is required. Sometimes conditions get so worse that even transplanted organs fail and ultimately death. One such disease is primary biliary cholangitis. This disease destroys the bile channel inside the liver. Destruction of bile channels inside of the liver results in accumulation of bile in it and thus results in cholangitis.

Introduction

In primary biliary cholangitis, biliary means related to bile duct and cholangitis means inflammation of the bile duct system. It is also termed as primary biliary cirrhosis. The main cause for this condition is damage to bile duct or bile channel due to bacterial infection or by autoimmune process. The biliary system is responsible for carrying bile to the small intestine in order to complete the digestion process. Bile also helps our body in getting rid of toxins, cholesterol and residues of red blood cells. In ayurveda this condition can be best correlated  as yakritpleehodra, a subtype of udra roga in Charaka chikitsa.

Primary Sclerosing Cholangitis

Stages of primary biliary cholangitis

The progression of this disease can be further categorized into four stages, these are:

Stage 1: (Florid) 

Bile duct damaged due to inflammatory actions.

Stage 2: (Periportal) 

Bile duct vanishes, portal or periportal inflammation with ductular proliferation.

Stage 3: (Fibrosis)

Portal fibrosis takes place.

Stage 4: (Cirrhosis)

Irreversible changes occur on and inside the liver surface.

Causes

In modern science only two causes are explained either by bacterial invasion or by the autoimmune process (tendency of body’s immune system to kill its own healthy cells).

In Ayurveda if doshas are too much accumulated inside of body and in addition a person is having poor state of digestion and use hot, saline, alkaline, burning, sour and poisoned food or intake of improper food after evacuative therapy or improper evacuative therapy, suppression of natural urges, morbidity in channels, ama dosha, obstruction due to piles etc. result in udara roga of all types.

Acharayas believed that the accumulated doshas by blocking the channels carrying sweat and fluid and affecting prana, agni and apana produce abdominal diseases (udara roga).

Symptoms of  Primary biliary cholangitis 

The symptoms initially include fatigue, itching over skin and dry eyes. But with passage of time and ignorance patient many develop severity of symptoms like pain in right upper abdomen, swelling in spleen, fat deposits around eyelids and over skin, yellowish discoloration of skin and eyes, skin darkening due to hyperpigmentation, weak brittle bones, slow buildup of fluid inside body due to liver dysfunction, ascites in case of liver failure and swollen lower limbs or ankles.

The general symptoms according to Ayurveda acharya in all udara roga includes gurgling sound in abdomen, swelling of hands and feet, poor digestion and emaciation (to grow thin), yakritpleehodar (hepatomegaly, splenomegaly), and accumulation of free fluid in abdomen. (due to bile accumulation).

Risk factors   

  • Smoking
  • Drinking alcohol in excess
  • Intake of heavy oily meals on regular basis
  • If runs in a family (genetic)
  • Obesity
  • History of any other liver condition

Diagnosis 

There are three key points out of which at least two should be fulfilling:

  1. Persistent raised levels of serum alkaline phosphatase.
  2. Presence of anti mitochondrial antibodies.
  3. Liver biopsy histology with persistent primary biliary cholangitis.

Herbal Remedies for Primary Biliary Cholangitis

In Ayurvedic aspect udara roga is the result of excessive accumulation of doshas resulting in obstruction of channels. In this case one should purge the patient daily. After he is evacuated and managed with a proper diet she should be given milk for promoting strength and after the purpose is served it should be withdrawn gradually.

Planet Ayurveda which is a leading herbal manufacturing unit offers liver care packs for the management of this condition.

Treatment of Liver Failure

Treatment of Primary biliary cholangitis

These include

  1. Yakritplihantak churna
  2. Echinacea capsules
  3. Phyllanthus niruri capsules
  4. Liver detox capsules

PRODUCT DESCRIPTION

1. Yakritplihantak churna

This blend powder is known for its effect on liver disorders. The ingredients are:

Bhumiamla (Phyllanthus niruri)

Bhumi amla is known by another name as Dukong anak. This herb has properties which can act on oedema in the liver, hyperbilirubinemia like in primary biliary cholangitis. It also detoxifies the liver. Due to its rejuvenating property nourishes the body.

Kalmegh (Andrographis paniculata)

Kalmegh which is also known as kalmegh is known for its hepatoprotective property. It balances pitta and kapha.

Katuki (Picrorhiza kurroa)

Kutaki helps in maintaining proper metabolism of liver and also in eliminating accumulated fat on liver. Regular use of kutki in particular doses helps in eliminating, cleansing and preventing gallbladder stones.

Punarnava (Boerhavia diffusa)

It is one of the famous diuretic in Ayurvedic herbs. It is having the potency to eliminate excessive water content from the body. Punarnava can be termed as a natural liver tonic and enhances kidney functioning.

Makoy (Solanum indicum)

It is called as kakamachi in sanskrit and garden nightshade in English. The extract from leaves and fruits of this plant is used in managing liver disorders.

Sharpunkha (Tephrosia purpurea

Sharpunkha is called as sarpoonkh in hindi and wild indigo in English. It helps in balancing vata and pitta dosha. Sarpunkha or sarpoonkh have excellent results in liver cirrhosis. This is also known to detoxify liver.

Kaasni (Cichorium intybus)

Kaasni is known as hinduba. This herb pacifies pitta and kapha. It is having deepana, sedative and diuretic properties. It is known to remove any kind of vascular, hepatic, visceral obstruction.

Bhringraj (Eclipta alba)

Bhringraj is known by another name in English as false daisy. The bhringraj is neetrahitkara (beneficial for eyes), jatharagni deepaka (revive digestion fire), , keshranjaka (hair vitaliser) , pachana (digestion stimulant), kapha visha nasha (eliminate kapha dosha and its toxins from body)shothahara (reduces oedema), rasayana (have rejuvenating properties), pandunut (helps in managing anaemia).

Dosage of Yakritplihantak churna: ½ teaspoon twice daily wit plain water, after meals.

2. Echinacea capsules

These capsules are made up of standardized extract of kalmegh

(Andrographis paniculata). Kalmegh is especially used in managing liver related diseases. Kalmega derived its name from its appearance. Kalmega means “dark cloud”.  It has properties to protect the liver from damage caused by free radicals. It is known to be quite effective against hepatitis B viral infection. It is antioxidant, anti-inflammatory, antipyretic, kriminashak, in various skin diseases and has hepatoprotective action.

कालमेघतु भूिनबो यवाकारफलतथा। सुितो लघुोणः

कफिपिवनाशनः।। 135।।

दीपनः वेदनो वयो वरः क्रिमिनाशक। यकृतोगेमो कुबरेचासो ॥

शयते।। 136।।

Bhuminimb is said to be Kalmega’s synonym. The fruit of having a shape like yava. Its taste is tikta (bitter), guna are laghu and ruksha, virya is ushana and action is kapha pitta nasha. It is also believed to be agni deepak (stimulates digestion), veedana nasak (analgesic), kriminashak (kills worms), used in yakrit vikara (liver disorders) and kushta roga.

Dosage: Two capsules twice daily, after meals.

3. Phyllanthus niruri capsules (Bhumiamla)

Phyllanthus niruri capsules consist of bhumiamla alone. It is having therapeutic action on the liver and kidney. It helps in eliminating accumulated toxins from both the organs. Regular use of bhumi amla in jaundice helps in reducing serum bilirubin levels naturally.

  भूधात्री  वातकृतितिक्ता कषाय मधुर हिमा 

पिपासा कासा पित्तास्त्र कफ कण्डु क्ष्तापहा (भा .प्र 298)

Qualities of bhumiamla:

  • It is pungent, sweet and astringent in taste.
  • It pacifies vata dosha, relieves thrust and cough.
  • Also pacifies pitta dosha, rakta dosha
  • Relieves swelling and itching.

Dosage: 2 capsules twice daily, after meals.

4. Liver detox capsules

These capsules are the formula prepared by Planet Ayurveda, leading herbal manufacturing unit in India and internationally. This formula consists of standardized extract of nine herbs. Nine herbs are as follows:

  • Kutki(Picrorhiza kurroa)
  • Biranjasipha (Achillea millefolium)
  • Makoy(Solanum indicum)
  • Punarnava(Boerhavia diffusa)
  • Kasni(Cichorium intybus)
  • Kalmegh (Andrographis paniculata)
  • Haritaki (Termenalia chebula)
  • Jhavuka (Tamarix galluca)
  • Himsra (Capparis spinosa)

Some of the ingredients are mentioned above and some are mentioned as following:

Biranjasipha (Achillea millefolium)

This plant is also known as yarrow. It is having properties to heal wounds. This plant is said to be used by Achilles, a greek mythology character.

Jhavuka (Tamarix galluca)

Tamarix gallica is also known as jhavuka or saltcedar. It contains an alkaloid called Tamarixin. Tamarixin is used in managing low platelet count in the body and also for treating disorders related to hepatic insufficiency.

Himsra (Capparis spinosa)

It is having antioxidant properties. This helps in liver detoxification.

Haritaki (Termenalia chebula)

This herb is well known for its analgesic properties. It also increases physical metabolism and helps to improve quality of life.

Dosage of Liver detox capsule: 2 capsules twice daily with plain water.

CONTACT MY ASSISTANT TO PROVIDE YOU THE COSTING/ORDERING AND DELIVERY INFORMATION AT – COSTING.PLANETAYURVEDA@GMAIL.COM OR CALL AT +91-172-5214030 OR CHECK WEBSITE – WWW.PLANETAYURVEDA.COM

Conclusion 

Planet Ayurveda offers products that are totally herbal and causes no side effects. These products are manufactured under the guidance of expert doctors. There is no addition of dies, fillers, additives, starch, etc. In case of any queries kindly visit our website www.planetayurveda.com

Herbal Remedies for Glanzmann’s Thrombasthenia – Bleeding Disorder

Abstract

Glanzmann’s thrombasthenia (GT) is an inherited blood clotting disorder which is characterized  by impaired function of specialized cells called as platelets that are essential for blood clotting (coagulation). The symptoms generally include abnormal bleeding and if left untreated for a long time can prove fatal. GT can be managed in a safe and effective manner with the help of Ayurvedic mode of treatment. In this article, lets’ know about this disease in brief and discuss Ayurvedic herbal remedies for the disease.

Introduction

Glanzmann’s thrombasthenia is a bleeding disorder which is characterized by spontaneous bleeding starting from birth. In Glanzmann’s Thrombasthenia a person tends to bleed easily, may also present with easy skin bruising, can have frequent nosebleeds (epistaxis) and bleeding gums. Such patients can present with purple or red spots on skin which are usually due to bleeding underneath skin or swelling caused by bleeding within tissues. People with this disorder tend to bleed a lot following injury or surgery. Females with Glanzmann’s Thrombasthenia have excessive bleeding during menses and bleed more than usual after child birth. This excessive bleeding can result in extreme blood loss and can be fatal.

Symptoms of Glanzmann's Thrombasthenia

Causes of Glanzmann’s Thrombasthenia

This condition is a result of gene mutation. The Mutation in ITGA2B or ITGB3  results in  this condition. This gene is responsible for making two parts (subunits) of receptor protein integrin alphallb/beta3. This protein is abundant on the surface of platelets. Platelets are the small cells which circulate in blood and are an important component for clot formation. During coagulation integrin helps the platelet to combine together. The clot formation protects the body after injury by sealing off the damaged blood vessels and hence bleeding stops.

The gene mutation results in the deficiency of integrin alphallb/beta3. Due to its deficiency the platelets cannot clump together thus resulting in prolonged bleeding.

In some cases of Glanzmann’s Thrombasthenia no mutation is seen in integrin alphallb/beta3. In such cases the cause for the condition is not known.

Types of Glanzmann’s Thrombasthenia

Type 1:  In this type people have less than 5 percent of integrin alphallb/beta3 levels. This is the most common type.

Type 2: In this type people have 5-20 percent of integrin alphallb/beta3 levels.

Variant type: In this type the body produces an adequate amount of integrin alphallb/beta3 but it is nonfunctional.

Symptoms of Glanzmann’s Thrombasthenia

The symptoms in this case include

  • Tendency to bleed starts right after birth or short time.
  • Purple or red spots on skin
  • Bleeding gums
  • Bleeding nose (epistaxis)
  • Excessive bleeding during surgery or after surgery.
  • Intermittent gastrointestinal bleeding resulting in melena
  • In women excessive menstrual bleeding
  • Excessive bleeding during childbirth and after childbirth
  • Intermittent uterine bleeding
  • Blood in urine
  • In severe conditions hemorrhage and this can be fatal.

Treatment of Glanzmann’s Thrombasthenia

In modern science there is no specific treatment for this condition. The treatment   includes preventive measures like protecting oneself from injuries in case to avoid blood loss, some antifibrinolytics drugs to stop excessive bleeding, blood transfusion, if required.

Planet Ayurveda is a herbal based drug manufacturer that makes products in strict adherence to the Ayurvedic texts. The various drugs that are being manufactured here are well collected from natural sources, then purified & then formulated into different preparations. These products are made under the supervision & vigilance of our expert Ayurvedic doctors by ancient time tested formulas.

Herbal Remedies for Glanzmann’s Thrombasthenia

Ayurvedic Medicines for Glanzmann’s  thrombasthenia

Planet Ayurveda offers following herbal drugs for the management of this disease

  1. Immune booster
  2. Giloy Ghan Vati
  3. Kumar Kalyan ras
  4. Green essentials
  5. Punarnava mandoor
  6. Spirulina capsules

Product Description

1. Immune booster

The immune booster capsules are made up by combining different herbs like bhumi amla (Phyllanthus niruri), amalaki (Emblica officinalis) etc. In production of these capsules standardized extract of bhumi amla, amalaki and other drugs are used. Bhumi amla is a blood purifier and also works on skin conditions. In GT it will work by purifying blood and reducing skin spots.  On the other hand, amalaki is the highest source of heat stable vitamin C which is excellent for boosting metabolism.

Dosage: Two capsules twice a day.

2. Giloy Ghan Vati

This vati uses standardized stem extract from Tinospora cordifolia plant. Medicinal effects of the plant are blood purification, antipyretic properties, anti-inflammatory effects as well as work on immune system enhancement. In GT it can help to reduce tissue swelling due to bleeding within tissues hence reducing skin spots.

Dosage: Two tablets daily.

3. Kumar Kalyan ras

The Kumar Kalyan ras is available in chewable tablet form especially for children with glanzmann’s thrombasthenia. This tablet has antipyretic properties, also used in persistent cough conditions, boosts metabolism and many more.

Dosage: one tablet twice daily (to be chewed) with honey.

4. Green essentials

This is a kind of Ayurvedic multivitamin capsules and can be used in GT as to avoid any kind of deficiency. The product contains wheatgrass which is a great source of iron, calcium, magnesium, amino acids etc. It also contains spirulina which is having a great antioxidant, anti-inflammatory and anti-allergic properties. Other ingredients are amla which is a great source of vitamin C, grape seed and green tea.

Dosage: one capsule twice daily.

5. Punarnava Mandoor

Punarnava mandoor has many ingredients like punarnava (Boerhaavia diffusa), mandoor (purified ore of iron), amalaki (Emblica officinalis), haridra (curcumin) etc. Punarnava in this formulation have anti spasmodic, anti-microbial and anti-inflammatory properties, mandoor is well known for its hematogenic and haematinic effects. This can be used in patients of GT to avoid deficiency of blood and other important minerals.

Dosage: Two tablets twice daily.

6. Spirulina Capsules

These capsules contain spirulina which is having great antioxidant, anti-inflammatory anti-allergic properties. Spirulina is also used in treating anemia. In GT this will help in maintaining normal blood levels in the body.

Dosage: 2 capsules twice daily.

Contact my assistant to provide you the costing/ordering and delivery information at – costing.planetayurveda@gmail.com or call at +91-172-5214030 Or Check Website – www.PlanetAyurveda.com

Conclusion

The products which are offered by Planet Ayurveda for the Treatment of Glanzmann’s Thrombasthenia are totally herbal which are and obtained from natural resources, so they help in treating the cause of the disease & side by side promoting immunity. These drugs also have lesser side effects as compared to the drugs/methods used by Modern medicine. However, it is advised that people suffering from Glanzmann’s Thrombasthenia should use these herbal products under the guidance of an expert Ayurveda practitioner.